A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting

A digital artery disease in the upper extremity is uncommon to happen but the revascularization procedure is still needed. As action taken, the surgical vein bypassing or vein interposition is performed. However, one or more internal diameters of the applied Reverse Saphenous Vein Graft (RSVG) are...

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Main Author: Muhd Nur Rahman, Yahya
Format: Thesis
Language:English
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Online Access:http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/1/p.1-24.pdf
http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/2/Full%20text.pdf
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spelling my-unimap-441982016-11-29T08:06:40Z A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting Muhd Nur Rahman, Yahya Dr. Shahriman Abu Bakar A digital artery disease in the upper extremity is uncommon to happen but the revascularization procedure is still needed. As action taken, the surgical vein bypassing or vein interposition is performed. However, one or more internal diameters of the applied Reverse Saphenous Vein Graft (RSVG) are blocked and severely narrowed due to the irregular geometry formation such as internal diameter mismatched and over the length kink after the revascularization. In previous researches, the irregular geometry formation, the size discrepancy and bent in the vessel caused the abnormal blood flow and initiated the thrombosis. Furthermore, their previous works were also supported by clinical theory. The objective of this study is to investigate the effect of the blood flow on internal diameter mismatched and over the length kink of the RSVG models that relates to their long term survival. A Three-Dimensional Computational Fluid Dynamic (3D CFD) method is employed to investigate the velocity, the pressure gradient and the Wall Shear Stress (WSS) on ideal straight and irregular geometry of the RSVG models. For this research, the pulsatile laminar blood flow demonstrates non-hydraulically flow in irregular geometry of the vein graft models compared to an ideal straight model even in a steady state laminar blood flow test. As a conclusion, the results showed high value in the velocity, the pressure gradient and the WSS in the mismatch problem but low value in the velocity, the pressure gradient and the WSS in the over length kink problem. Any abnormal blood flow behavior will initiate the formation of the thrombosis and reduce the vein graft survival. Universiti Malaysia Perlis (UniMAP) 2014 Thesis en http://dspace.unimap.edu.my:80/xmlui/handle/123456789/44198 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/1/p.1-24.pdf a6d9d15a3a890a3307c0dbe9b4372356 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/2/Full%20text.pdf 29168420434ddd24a6c73a5faf6f5c9c http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/3/license.txt 8a4605be74aa9ea9d79846c1fba20a33 Digital artery disease Microvascular vein grafting Fluid mechanics Computational fluid dynamics (CFD) Reverse Saphenous Vein Graft (RSVG) School of Mechatronic Engineering
institution Universiti Malaysia Perlis
collection UniMAP Institutional Repository
language English
advisor Dr. Shahriman Abu Bakar
topic Digital artery disease
Microvascular vein grafting
Fluid mechanics
Computational fluid dynamics (CFD)
Reverse Saphenous Vein Graft (RSVG)
spellingShingle Digital artery disease
Microvascular vein grafting
Fluid mechanics
Computational fluid dynamics (CFD)
Reverse Saphenous Vein Graft (RSVG)
Muhd Nur Rahman, Yahya
A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
description A digital artery disease in the upper extremity is uncommon to happen but the revascularization procedure is still needed. As action taken, the surgical vein bypassing or vein interposition is performed. However, one or more internal diameters of the applied Reverse Saphenous Vein Graft (RSVG) are blocked and severely narrowed due to the irregular geometry formation such as internal diameter mismatched and over the length kink after the revascularization. In previous researches, the irregular geometry formation, the size discrepancy and bent in the vessel caused the abnormal blood flow and initiated the thrombosis. Furthermore, their previous works were also supported by clinical theory. The objective of this study is to investigate the effect of the blood flow on internal diameter mismatched and over the length kink of the RSVG models that relates to their long term survival. A Three-Dimensional Computational Fluid Dynamic (3D CFD) method is employed to investigate the velocity, the pressure gradient and the Wall Shear Stress (WSS) on ideal straight and irregular geometry of the RSVG models. For this research, the pulsatile laminar blood flow demonstrates non-hydraulically flow in irregular geometry of the vein graft models compared to an ideal straight model even in a steady state laminar blood flow test. As a conclusion, the results showed high value in the velocity, the pressure gradient and the WSS in the mismatch problem but low value in the velocity, the pressure gradient and the WSS in the over length kink problem. Any abnormal blood flow behavior will initiate the formation of the thrombosis and reduce the vein graft survival.
format Thesis
author Muhd Nur Rahman, Yahya
author_facet Muhd Nur Rahman, Yahya
author_sort Muhd Nur Rahman, Yahya
title A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
title_short A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
title_full A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
title_fullStr A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
title_full_unstemmed A computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
title_sort computational fluid dynamic analysis of prolonging survival in the microvascular vein grafting
granting_institution Universiti Malaysia Perlis (UniMAP)
granting_department School of Mechatronic Engineering
url http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/1/p.1-24.pdf
http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/44198/2/Full%20text.pdf
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