The effects of diabetes on female sex hormone levels / Nur Shahirul Saidin
We analyzed the effects of streptozotocin-induced diabetes on the female hormone level in Wister Kyoto (WKY) rats. There was reduced sensitive of estradiol and progesterone in diabetes mellitus compared to levels in normal tissue and serum. Both hormones were slightly lower in female diabetic rats c...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ir.uitm.edu.my/id/eprint/105854/1/105854.PDF |
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| Summary: | We analyzed the effects of streptozotocin-induced diabetes on the female hormone level in Wister Kyoto (WKY) rats. There was reduced sensitive of estradiol and progesterone in diabetes mellitus compared to levels in normal tissue and serum. Both hormones were slightly lower in female diabetic rats compared to non diabetic rats. Diabetes may disrupt steroidogenesis or alter the Hypothalamus-Pituitary-Gonadal (HPG) axis function. Estradiol was lower compared to progesterone in diabetic aorta probably due to diabetes induced loss of estrogenic signaling m female WKY rats. |
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