Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki

Bisphenol A (BPA) or 2,2-bis-(4-hydroxyphenil)propane is a monomer used in the production of its polymers which are polycarbonate plastics and epoxy resins. It is an organic compound which is extensively used as daily consumer products also has been found widespread in the environment. It is also kn...

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Main Author:	Mohd Marzuki, Norfazihan
Format:	Thesis
Language:	English
Published:	2009
Subjects:	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic) Pharmaceutical chemistry
Online Access:	https://ir.uitm.edu.my/id/eprint/105212/1/105212.PDF
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id	my-uitm-ir.105212
record_format	uketd_dc
spelling	my-uitm-ir.1052122024-12-05T09:06:44Z Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki 2009 Mohd Marzuki, Norfazihan Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Pharmaceutical chemistry Bisphenol A (BPA) or 2,2-bis-(4-hydroxyphenil)propane is a monomer used in the production of its polymers which are polycarbonate plastics and epoxy resins. It is an organic compound which is extensively used as daily consumer products also has been found widespread in the environment. It is also known as one of the most ubiquotous environmental endocrine disruptor compound. Without realizing about the danger that it brings along, BP A is frequently ingested or absorbed by humans and pass through into the body. The study focused on the duration of BPA towards the induction of oxidative stress in the rat's brain. Oxidative stress is when the oxidants in the body are more intense compared to the antioxidants, then lead to cell damage. Antioxidants for example glutathione peroxidase (GPx) are the compound that responsible for defense against oxidants. BP A can induce oxidative stress in the brain by altering the properties of oxidants and also antioxidants. BP A administration did alter the body weight of female SD rats and impaired the development of the brain in longer duration of exposure. BP A also decreased the GPx activity and overall antioxidant concentration in the brain of female SD rats. 2009 Thesis https://ir.uitm.edu.my/id/eprint/105212/ https://ir.uitm.edu.my/id/eprint/105212/1/105212.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Mohd Jofrry, Suhaidah
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Mohd Jofrry, Suhaidah
topic	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic) Pharmaceutical chemistry
spellingShingle	Pharmacognosy Pharmaceutical substances (Plant, animal, and inorganic) Pharmaceutical chemistry Mohd Marzuki, Norfazihan Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
description	Bisphenol A (BPA) or 2,2-bis-(4-hydroxyphenil)propane is a monomer used in the production of its polymers which are polycarbonate plastics and epoxy resins. It is an organic compound which is extensively used as daily consumer products also has been found widespread in the environment. It is also known as one of the most ubiquotous environmental endocrine disruptor compound. Without realizing about the danger that it brings along, BP A is frequently ingested or absorbed by humans and pass through into the body. The study focused on the duration of BPA towards the induction of oxidative stress in the rat's brain. Oxidative stress is when the oxidants in the body are more intense compared to the antioxidants, then lead to cell damage. Antioxidants for example glutathione peroxidase (GPx) are the compound that responsible for defense against oxidants. BP A can induce oxidative stress in the brain by altering the properties of oxidants and also antioxidants. BP A administration did alter the body weight of female SD rats and impaired the development of the brain in longer duration of exposure. BP A also decreased the GPx activity and overall antioxidant concentration in the brain of female SD rats.
format	Thesis
qualification_level	Bachelor degree
author	Mohd Marzuki, Norfazihan
author_facet	Mohd Marzuki, Norfazihan
author_sort	Mohd Marzuki, Norfazihan
title	Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
title_short	Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
title_full	Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
title_fullStr	Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
title_full_unstemmed	Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki
title_sort	time response study of bisphenol a (bpa) towards the induction of oxidative stress in the brain of sprague dawley female rats / norfazihan mohd marzuki
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2009
url	https://ir.uitm.edu.my/id/eprint/105212/1/105212.PDF
_version_	1818588140013617152

Time response study of bisphenol A (BPA) towards the induction of oxidative stress in the brain of sprague dawley female rats / Norfazihan Mohd Marzuki

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