Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid

The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improvi...

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Main Author: Che Hamid, Norazura
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/105206/1/105206.PDF
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spelling my-uitm-ir.1052062024-12-05T09:06:59Z Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid 2009 Che Hamid, Norazura Pharmacopoeias Pharmaceutical dosage forms Pharmaceutical supplies The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improving solubility of the drug, but no detailed explanation about the molecular processes during the improving phenomenon. The present study deals with experiments so to highlight solute solvent interaction and related modifications in case of the presence of hydrotropic agents. Contact angle was carried out in order to obtain valuable information regarding the solute solvent interactions. 2009 Thesis https://ir.uitm.edu.my/id/eprint/105206/ https://ir.uitm.edu.my/id/eprint/105206/1/105206.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Tripathy, Minaketan
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Tripathy, Minaketan
topic Pharmacopoeias
Pharmaceutical dosage forms
Pharmaceutical supplies
spellingShingle Pharmacopoeias
Pharmaceutical dosage forms
Pharmaceutical supplies
Che Hamid, Norazura
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
description The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improving solubility of the drug, but no detailed explanation about the molecular processes during the improving phenomenon. The present study deals with experiments so to highlight solute solvent interaction and related modifications in case of the presence of hydrotropic agents. Contact angle was carried out in order to obtain valuable information regarding the solute solvent interactions.
format Thesis
qualification_level Bachelor degree
author Che Hamid, Norazura
author_facet Che Hamid, Norazura
author_sort Che Hamid, Norazura
title Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
title_short Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
title_full Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
title_fullStr Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
title_full_unstemmed Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
title_sort investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / norazura che hamid
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/105206/1/105206.PDF
_version_ 1818588139273322496