Simulation and modelling of a saw based resonator for mass and impedance biosensing /
This research presents the design and simulation of surface acoustic wave (SAW) resonators for biosensing applications. This novel biosensor will integrate both mass and impedance sensing techniques. Acoustic wave biosensors utilize acoustic waves propagating on the surface of piezoelectric material...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
Kuala Lumpur:
Kulliyyah of Engineering, International Islamic University Malaysia,
2013
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| Subjects: | |
| Online Access: | Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. |
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| Summary: | This research presents the design and simulation of surface acoustic wave (SAW) resonators for biosensing applications. This novel biosensor will integrate both mass and impedance sensing techniques. Acoustic wave biosensors utilize acoustic waves propagating on the surface of piezoelectric material as a detection mechanism. Any variations of the propagation path affect the velocity or amplitude of the wave. Changes in velocity can be monitored using frequency measurements which correspond to changes in mass of the propagating waves. There are many properties related to the biological cell that have to be taken into account such as its Young's modulus, Poisson's ratio and density. The device will be integrated with impedance sensing electrodes – one reference metal electrode and one working metal electrode. With the cells attached and spread on the electrodes, the impedance sensing will measure the change in impedance due to the cells placement. The novelty of the device is in the integration of mass and impedance sensing hence this is the aspect which would be the main focus. Biosensors which are currently available on-theshelves so far only provide either mass or impedance sensing – separately. Thus, the objective of this research is to simulate and find the best design that can incorporate both measurements at the same time. Study on the SAW resonators for biosensing applications will be conducted to provide concise information on this area of research. Simulations will be done using COMSOL MultiphysicsTM to find the optimum design. Several simulation models were design in simulating surface acoustic wave (SAW) and they vary with each other in terms of the delay line and interdigitated transducers' (IDTs) width. From the simulation results, it is observed that a biosensor with 6μm IDTs width has the highest eigenfrequency value which is 580MHz. Similar MEMS biosensor design was modelled to be simulated for its impedance sensing by varying the cell concentration and position of cell from the electrode plane. It could be seen that the increment in impedance value is directly proportional to the increase of cell concentration and when the cell is placed on the electrode. |
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| Physical Description: | xvi, 70 leaves : ill. ; 30cm. |
| Bibliography: | Includes bibliographical references (leaves 66-70). |