Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin

Bisphenol A (BP A) is one of the most widely used chemical component nowadays. Human beings are highly exposed to BPA, thus any significant adverse effects due to exposure to the BP A become a main concern among the researchers. Purposes of this study are to study effects of BPA towards body weight,...

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Main Author: Zainal Abidin, Khairul Naim
Format: Thesis
Language:English
Published: 2009
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Online Access:https://ir.uitm.edu.my/id/eprint/106680/1/106680.PDF
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spelling my-uitm-ir.1066802024-12-10T23:13:21Z Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin 2009 Zainal Abidin, Khairul Naim Pharmaceutical industry Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) Bisphenol A (BP A) is one of the most widely used chemical component nowadays. Human beings are highly exposed to BPA, thus any significant adverse effects due to exposure to the BP A become a main concern among the researchers. Purposes of this study are to study effects of BPA towards body weight, weight of male reproductive organs and plasma protein concentration in relation to time response. Male rats were administered daily dose of BPA (100 mcg/kg/day), ethinyl estradiol and Tween-80 for duration ranging from 7 days, 14 days and 28 days. BPA exposure up to 28 days caused significant increase in body weight of rats, however there are lack of evidence on effects of BP A towards weight of prostate gland and testes. BP A caused significant increase in plasma protein concentration when rats were exposed to BP A up to 14 days, further exposure more than 14 days did not cause any increment in plasma protein concentration. The present study showed BPA will increase rate of weight gain of rats when exposed for a long period of time and increase in plasma protein concentration when exposed up to 14 days. 2009 Thesis https://ir.uitm.edu.my/id/eprint/106680/ https://ir.uitm.edu.my/id/eprint/106680/1/106680.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Jalaludin, Nadia
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Jalaludin, Nadia
topic Pharmaceutical industry
Pharmaceutical industry
spellingShingle Pharmaceutical industry
Pharmaceutical industry
Zainal Abidin, Khairul Naim
Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
description Bisphenol A (BP A) is one of the most widely used chemical component nowadays. Human beings are highly exposed to BPA, thus any significant adverse effects due to exposure to the BP A become a main concern among the researchers. Purposes of this study are to study effects of BPA towards body weight, weight of male reproductive organs and plasma protein concentration in relation to time response. Male rats were administered daily dose of BPA (100 mcg/kg/day), ethinyl estradiol and Tween-80 for duration ranging from 7 days, 14 days and 28 days. BPA exposure up to 28 days caused significant increase in body weight of rats, however there are lack of evidence on effects of BP A towards weight of prostate gland and testes. BP A caused significant increase in plasma protein concentration when rats were exposed to BP A up to 14 days, further exposure more than 14 days did not cause any increment in plasma protein concentration. The present study showed BPA will increase rate of weight gain of rats when exposed for a long period of time and increase in plasma protein concentration when exposed up to 14 days.
format Thesis
qualification_level Bachelor degree
author Zainal Abidin, Khairul Naim
author_facet Zainal Abidin, Khairul Naim
author_sort Zainal Abidin, Khairul Naim
title Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
title_short Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
title_full Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
title_fullStr Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
title_full_unstemmed Study on protein concentration changes and body weight changes in male bisphenol A - treated sprague dawley rats in relation to time response / Khairul Naim Zainal Abidin
title_sort study on protein concentration changes and body weight changes in male bisphenol a - treated sprague dawley rats in relation to time response / khairul naim zainal abidin
granting_institution Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department Faculty of Pharmacy
publishDate 2009
url https://ir.uitm.edu.my/id/eprint/106680/1/106680.PDF
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