Prognostic factors affecting the functional recovery in spinal tuberculosis patients with neurological deficit /

This study is aimed to determine the factors associated with the functional recovery in spinal tuberculosis patients with neurology deficits. To assess clinical, biochemical and radiological parametersin relation to the prognostic factors. This cross-sectional study from July 2017 to June 2018, pati...

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Bibliographic Details
Main Author: Harkeerat Singh Sukhdarshan Singh (Author)
Format: Thesis
Language:English
Published: Kuantan, Pahang : Kulliyyah of Medicine, International Islamic University Malaysia, 2019
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Online Access:Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library.
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040 |a UIAM  |b eng  |e rda 
041 |a eng 
043 |a a-my--- 
100 1 |a Harkeerat Singh Sukhdarshan Singh,  |e author 
245 1 |a Prognostic factors affecting the functional recovery in spinal tuberculosis patients with neurological deficit /  |c by Harkeerat Singh Sukhdarshan Singh 
264 1 |a Kuantan, Pahang :  |b Kulliyyah of Medicine, International Islamic University Malaysia,  |c 2019 
300 |a xi, 58 leaves :  |b illustrations ;  |c 30cm. 
336 |2 rdacontent  |a text 
337 |2 rdamedia  |a unmediated 
338 |2 rdacarrier  |a volume 
338 |2 rdacarrier  |a online resource 
347 |2 rdaft  |a text file  |b PDF 
500 |a Abstracts in English. 
500 |a "A dissertation submitted in fulfilment of the requirement for the degree of Master of Orthopaedic Surgery." --On title page. 
502 |a Thesis (MORTH)--International Islamic University Malaysia, 2019. 
504 |a Includes bibliographical references (leaves 40-43). 
520 |a This study is aimed to determine the factors associated with the functional recovery in spinal tuberculosis patients with neurology deficits. To assess clinical, biochemical and radiological parametersin relation to the prognostic factors. This cross-sectional study from July 2017 to June 2018, patients presenting to 3 hospitals in Sabah, with significant neurology fulfilling the inclusion criteria were enrolled. Diagnosis of spinal tuberculosis was determined either by clinical radiological factors and confirmed with histopathology, microbacteriology and immunoassay. Patients with significant neurology received standard treatment protocol according to the middle pathway regime, receiving anti tuberculosis for the first 3 weeks and were subjected to surgery if there were no improvement. Modified Barthel Index (MBI) was used to asses functional outcome, scores were taken before and after treatment and with improvement of 4 points or a total of more than 12 were considered as good outcome. After a year, 146 patients (65.1%) had good functional recovery and 78 patients had no significant improvement. On univariate analysis, there was no significant correlation with age (p>0.45), duration of symptoms (p>0.68), CRP (p>0.76), WCC (p>0.99), and presence of soft tissue collection (p>0.21) with functional outcome. High ESR (p<0.008) and thoracolumbar lesions are associated with a poor functional recovery (p<0.033). In conclusion, higher ESR values, numbers of vertebrae involved, and thoracolumbar lesions are associated with poor functional outcome in spinal tuberculosis patients. 
596 |a 6 
655 7 |a Theses, IIUM local 
690 |a Dissertations, Academic  |x Department of Orthopaedics,Traumatology & Rehabilitation  |z IIUM 
700 0 |a Zamzuri Zakaria,  |e degree supervisor 
710 2 |a International Islamic University Malaysia.  |b Department of Orthopaedics,Traumatology & Rehabilitation 
856 4 |u http://studentrepo.iium.edu.my/handle/123456789/10343  |z Click here to view 1st 24 pages of the thesis. Members can view fulltext at the specified PCs in the library. 
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