The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications

A Co-Cr-Mo (ASTM F-75) alloy is generally used because of their mechanical properties, good wear and corrosion resistance as well as biocompatibility. In order to obtain chemical similarity and interfacial bond form between implanted biomaterials and living tissue, addition of Hydroxyapatite (HAP) i...

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Main Author:	Rohaya, Abdul Malek
Format:	Thesis
Language:	English
Subjects:	Alloy Biomaterial Hydroxyapatite (HAP) Natural materials Corrosion
Online Access:	http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/1/p.%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/2/Full%20Text.pdf
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spelling	my-unimap-128482011-06-28T09:39:18Z The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications Rohaya, Abdul Malek A Co-Cr-Mo (ASTM F-75) alloy is generally used because of their mechanical properties, good wear and corrosion resistance as well as biocompatibility. In order to obtain chemical similarity and interfacial bond form between implanted biomaterials and living tissue, addition of Hydroxyapatite (HAP) is required. This study has focused on a research on F-75 alloy mixed with HAP fabricated by powder metallurgy (P/M) technique. The effect of HAP addition ranging between 2 and 10 wt.% on biocompatibility, physical and mechanical properties were examined. During compaction, 500MPa of pressure was applied using uniaxial press machine. The samples were sintered into tube furnace at 1100˚C in argon atmosphere. The samples with dimensions of approximately 5mm in thickness and 19mm in diameter were produced. To analyse the result, the reference sample (F-75 alloy without HAP powder) and composites were compared. All the samples were tested to determine shrinkage, grain size, bulk density, apparent porosity, microhardness and corrosion test. For biocompatibility (corrosion test), all samples were immersed into simulated body fluid of 0.9% sodium chloride solution at 37˚C in 6-week duration. Every interval of 48 hours, the weight loss per area was recorded. By increasing amount of HAP, it is noticed that the composites were less shrink and grain size getting larger compared to the reference sample. The largest grain size was obtained for composite consists of 10 wt.% of HAP (32.56μm) meanwhile the smallest grain size was obtained for reference sample (21.43μm). These results are inversely proportional to the decreasing value of bulk density and microhardness. The result of apparent porosity closely to 30% is obtained due to the increasing amount of HAP. Higher result of apparent porosity is required for bone ingrowth purposes. For microstructure analysis, the composites microstructure showed agglomeration of HAP and pores scattered on the composite surface. Meanwhile, biocompatibility test has indicated that the corrosion rate are increasing due to addition of HAP except for composite that consists of 2 wt.% of HAP which has the lowest corrosion rate among others (2.53mpy). The possibilities that contribute to the increasing of corrosion rate as a function of HAP addition are; the formation of general attack and pitting between matrix and electrochemical solution used. Besides, the formation of apatite layer can be clearly seen on the composite surface as predicted. According to the results, composite contains 6 wt.% of HAP shows an interesting result for apparent porosity and corrosion resistance that can be correlated to the requirement of biomaterial applications. Universiti Malaysia Perlis 2010 Thesis en http://dspace.unimap.edu.my/123456789/12848 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/1/p.%201-24.pdf 7af872e138a6948e1516d28896b17947 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/2/Full%20Text.pdf 8c633299b7b2a2dd6ef2b1d852a2f1c5 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/3/license.txt 066f6a4b64a3bf77486a532368a14e91 Alloy Biomaterial Hydroxyapatite (HAP) Natural materials Corrosion School of Materials Engineering
institution	Universiti Malaysia Perlis
collection	UniMAP Institutional Repository
language	English
topic	Alloy Biomaterial Hydroxyapatite (HAP) Natural materials Corrosion
spellingShingle	Alloy Biomaterial Hydroxyapatite (HAP) Natural materials Corrosion Rohaya, Abdul Malek The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
description	A Co-Cr-Mo (ASTM F-75) alloy is generally used because of their mechanical properties, good wear and corrosion resistance as well as biocompatibility. In order to obtain chemical similarity and interfacial bond form between implanted biomaterials and living tissue, addition of Hydroxyapatite (HAP) is required. This study has focused on a research on F-75 alloy mixed with HAP fabricated by powder metallurgy (P/M) technique. The effect of HAP addition ranging between 2 and 10 wt.% on biocompatibility, physical and mechanical properties were examined. During compaction, 500MPa of pressure was applied using uniaxial press machine. The samples were sintered into tube furnace at 1100˚C in argon atmosphere. The samples with dimensions of approximately 5mm in thickness and 19mm in diameter were produced. To analyse the result, the reference sample (F-75 alloy without HAP powder) and composites were compared. All the samples were tested to determine shrinkage, grain size, bulk density, apparent porosity, microhardness and corrosion test. For biocompatibility (corrosion test), all samples were immersed into simulated body fluid of 0.9% sodium chloride solution at 37˚C in 6-week duration. Every interval of 48 hours, the weight loss per area was recorded. By increasing amount of HAP, it is noticed that the composites were less shrink and grain size getting larger compared to the reference sample. The largest grain size was obtained for composite consists of 10 wt.% of HAP (32.56μm) meanwhile the smallest grain size was obtained for reference sample (21.43μm). These results are inversely proportional to the decreasing value of bulk density and microhardness. The result of apparent porosity closely to 30% is obtained due to the increasing amount of HAP. Higher result of apparent porosity is required for bone ingrowth purposes. For microstructure analysis, the composites microstructure showed agglomeration of HAP and pores scattered on the composite surface. Meanwhile, biocompatibility test has indicated that the corrosion rate are increasing due to addition of HAP except for composite that consists of 2 wt.% of HAP which has the lowest corrosion rate among others (2.53mpy). The possibilities that contribute to the increasing of corrosion rate as a function of HAP addition are; the formation of general attack and pitting between matrix and electrochemical solution used. Besides, the formation of apatite layer can be clearly seen on the composite surface as predicted. According to the results, composite contains 6 wt.% of HAP shows an interesting result for apparent porosity and corrosion resistance that can be correlated to the requirement of biomaterial applications.
format	Thesis
author	Rohaya, Abdul Malek
author_facet	Rohaya, Abdul Malek
author_sort	Rohaya, Abdul Malek
title	The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
title_short	The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
title_full	The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
title_fullStr	The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
title_full_unstemmed	The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications
title_sort	effect of hap addition on properties f-75 alloy fabricated via p/m 6 for biomaterial applications
granting_institution	Universiti Malaysia Perlis
granting_department	School of Materials Engineering
url	http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/1/p.%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/12848/2/Full%20Text.pdf
_version_	1747836761924435968

The effect of HAP addition on properties F-75 alloy fabricated via P/M 6 for biomaterial applications

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