Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha

Medicinal plants have gained the interest of many researchers from all over the world. In the countries, herbal medicine has remained as the main therapy due to the availability and perhaps culture preferences. The researchers from various disciplines challenged their great concerned to discover the...

Full description

Saved in:

Bibliographic Details
Main Author:	Wan Mohd Mustapha, Wan Norsuhada
Format:	Thesis
Language:	English
Published:	2009
Subjects:	Pharmaceutical industry Pharmaceutical chemistry
Online Access:	https://ir.uitm.edu.my/id/eprint/107031/1/107031.PDF
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-uitm-ir.107031
record_format	uketd_dc
spelling	my-uitm-ir.1070312024-12-10T23:13:15Z Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha 2009 Wan Mohd Mustapha, Wan Norsuhada Pharmaceutical industry Pharmaceutical chemistry Medicinal plants have gained the interest of many researchers from all over the world. In the countries, herbal medicine has remained as the main therapy due to the availability and perhaps culture preferences. The researchers from various disciplines challenged their great concerned to discover the benefit of the medical plants by using modern medicinal equipment. In this study, the investigation of Vitex trifolia was limited to characterizing the constituents from the chloroform extract of the leaves. Further studies were considered to be interesting as the benefits of Vitex species were traditionally approved used to treat wide range of ailment. The extracts were introduced to thin layer chromatography (TLC) to clarify the bands. The band which contained interesting compounds was subjected to silica column chromatography. Fractions collected were again introduced to TLC. The chemical composition of the crude drug extract were analyzed and observed under ultraviolet light. Compounds of interest were subjected to Nuclear Magnetic Resonance (NMR). From NMR, two compounds, compound 2 and compound 4 can be suggested. Compound 2 was suggested to have polymethoxyl and methyl substituents similar to which present in ecdysteroid group. Meanwhile compound 4 was suggested as quercetin pentamethyl ether. 2009 Thesis https://ir.uitm.edu.my/id/eprint/107031/ https://ir.uitm.edu.my/id/eprint/107031/1/107031.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Abdul Wahab, lbtisam
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Abdul Wahab, lbtisam
topic	Pharmaceutical industry Pharmaceutical chemistry
spellingShingle	Pharmaceutical industry Pharmaceutical chemistry Wan Mohd Mustapha, Wan Norsuhada Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
description	Medicinal plants have gained the interest of many researchers from all over the world. In the countries, herbal medicine has remained as the main therapy due to the availability and perhaps culture preferences. The researchers from various disciplines challenged their great concerned to discover the benefit of the medical plants by using modern medicinal equipment. In this study, the investigation of Vitex trifolia was limited to characterizing the constituents from the chloroform extract of the leaves. Further studies were considered to be interesting as the benefits of Vitex species were traditionally approved used to treat wide range of ailment. The extracts were introduced to thin layer chromatography (TLC) to clarify the bands. The band which contained interesting compounds was subjected to silica column chromatography. Fractions collected were again introduced to TLC. The chemical composition of the crude drug extract were analyzed and observed under ultraviolet light. Compounds of interest were subjected to Nuclear Magnetic Resonance (NMR). From NMR, two compounds, compound 2 and compound 4 can be suggested. Compound 2 was suggested to have polymethoxyl and methyl substituents similar to which present in ecdysteroid group. Meanwhile compound 4 was suggested as quercetin pentamethyl ether.
format	Thesis
qualification_level	Bachelor degree
author	Wan Mohd Mustapha, Wan Norsuhada
author_facet	Wan Mohd Mustapha, Wan Norsuhada
author_sort	Wan Mohd Mustapha, Wan Norsuhada
title	Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
title_short	Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
title_full	Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
title_fullStr	Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
title_full_unstemmed	Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha
title_sort	chromatographic study of vitex chloroform extract / wan norsuhada wan mohd mustapha
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2009
url	https://ir.uitm.edu.my/id/eprint/107031/1/107031.PDF
_version_	1818588201840803840

Chromatographic study of vitex chloroform extract / Wan Norsuhada Wan Mohd Mustapha

Similar Items