Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali

Glaucoma is the major cause of an irreversible blindness worldwide and it is commonly associated with an elevation of intraocular pressure. ACE inhibitors have been shown to have ocular hypotensive effect in animals and human subjects. The aim of the study was to evaluate the ocular hypotensive effe...

Full description

Saved in:

Bibliographic Details
Main Author:	Zaukafali, Tajul Atiqah
Format:	Thesis
Language:	English
Published:	2013
Subjects:	QP Physiology Particular diseases of the eye
Online Access:	https://ir.uitm.edu.my/id/eprint/72215/1/72215.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-uitm-ir.72215
record_format	uketd_dc
spelling	my-uitm-ir.722152024-01-05T03:49:19Z Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali 2013 Zaukafali, Tajul Atiqah QP Physiology Particular diseases of the eye Glaucoma is the major cause of an irreversible blindness worldwide and it is commonly associated with an elevation of intraocular pressure. ACE inhibitors have been shown to have ocular hypotensive effect in animals and human subjects. The aim of the study was to evaluate the ocular hypotensive effect and the effect on attenuation of trabecular meshwork remodelling by topical application of ACE inhibitor, enalaprilat dehydrate in chronic steroid-induced ocular hypertensive rat model. Ocular hypertension was developed in normotensive Sprague Dawley rats (100-120g) of either sex by topical instillation of dexamethasone 0.1%, 2 times daily for 36 days. The rats that developed more than 25% rise in IOP were considered ocular hypertensive. 2013 Thesis https://ir.uitm.edu.my/id/eprint/72215/ https://ir.uitm.edu.my/id/eprint/72215/1/72215.pdf text en public degree Universiti Teknologi MARA (UiTM) Faculty of Medicine Krasilnikova, Anna
institution	Universiti Teknologi MARA
collection	UiTM Institutional Repository
language	English
advisor	Krasilnikova, Anna
topic	QP Physiology Particular diseases of the eye
spellingShingle	QP Physiology Particular diseases of the eye Zaukafali, Tajul Atiqah Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
description	Glaucoma is the major cause of an irreversible blindness worldwide and it is commonly associated with an elevation of intraocular pressure. ACE inhibitors have been shown to have ocular hypotensive effect in animals and human subjects. The aim of the study was to evaluate the ocular hypotensive effect and the effect on attenuation of trabecular meshwork remodelling by topical application of ACE inhibitor, enalaprilat dehydrate in chronic steroid-induced ocular hypertensive rat model. Ocular hypertension was developed in normotensive Sprague Dawley rats (100-120g) of either sex by topical instillation of dexamethasone 0.1%, 2 times daily for 36 days. The rats that developed more than 25% rise in IOP were considered ocular hypertensive.
format	Thesis
qualification_level	Bachelor degree
author	Zaukafali, Tajul Atiqah
author_facet	Zaukafali, Tajul Atiqah
author_sort	Zaukafali, Tajul Atiqah
title	Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
title_short	Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
title_full	Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
title_fullStr	Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
title_full_unstemmed	Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali
title_sort	role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / tajul atiqah zaulkafali
granting_institution	Universiti Teknologi MARA (UiTM)
granting_department	Faculty of Medicine
publishDate	2013
url	https://ir.uitm.edu.my/id/eprint/72215/1/72215.pdf
_version_	1794191892133445632

Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rat / Tajul Atiqah Zaulkafali

Similar Items