An investigation of the clinical relevance of genetic polymorphism of CYP2D6 in the use of tramadol hydrochloride in post operative orthopaedic patients
Despite recent advances in anaesthesia, postoperative analgesia remains inadequate and is governed by many factors, one of which is pharmacogenetics. Fear of drug dependence exists with conventional opioid analgesics and there are needs for new drugs such as tramadol hydrochloride. Tramadol however,...
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