Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications

In this study, bio-glass 45S5 powder was added into the mixture of Mg-Zn powders to produce biocomposite using powder metallurgy method for biomedical applications. The bio-glass composition was varied from 0, 5, 10, 15, 20, 25, to 30 wt. %. The objective of this works is to study the effect of b...

Full description

Saved in:

Bibliographic Details
Format:	Thesis
Language:	English
Subjects:	Biomedical materials Magnesium Mg-Zn powders Powder metallurgy Biocomposite materials
Online Access:	http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/2/Full%20text.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-unimap-72277
record_format	uketd_dc
spelling	my-unimap-722772021-09-30T03:12:12Z Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications Shamsul Baharin, Jamaludin, Prof. Dr. In this study, bio-glass 45S5 powder was added into the mixture of Mg-Zn powders to produce biocomposite using powder metallurgy method for biomedical applications. The bio-glass composition was varied from 0, 5, 10, 15, 20, 25, to 30 wt. %. The objective of this works is to study the effect of bio-glass addition into Mg-Zn based biomaterials in terms of physical, mechanical, corrosion resistance and bioactivity properties. Optical microscope, Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS) and X-Ray Diffraction (XRD) were used to characterize the microstructure and phases present in the composites. Microstructure result shows that bio-glass was distributed in the matrix Mg-Zn. EDS results show that Zn has not completely diffuse into the Mg matrix due to the effect of processing parameter. There is no evidence of bio-glass diffusion into the matrix. XRD diffraction patterns of as sintered samples show expected peak of Mg in all samples. Properties such as density and compressive strength were determined using the pycnometer and Instron machine respectively. Density of the composite was compared with the theoretical value and the result trends indicated that the density has increased as the amount of bio-glass increased. The trends are valid for the true, theoretical, and bulk densities. Increment of densities value could be subjected to the filling of interparticles spacing by bio-glass. However, the total porosity also increased as the bio-glass amount increased. It could be attributed to the segregation of bio-glass particles. As the amount of bio-glass increase, more bio-glass segregate and leads to bigger size of bio-glass inclusion size inside the composite. Since no reaction between magnesium and bio-glass, the bigger the size of bio-glass inclusions, the larger the voids form at the interface, which will eventually give raise to total porosity results. The compressive strength shows that as the amount of bio-glass increased, the compressive strength of the composites decreased. This also could be attributed to the voids left at the interface of bio-glass and matrix which acts as crack initiators. In vitro test was conducted, in which samples were immersed in Simulated Body Fluid (SBF) to determine the corrosion rate and bioactivity of the composites. The results showed that corrosion rate of the samples decreases with increasing content of bio-glass. The accumulation of corrosion products, alongside with the formation of apatite layer retarded the corrosion process. The apatite layer that used to indicate the bioactivity was also traced on the surface of composites. The apatite layer formed has a lower value of Ca/P ratio compared to the ideal crystalline hydroxyapatite, however it is still compliant with biomaterials requirement Universiti Malaysia Perlis (UniMAP) Thesis en http://dspace.unimap.edu.my:80/xmlui/handle/123456789/72277 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/3/license.txt 8a4605be74aa9ea9d79846c1fba20a33 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/1/Page%201-24.pdf 6d5ab072d7cb77a3d4a93b547d97780b http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/2/Full%20text.pdf fff38c3a620a31c956d5c70007a97161 Universiti Malaysia Perlis (UniMAP) Biomedical materials Magnesium Mg-Zn powders Powder metallurgy Biocomposite materials School of Materials Engineering
institution	Universiti Malaysia Perlis
collection	UniMAP Institutional Repository
language	English
advisor	Shamsul Baharin, Jamaludin, Prof. Dr.
topic	Biomedical materials Magnesium Mg-Zn powders Powder metallurgy Biocomposite materials
spellingShingle	Biomedical materials Magnesium Mg-Zn powders Powder metallurgy Biocomposite materials Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
description	In this study, bio-glass 45S5 powder was added into the mixture of Mg-Zn powders to produce biocomposite using powder metallurgy method for biomedical applications. The bio-glass composition was varied from 0, 5, 10, 15, 20, 25, to 30 wt. %. The objective of this works is to study the effect of bio-glass addition into Mg-Zn based biomaterials in terms of physical, mechanical, corrosion resistance and bioactivity properties. Optical microscope, Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS) and X-Ray Diffraction (XRD) were used to characterize the microstructure and phases present in the composites. Microstructure result shows that bio-glass was distributed in the matrix Mg-Zn. EDS results show that Zn has not completely diffuse into the Mg matrix due to the effect of processing parameter. There is no evidence of bio-glass diffusion into the matrix. XRD diffraction patterns of as sintered samples show expected peak of Mg in all samples. Properties such as density and compressive strength were determined using the pycnometer and Instron machine respectively. Density of the composite was compared with the theoretical value and the result trends indicated that the density has increased as the amount of bio-glass increased. The trends are valid for the true, theoretical, and bulk densities. Increment of densities value could be subjected to the filling of interparticles spacing by bio-glass. However, the total porosity also increased as the bio-glass amount increased. It could be attributed to the segregation of bio-glass particles. As the amount of bio-glass increase, more bio-glass segregate and leads to bigger size of bio-glass inclusion size inside the composite. Since no reaction between magnesium and bio-glass, the bigger the size of bio-glass inclusions, the larger the voids form at the interface, which will eventually give raise to total porosity results. The compressive strength shows that as the amount of bio-glass increased, the compressive strength of the composites decreased. This also could be attributed to the voids left at the interface of bio-glass and matrix which acts as crack initiators. In vitro test was conducted, in which samples were immersed in Simulated Body Fluid (SBF) to determine the corrosion rate and bioactivity of the composites. The results showed that corrosion rate of the samples decreases with increasing content of bio-glass. The accumulation of corrosion products, alongside with the formation of apatite layer retarded the corrosion process. The apatite layer that used to indicate the bioactivity was also traced on the surface of composites. The apatite layer formed has a lower value of Ca/P ratio compared to the ideal crystalline hydroxyapatite, however it is still compliant with biomaterials requirement
format	Thesis
title	Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
title_short	Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
title_full	Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
title_fullStr	Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
title_full_unstemmed	Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
title_sort	characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications
granting_institution	Universiti Malaysia Perlis (UniMAP)
granting_department	School of Materials Engineering
url	http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72277/2/Full%20text.pdf
_version_	1747836862431494144

Characterization and in-vitro activity of powder metallurgy magnesium-zinc/bioglass composite for biomedical applications

Similar Items