Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan

Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activat...

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Main Author: Mohd Adnan, Nurul Farah Hana
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/66801/1/66801.pdf
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spelling my-uitm-ir.668012022-09-15T06:29:18Z Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan 2012 Mohd Adnan, Nurul Farah Hana Cytology Research. Experimentation Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activation of caspase-3 and -9 were observed in all-Gelam honey-treated cancer cells indicating the involvement of mitochondrial apoptotic pathway. This study shows that Gelam honey has significant anticancer activity against colorectal cancer cell lines. 2012 Thesis https://ir.uitm.edu.my/id/eprint/66801/ https://ir.uitm.edu.my/id/eprint/66801/1/66801.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Pharmacy Wan Ismail, Wan Iryani
institution Universiti Teknologi MARA
collection UiTM Institutional Repository
language English
advisor Wan Ismail, Wan Iryani
topic Cytology
Cytology
spellingShingle Cytology
Cytology
Mohd Adnan, Nurul Farah Hana
Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
description Honey is reported to contain various compounds such as phenols, vitamins and antioxidants. The present study investigates the anticancer potential of Gelam honey in colorectal cancer cell lines (HCT116). The cells were treated with decreasing doses of Gelam honey (10-0.01%) for 72 hours. The activation of caspase-3 and -9 were observed in all-Gelam honey-treated cancer cells indicating the involvement of mitochondrial apoptotic pathway. This study shows that Gelam honey has significant anticancer activity against colorectal cancer cell lines.
format Thesis
qualification_level Bachelor degree
author Mohd Adnan, Nurul Farah Hana
author_facet Mohd Adnan, Nurul Farah Hana
author_sort Mohd Adnan, Nurul Farah Hana
title Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
title_short Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
title_full Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
title_fullStr Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
title_full_unstemmed Effects of gelam (Melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (HCT116) / Nurul Farah Hana Mohd Adnan
title_sort effects of gelam (melaleuca sp.) honey on apoptosis pathway of colorectal cancer cell lines (hct116) / nurul farah hana mohd adnan
granting_institution Universiti Teknologi MARA (UiTM)
granting_department Faculty of Pharmacy
publishDate 2012
url https://ir.uitm.edu.my/id/eprint/66801/1/66801.pdf
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