Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail

Aqueous extract Prismatomeris glabra root has been used long time ago in Malaysia because of its advantages. People in Malaysia believe that this plant has ergogenic effect, to maintain wellness and to enhance physical stamina. It has also been used as an aphrodisiac in some population people in Mal...

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Main Author: Ismail, Norhamizah
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/66744/1/66744.pdf
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spelling my-uitm-ir.667442022-09-15T00:28:23Z Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail 2012 Ismail, Norhamizah Botanical chemistry. Phytochemicals Medical botany (General) Aqueous extract Prismatomeris glabra root has been used long time ago in Malaysia because of its advantages. People in Malaysia believe that this plant has ergogenic effect, to maintain wellness and to enhance physical stamina. It has also been used as an aphrodisiac in some population people in Malaysia. Besides that, not much study has been carried out previously in Malaysia for this plant. This plant was selected for this study because of its advantage and its used as traditional folk remedy. Thus, this study is conducted to investigate the chemical constituents from this plan. In order to achieve the objectives, several steps were carried out. First, an appropriate solvent system was selected and used for High Performance Liquid Chromatography technique (HPLC). HPLC was performed on reverse phase chromatography. Detection of compound using HPLC was carried out at 240 nm to visualize the chemical compounds. The compounds of interest were then isolated and purified using an appropriate solvent system consisting of methanol, Acetonitrile and Distilled water. The pure compound(s) obtained undergo several analytical methods to identify the structure. The method used was spectroscopic technique using Nuclear Magnetic Resonance (NMR) through 1H-NMR analysis. 1H-NMR spectrum was run on Bruker Spectrometers at 500 MHz. The structural elucidations were based on the analysis of physical and spectroscopic data but due to insufficient amount of sample obtained, the NMR results were not good. Thus, further studies should be done to elucidate the compounds of this plant. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66744/ https://ir.uitm.edu.my/id/eprint/66744/1/66744.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Al-Kadi, Khaled Abdullah
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Al-Kadi, Khaled Abdullah
topic Botanical chemistry
Phytochemicals
Medical botany (General)
spellingShingle Botanical chemistry
Phytochemicals
Medical botany (General)
Ismail, Norhamizah
Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
description Aqueous extract Prismatomeris glabra root has been used long time ago in Malaysia because of its advantages. People in Malaysia believe that this plant has ergogenic effect, to maintain wellness and to enhance physical stamina. It has also been used as an aphrodisiac in some population people in Malaysia. Besides that, not much study has been carried out previously in Malaysia for this plant. This plant was selected for this study because of its advantage and its used as traditional folk remedy. Thus, this study is conducted to investigate the chemical constituents from this plan. In order to achieve the objectives, several steps were carried out. First, an appropriate solvent system was selected and used for High Performance Liquid Chromatography technique (HPLC). HPLC was performed on reverse phase chromatography. Detection of compound using HPLC was carried out at 240 nm to visualize the chemical compounds. The compounds of interest were then isolated and purified using an appropriate solvent system consisting of methanol, Acetonitrile and Distilled water. The pure compound(s) obtained undergo several analytical methods to identify the structure. The method used was spectroscopic technique using Nuclear Magnetic Resonance (NMR) through 1H-NMR analysis. 1H-NMR spectrum was run on Bruker Spectrometers at 500 MHz. The structural elucidations were based on the analysis of physical and spectroscopic data but due to insufficient amount of sample obtained, the NMR results were not good. Thus, further studies should be done to elucidate the compounds of this plant.
format Thesis
qualification_level Bachelor degree
author Ismail, Norhamizah
author_facet Ismail, Norhamizah
author_sort Ismail, Norhamizah
title Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
title_short Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
title_full Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
title_fullStr Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
title_full_unstemmed Identification of phytochemical constituents from roots of Prismatomeris glabra / Norhamizah Ismail
title_sort identification of phytochemical constituents from roots of prismatomeris glabra / norhamizah ismail
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Pharmacy
publishDate 2012
url https://ir.uitm.edu.my/id/eprint/66744/1/66744.pdf
_version_ 1783735636791918592