Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin

A schiff base ligand, S-2-fluorobenzyl 2-(5-chloro-2-oxoindolin-3- ylidene)hydrazinecarbodithioate was synthesized via the condensation reaction between S-2- fluorobenzyldithiocarbazate and 5-chloroisatin. The Schiff base was reacted with Cu(II) and Ni(II) metal salts to produce metal complexes. The...

Full description

Saved in:

Bibliographic Details
Main Author:	Arifin, Nurul Amalina
Format:	Thesis
Language:	English
Published:	2010
Online Access:	https://ir.uitm.edu.my/id/eprint/104113/1/104113.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-uitm-ir.104113
record_format	uketd_dc
spelling	my-uitm-ir.1041132024-09-30T08:26:59Z Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin 2010 Arifin, Nurul Amalina A schiff base ligand, S-2-fluorobenzyl 2-(5-chloro-2-oxoindolin-3- ylidene)hydrazinecarbodithioate was synthesized via the condensation reaction between S-2- fluorobenzyldithiocarbazate and 5-chloroisatin. The Schiff base was reacted with Cu(II) and Ni(II) metal salts to produce metal complexes. The Schiff base and its metal complexes were characterized by elemental analysis and various physico-chemical techniques. The ligand was capable of being a versatile chelating ligand. It acted as a uninegatively charged bidentate ligand when it was bonded to Cu(II) ion via the azomethine nitrogen and thiolate sulfur. In the Ni(II) complex, it acted as a uninegatively charged tridentate ligand when it was bonded to the metal ion through carbonylic oxygen. Square planar geometry was assigned to the Cu(II) complex and Ni(II) complex exhibit the tetrahedral geometry. Antibacterial screening was done on the Schiff base ligand and its metal complexes. Cu(II) complex showed that it was moderately active against the Gram positive bacteria strain and Cu(II) complex also showed lower activity against the Gram negative bacteria strain. Both Schiff base ligand and Ni(II) complex showed no activity against the Gram negative bacterial strain. 2010 Thesis https://ir.uitm.edu.my/id/eprint/104113/ https://ir.uitm.edu.my/id/eprint/104113/1/104113.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Applied Science Rashid, Shadatul Hanum
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Rashid, Shadatul Hanum
description	A schiff base ligand, S-2-fluorobenzyl 2-(5-chloro-2-oxoindolin-3- ylidene)hydrazinecarbodithioate was synthesized via the condensation reaction between S-2- fluorobenzyldithiocarbazate and 5-chloroisatin. The Schiff base was reacted with Cu(II) and Ni(II) metal salts to produce metal complexes. The Schiff base and its metal complexes were characterized by elemental analysis and various physico-chemical techniques. The ligand was capable of being a versatile chelating ligand. It acted as a uninegatively charged bidentate ligand when it was bonded to Cu(II) ion via the azomethine nitrogen and thiolate sulfur. In the Ni(II) complex, it acted as a uninegatively charged tridentate ligand when it was bonded to the metal ion through carbonylic oxygen. Square planar geometry was assigned to the Cu(II) complex and Ni(II) complex exhibit the tetrahedral geometry. Antibacterial screening was done on the Schiff base ligand and its metal complexes. Cu(II) complex showed that it was moderately active against the Gram positive bacteria strain and Cu(II) complex also showed lower activity against the Gram negative bacteria strain. Both Schiff base ligand and Ni(II) complex showed no activity against the Gram negative bacterial strain.
format	Thesis
qualification_level	Bachelor degree
author	Arifin, Nurul Amalina
spellingShingle	Arifin, Nurul Amalina Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
author_facet	Arifin, Nurul Amalina
author_sort	Arifin, Nurul Amalina
title	Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
title_short	Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
title_full	Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
title_fullStr	Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
title_full_unstemmed	Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin
title_sort	synthesis, characterization, and antibacterial activity of cu (ii) and ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / nurul amalina arifin
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Applied Science
publishDate	2010
url	https://ir.uitm.edu.my/id/eprint/104113/1/104113.pdf
_version_	1811769278241701888

Synthesis, characterization, and antibacterial activity of Cu (ii) and Ni (ii) transition metal complexes of nos tridentate schiff base derived from s-2-fluorobenzyldithiocarbazate with 5-chloroisatin / Nurul Amalina Arifin

Similar Items