Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif

The aim of this study was to determine the possible influence of sex hormones on the contractile responses induced by phenylephrine and angiotensin II, in endothelium intact and denuded tissues. For this purpose, thoracic aorta segments from female WKY rats were used. Endothelium denuded aorta exhib...

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Main Author:	Abdul Latif, Nurul Hananni
Format:	Thesis
Language:	English
Published:	2009
Subjects:	Pharmaceutical industry Pharmaceutical chemistry
Online Access:	https://ir.uitm.edu.my/id/eprint/107049/1/107049.PDF
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id	my-uitm-ir.107049
record_format	uketd_dc
spelling	my-uitm-ir.1070492024-12-08T16:49:17Z Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif 2009 Abdul Latif, Nurul Hananni Pharmaceutical industry Pharmaceutical chemistry The aim of this study was to determine the possible influence of sex hormones on the contractile responses induced by phenylephrine and angiotensin II, in endothelium intact and denuded tissues. For this purpose, thoracic aorta segments from female WKY rats were used. Endothelium denuded aorta exhibited higher sensitivity to phenylephrine and angiotensin II contractility compared to endothelium intact tissues as tissue denudation remove endothelium which inhibit contractile agonist. States of estrous cycle modulated phenylephrine induced contractile responses more in endothelium intact tissues compared to angiotensin II and equally regulated responses for phenyelephrine and angiotensin II in endothelium denuded tissues. 2009 Thesis https://ir.uitm.edu.my/id/eprint/107049/ https://ir.uitm.edu.my/id/eprint/107049/1/107049.PDF text en public degree Universiti Teknologi MARA (Kampus Puncak Alam) Faculty of Pharmacy Iguegbe, Aloysius Umelo
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Iguegbe, Aloysius Umelo
topic	Pharmaceutical industry Pharmaceutical chemistry
spellingShingle	Pharmaceutical industry Pharmaceutical chemistry Abdul Latif, Nurul Hananni Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
description	The aim of this study was to determine the possible influence of sex hormones on the contractile responses induced by phenylephrine and angiotensin II, in endothelium intact and denuded tissues. For this purpose, thoracic aorta segments from female WKY rats were used. Endothelium denuded aorta exhibited higher sensitivity to phenylephrine and angiotensin II contractility compared to endothelium intact tissues as tissue denudation remove endothelium which inhibit contractile agonist. States of estrous cycle modulated phenylephrine induced contractile responses more in endothelium intact tissues compared to angiotensin II and equally regulated responses for phenyelephrine and angiotensin II in endothelium denuded tissues.
format	Thesis
qualification_level	Bachelor degree
author	Abdul Latif, Nurul Hananni
author_facet	Abdul Latif, Nurul Hananni
author_sort	Abdul Latif, Nurul Hananni
title	Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
title_short	Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
title_full	Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
title_fullStr	Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
title_full_unstemmed	Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif
title_sort	effects of estrous cycle on vascular contractility in the presence and absence of endothelium / nurul hananni abdul latif
granting_institution	Universiti Teknologi MARA (Kampus Puncak Alam)
granting_department	Faculty of Pharmacy
publishDate	2009
url	https://ir.uitm.edu.my/id/eprint/107049/1/107049.PDF
_version_	1818588203823661056

Effects of estrous cycle on vascular contractility in the presence and absence of endothelium / Nurul Hananni Abdul Latif

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