Development of an ensemble transfer learning-based convolutional neural networks model for grading of diabetic retinopathy /

Diabetic Retinopathy (DR) is one of the diseases that infect people who suffer from diabetes. This chronic disease harms the patient retina and is considered one of the main causes of total blindness for people in the mid-age. Diagnosis of this disease is time-consuming and not accessible in some co...

Full description

Saved in:
Bibliographic Details
Main Author: Sallam, Muhammad Samer (Author)
Format: Thesis
Language:English
Published: Kuala Lumpur : Kulliyyah of Engineering, International Islamic University Malaysia, 2020
Subjects:
Online Access:http://studentrepo.iium.edu.my/handle/123456789/10273
Tags: Add Tag
No Tags, Be the first to tag this record!
LEADER 042430000a22003610004500
008 200930s2020 my a f m 000 0 eng d
040 |a UIAM  |b eng  |e rda 
041 |a eng 
043 |a a-my--- 
100 1 |a Sallam, Muhammad Samer,  |e author 
245 1 |a Development of an ensemble transfer learning-based convolutional neural networks model for grading of diabetic retinopathy /  |c by Muhammad Samer Sallam 
264 1 |a Kuala Lumpur :   |b Kulliyyah of Engineering, International Islamic University Malaysia,   |c 2020 
300 |a xvi, 127 leaves :  |b illustrations ;  |c 30cm. 
336 |2 rdacontent  |a text 
337 |2 rdamedia  |a unmediated 
338 |2 rdacarrier  |a volume 
338 |2 rdacarrier  |a online resource 
347 |2 rdaft  |a text file  |b PDF 
500 |a Abstracts in English and Arabic. 
500 |a "A thesis submitted in fulfilment of the requirement for the degree of Master of Science (Computer and Information Engineering)." --On title page. 
502 |a Thesis (MSCIE)--International Islamic University Malaysia, 2020. 
504 |a Includes bibliographical references (leaves 123-127). 
520 |a Diabetic Retinopathy (DR) is one of the diseases that infect people who suffer from diabetes. This chronic disease harms the patient retina and is considered one of the main causes of total blindness for people in the mid-age. Diagnosis of this disease is time-consuming and not accessible in some countries where the number of patients is very big comparing to the number of ophthalmologists. Therefore, designing and developing automated systems to grade DR is considered one of the recent research areas in the world of medical image applications. In this research, a complete pipeline for retinal fundus images processing and analysis was described, implemented and evaluated. This pipeline has three main stages: (i) image pre-processing, (ii) features extraction and (iii) classification. In the first stage, the image was pre-processed using different transformations techniques. In the second stage, the convolution neural network algorithm (CNN) was used. The concept of transfer learning and fine-tuning were advocated in this research. ResNet, DenseNet, and SqueezeNet were fine-tuned in order to implement the features extraction stage. For the classifier in the last stage, decision tree-based algorithms with the concept of ensemble learning were used where Random Forest, XGBoost and LightGBM were implemented and evaluated. Kaggle diabetic retinopathy dataset, a publicly available dataset, of retinal fundus image was used for training and testing. The problem of DR diagnosis was handled as a multi-class classification problem where there are five levels of the disease severity (0 – No DR, 1 – Mild, 2 – Moderate, 3 – Severe, 4 – Proliferative DR). The final model developed in this research used ResNet101 and DenseNet169 for features extraction, and it used the XGBoost for classification. It produced a very accurate performance with a quadratic weighted kappa score of 91.4% and an accuracy of 96.5%. This research proves that using CNN as a features-extractor algorithm is highly efficient since it produced representative features for the used images dataset. It shows that using the imbalanced dataset sampler is a very efficient solution to handle the issue of the imbalanced dataset. Also, it proves that ensemble learning algorithms are very promising algorithms to be used since they produced a very accurate model. The final model developed in this research could be used as the main unit for a computer-aided system (CAD) to be hosted online for DR diagnosis. 
596 |a 1 
655 7 |a Theses, IIUM local 
690 |a Dissertations, Academic  |x Department of Electrical and Computer Engineering  |z IIUM 
700 1 |a Rashidah Funke Olanrewaju,  |e degree supervisor 
700 0 |a Ani Liza Asnawi,  |e degree supervisor 
710 2 |a International Islamic University Malaysia.  |b Department of Electrical and Computer Engineering 
856 4 |u http://studentrepo.iium.edu.my/handle/123456789/10273 
900 |a sz to nzj 
999 |c 439212  |d 470951 
952 |0 0  |6 XX(563861.1)  |7 0  |8 THESES  |9 762276  |a IIUM  |b IIUM  |c MULTIMEDIA  |g 0.00  |o XX(563861.1)  |p 11100418352  |r 1900-01-02  |t 1  |v 0.00  |y THESIS