Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid
The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improvi...
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2009
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my-uitm-ir.1052062024-12-05T09:06:59Z Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid 2009 Che Hamid, Norazura Pharmacopoeias Pharmaceutical dosage forms Pharmaceutical supplies The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improving solubility of the drug, but no detailed explanation about the molecular processes during the improving phenomenon. The present study deals with experiments so to highlight solute solvent interaction and related modifications in case of the presence of hydrotropic agents. Contact angle was carried out in order to obtain valuable information regarding the solute solvent interactions. 2009 Thesis https://ir.uitm.edu.my/id/eprint/105206/ https://ir.uitm.edu.my/id/eprint/105206/1/105206.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Tripathy, Minaketan |
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Universiti Teknologi MARA |
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UiTM Institutional Repository |
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English |
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Tripathy, Minaketan |
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Pharmacopoeias Pharmaceutical dosage forms Pharmaceutical supplies |
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Pharmacopoeias Pharmaceutical dosage forms Pharmaceutical supplies Che Hamid, Norazura Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
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The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improving solubility of the drug, but no detailed explanation about the molecular processes during the improving phenomenon. The present study deals with experiments so to highlight solute solvent interaction and related modifications in case of the presence of hydrotropic agents. Contact angle was carried out in order to obtain valuable information regarding the solute solvent interactions. |
format |
Thesis |
qualification_level |
Bachelor degree |
author |
Che Hamid, Norazura |
author_facet |
Che Hamid, Norazura |
author_sort |
Che Hamid, Norazura |
title |
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
title_short |
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
title_full |
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
title_fullStr |
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
title_full_unstemmed |
Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid |
title_sort |
investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / norazura che hamid |
granting_institution |
Universiti Teknologi MARA (Kampus Puncak Alam) |
granting_department |
Faculty of Pharmacy |
publishDate |
2009 |
url |
https://ir.uitm.edu.my/id/eprint/105206/1/105206.PDF |
_version_ |
1818588139273322496 |