Azadirachta excelsa ameliorates hyperglycaemia and diabetes-associated learning and memory impairments in streptozotocin-induced type 1 diabetic rats / Noor Syaffinaz Noor Mohamad Zin
The decline in learning and memory functions manifested by diabetes mellitus is develops with the association of hyperglycaemia-induced oxidative stress. The current hypoglycaemic agent, including metformin causes many adverse effects that have raised the trend of traditional plant consumption in am...
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| Format: | Thesis |
| Language: | English |
| Published: |
2018
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| Online Access: | https://ir.uitm.edu.my/id/eprint/92917/1/92917.pdf |
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| Summary: | The decline in learning and memory functions manifested by diabetes mellitus is develops with the association of hyperglycaemia-induced oxidative stress. The current hypoglycaemic agent, including metformin causes many adverse effects that have raised the trend of traditional plant consumption in ameliorating diabetes. Azadirachta excelsa leaves extract causes the reduction of fasting blood glucose (FBG), yet its effect towards oxidative stress, the other biochemical and histological changes in the brain as well as the learning and memory functions remain to be analysed further. |
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