Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection
Lab-on-chip fabricated with one-dimensional nanowires offer excellent electrical properties where bio molecular analysis at very low concentrations is becoming increasingly relevant for medical and research communities. Good number of techniques and promising results has been established for detecti...
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my-unimap-727042021-11-18T08:21:28Z Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection Uda, Hashim, Prof. Dr. Lab-on-chip fabricated with one-dimensional nanowires offer excellent electrical properties where bio molecular analysis at very low concentrations is becoming increasingly relevant for medical and research communities. Good number of techniques and promising results has been established for detecting small concentrations; however, for high-throughput measurements and label-free detection are still area of fresh investigation. Many research groups have reported high level of bio recognition by using semiconductor nanowire. The semiconductors silicon nanowire biosensor utilizes a Nano wire between two conducting materials. The nanowire has its atoms concentrated on its surface. Thus, any small changes in the charges present on the nanowire will cause a change in the flow of current. In this thesis, a simulation study coupled with experimental approach to explain the change in wire surface behavior as function of the surface charge. The linear behavior of the conductivity to increase the sensitivity of a semiconducting nanowire biosensor is ascertained. The silicon wire should be between 5 to 20nm to allow mean distance between atoms, the oxide should be as thin as possible for optimum surface integrity, and the functional layer should be thin and have a high dielectric constant. The ionic concentration of the electrolyte should be kept low in order to have a large Debye screening length. To confirm these theoretical results, Silicon nanowire of ≈ 15nm was fabricated using conventional photolithography coupled with dry etching process. To determine the capability of the device, it subjected to various pH values and to achieve this, the device is being operated based on the principle of Field Effect Transistor (FET). The surface of the device is hole dominated (p-type material). Universiti Malaysia Perlis (UniMAP) Thesis en http://dspace.unimap.edu.my:80/xmlui/handle/123456789/72704 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/3/license.txt 8a4605be74aa9ea9d79846c1fba20a33 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/1/Page%201-24.pdf b606769981c62849d9e074454419b298 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/2/Full%20text.pdf 184474f436bf8434186a75f1beb3b702 http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/4/Tijani%20Adam.pdf c98bc8e5dd965cf97055683bd3af54ff Universiti Malaysia Perlis (UniMAP) Microfluids Nanowires Biosensors Nano Lab-On-Chip Nanotechnology Institute of Nano Electronic Engineering |
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Universiti Malaysia Perlis |
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UniMAP Institutional Repository |
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English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English |
advisor |
Uda, Hashim, Prof. Dr. Umi Fazara, Md. Ali, Dr. Mohamad Halim, Adb. Wahid, Dr. Anuar, Mat Safar, Dr. Ir. Mohd Shukry, Abdul Majid, Assoc. Prof. Ir. Dr. Zainor Ridzuan, Yahya. Dr. Salmah, Husseinsyah, Assoc. Prof. Ir. Dr. Salmah, Husseinsyah, Assoc. Prof. Ir. Dr. Mohd Irwan, Yusoff,Dr. Mohd Azrik, Roslan, Dr. Kamarudin, Husin, Datuk. Prof. Emeritus Dr. Muzamir, Isa, Assoc. Prof. Dr. Mohd Nashrul Fazli, Mohd Nasir, Dr. Nik Noriman, Zulkepli, Dr. Mohd Najmuddin, Mohd Hassan, Assoc. Prof. dr. Shahrul Nizam, Yaakob, Assoc. Prof. Dr. Muhammad Asri, Idris, Dr. Muhammad Faiq, Abdullah Mohd Noor, Ahmad, Dr. Omg, Bi Lynn, Dr. Azwan Iskandar, Azmi, Dr. Zarina, Zakaria, Dr. Khairul Azwan, Ismail, Assoc. Prof. Dr. Syed Alwee Al Junid, Syed Junid, Prof. Dr. Muhammad Zaini, Ahmad, Dr. Mohd Noor, Ahmad, Prof. Dr. Irwana Nainggolan, Dr. Marliza, Mostapha@Zakaria Nashrul Fazli, Mohd Nasir, Dr. Sam Sung, Ting, Dr. Sabira, Khatun, Prof. Dr. Norainiza, Saud, Dr. Wan Zuki Azman, Wan Muhamad Kamarudin, Hussin, Datuk Prof. Dr. Khor, Shing Fhan Hariharan, Muthusamy, Dr. Wan Khairunizam, Wan Ahmad, Assoc. Prof. Dr. Rozyanty, Rahman, Dr. Ali Yeon, Md. Shakaff, Prof. Dr. Abdullah, Chik, Assoc. Prof. Ali Yeon, Md. Shakaff, Prof. Dr. Ali Yeon, Md. Shakaff, Prof. Dr. R. Badlishah, Ahmad, Prof. Ir. Dr. Md. Aminul, Islam, Prof. Dr. Anuar, Mat Safar, Prof. Ir. Dr. Rozyanty, Rahman, Dr. Ragunathan, Santiagoo, Dr. Sharifah Shahnaz, Syed Bakar, Dr. Yusoff, Mashor, Prof. Dr. Mohd Shukry, Abdul Majid, Assoc. Prof. Ir. Dr. Mohd Khairuddin, Md. Arshad, Ir. Dr. Mohd Mustafa Al Bakri, Abdullah, Assoc. Prof. Dr. Mohd Afendi, Rojan, Dr. Rosni, Bakar, Prof. Dr. Uda, Hashim, Prof. Dr. Md. Aminul, Islam, Assoc. Prof. Dr. Sara Yasina, Yusuf, Dr. Kamarudin, Hussin, Prof. Emeritus Dr. Abadal-Salam Taha, Hussain, Dr. Mohd Zulham Affandi, Mohd Zahid Muhammad Irwanto, Misrun, Dr. Teh, Pei Leng, Dr. Rosni, Bakar, Prof. Dr. Vithyacharan, Retnasamy, Dr. Khairul Azwan, Ismail, Assoc. Prof. Dr. Mohd Khairuddin, Md. Arshad, Ir. Dr. Sam Sung, Ting, Dr. Nor Fauziah, Zainudin Norainiza, Saud, Dr. Zuraidawani, Che Daud, Dr. Phak Len, Eh Kan, Dr. Mohd Faizal, Jamlos, Assoc. Prof. Dr. Mohammad Iqbal, Omar, Assoc. Prof. Dr. Mohd Shukry, Abdul Majid, Dr. Mohd Shukry, Abdul Majid, Dr. Muhammad Syarhabil, Ahmad, Assoc. Prof. Dr. Sam Sung, Ting, Dr. Norainiza, Saud, Dr. Mohd Firdaus, Omar, Dr. Mohd Faizal, Jamlos, Assoc. Prof. Ir. Dr. Md. Mijanur, Rahman, Dr. Nik Noriman, Zulkepli, Dr. R. Badlishah, Ahmad, Prof. Dr. Ali Yeon, Md. Shakaff, Prof. Dr. Hilal Adnan, Fadhil Che Mohd Ruzaidi, Ghazali, Assoc. Prof. Nik Noriman, Zulkepli, Dr. Salmah, Husseinsyah, Assoc. Prof. Ir. Dr. Shafriza Nisha, Basah, Dr. Kahtan S., Mohammed, Dr. Hariharan, Muthusamy, Dr. Ali Yeon, Md. Shakaff, Prof. Dr. Hariharan, Muthusamy, Dr. Ali Yeon, Md. Shakaff, Prof. Dr. Abdul Hamid, Adom, Prof. Dr. Wan Khairunizam, Wan Ahmad, Assoc. Prof. Dr. Hariharan, Muthusamy, Dr. Salmah, Husseinsyah, Assoc. Prof. Ir. Dr. Kahtan S., Mohammed, Dr. |
topic |
Microfluids Nanowires Biosensors Nano Lab-On-Chip Nanotechnology Hematite Solar energy Photo-Anode film Photo-electrochemical (PEC) Photo-Anode film -- Design and construction Hydrogen (H2) Optical fiber communication Optical communication Optical data processing Laser communication systems Optical switches Pressure transducers Natural rubber FBG sensor Microelectromechanical systems Optical fiber communication Fibrous composites Glass fibers Composite materials Napier fibres Natural fiber Spline theory Information visualization Curves Surfaces Computer graphics Three-dimensional imaging Shapes Thermoplastics Polyethylene Polypropylene Polymers Recycled polypropylene (rPP) Recycled high density polyethylene (rHDPE) Polymer blends Thermoplastic composites Thermoplastics Fillers (Materials) Biocomposite Cocoa pod husk (CPH) Polypropylene (PP) Photovoltaic power systems Renewable energy sources Heat -- Transmission Gas air conditioning Photovoltaic (PV) Cooling system Microgrids (Smart power grids) Microgrid Power sharing Central controller Fuzzy mathematics Fuzzy logic Kaolin Concrete masonry Bricks Geopolymer masonry brick Geopolymer Electric insulators and insulation Partial discharge (PD) Artificial neural network (ANN) Muscle EMG signals Electromyography (EMG) Body posture Solah Rubber -- Recycling Microfluids Microfluids Microfluids Recycled rubber blends Ethylene propylene diene monomer (EPDM) Recycled acrylonitrile butadiene rubber (rNBR) Greenhouse plants Wireless sensor networks Computer science Greenhouse -- Monitoring and management system Internet of Things (IoT) Microfluids Data encryption (Computer science) Cryptography Encryption Self-consolidating concrete Concrete Limestone powder Self-Compacting Concrete (SCC) Fisheries Fish feeds Catfish Fish Feed Nutrients African catfish (Clarias gariepinus) Polyanilines Nanofibers Ammonia Nanostructured polyaniline (PANI) Chemiresistor sensor Vehicular ad hoc networks (Computer networks) Vehicular Ad Hoc Networks (VANET) Networks Routing protocol Polymeric composites Fiber-reinforced plastics Hybrid composites Composites Hybrid Fibre-Reinforced Polymer (FRP) Cultivated mushroom Pleurotus Lyophilization Pleurotus pulmonarius Wound healing Wounds and injuries Hypertrophic scars Headgear Pressure garment Code division multiple access Optical communication Optical Code-Division Multiple-Access System (OCDMA) Noise Optical network Transformations (Mathematics) Differential equations Integral transforms Ordinary differential Equations (ODEs) Fuzzy Sumudu transform (FST) Fuzzy numbers Graphene Microfluids Antenna radiation patterns Antennas (Electronics) Graphene Oxide Chitosan Chitin Polyethylene oxide Graphite Detectors Composite materials Cellulose -- Biodegradation Coconut shell (CS) Biocomposite films Cellulose composites Biocomposites Tissue Scaffolds Tissue engineering Scaffolding Starch Dielectrics nHA/starch Biomedical engineering Biodegradable plastics Polyethylene Biocomposites Plastics Rambutan peel Blood sugar Diabetes Blood glucose Diabetic patient Ultra-wideband devices Solder and soldering Powder Metallurgy Sintering Soldering technology Solders Heuristic algorithms Routing protocols (Computer network protocols) Microfluids Arc Routing Problem Capacitated Arc Routing Problem (MCARP) Aggregates (Building materials) Inorganic Polymers Mud volcanoes Microfluids Geopolymers Lightweight aggregate Electrolytes Magnesium phosphate Dielectrics Liquid dielectrics Optical glass Hydrogel Body mass index (BMI) Obesity Speech recognition BMI prediction Face detection Emotion recognition Intelligent real-time facial expression recognition system -- Design and construction Intelligent real-time facial expression recognition system Polymeric composites Fibers Kenaf Hybrid composites Composites Natural fiber Swarm intelligence Robotics Odour Gas sensing Gas source localization Agricultural waste Citric acid Silica Oil palm ash Heat -- Transmission Fire detection Classifier Automatic Fire Detection Indoor Air Quality (IAQ) Harumanis mango Optical communication Harumanis Harumanis -- Quality inspection Machine Vision Detectors Phishing Network security Phishing Detection System Hotel industry Tourism management Brand image Advertisement Tourism -- Bangladesh Wireless communication systems Orthogonal Frequency-Division Multiplexing (OFDM) Wireless Foamed materials Polyurethanes Kenaf Polyurethane foam (PUF) Fibers Kenaf fibers Composites Natural fiber Polyethylene Palm kernel shell (PKS) Composites Thermoplastic Recycled acrylonitrile butadiene rubber (NBRr) Polypropylene (PP) Polyethylene Bedpan Thermoplastic Polyvinyl Chloride Polymer Thalassemia Red blood cells (RBC) Image enhancement Blood disease Glass fibers Glass fibre reinforced epoxy (GRE) Pipes Composites Composite pipe Wired glove system -- Design and construction Wired glove system GloveMAP Dataglove Power rectifier Power Rectifier (P-i-N rectifier) Diode Polymeric composites Geopolymers Kaolin Coating Geopolymer coating White clay Biomedical materials Hydrothermal Bonded T-Joint Adhesive joint Hydrothermal effect Organizational performance Banking institutions -- Jordan Accounting information systems (AIS) Jordanian banking sector Nanoparticles Escherichia coli Sensors Escherichia coli O157:H7 (E.coli O157:H7) -- Detection Stock exchange Earnings management (EM) Jordanian capital market Corporate governance Electrolytic reduction Carbon dioxide Formate Cathode Soil stabilization Soil mechanics Geopolymerization Photovoltaic power generation Renewable resource integration Energy development Renewable energy Photovoltaic Maximum Power Point Tracking (MPPT) Concrete beams Reinforced concrete Reinforced concrete construction Concrete Ultra High Performance Concrete (UHPC) Photovoltaic power systems Wind power Renewable energy sources Photovoltaic cooling system Wind power generation Epoxy resins Foam rubber Rubber Toluene Epoxy Polymer foam Human resource management Banking institutions Banking institutions -- Jordan Organizational behavior Total quality management (TQM) Organizational performance Blood-vessels Stenosis Arteries -- Stenosis Atherosclerosis Cardiovascular system Microelectromechanical systems Injection molding of plastics Concrete -- Expansion and contraction Materials -- Mechanical properties Metal oxide semiconductor field-effect transistors Ultra-shallow junction Junctionless Transistor Biodegradable plastics Biodegradable products Polyolefins Sewage disposal Microfluids Cerbera Sea Mango Solder and soldering Tin alloys SnPb solders Magnesium alloys Powder Metallurgy Digital images Image analysis Field programmable gate arrays Antenna arrays MIMO systems Bacteria detection Electric nose Diabetic Fibrous composites Thermoplastic composites Thermoplastics Composite materials Composite Materials Glass fibers Fibrous composites GRE composite pipes Antifungal agents Phytochemicals Cerbera Crops -- Postharvest losses -- Prevention Fibers Polyethylene Polylactic acid Solder and soldering Carbon composites Tin Copper Powder Metallurgy Materials -- Mechanical properties Composite materials Thermoplastics Reinforced plastics Rice husk Linear Low Density Polyethylene (LLDPE) Ground penetrating radar Microwave imaging Imaging systems Radar Orthogonal frequency division multiplexing Digital modulation Wireless LANs Wireless communication systems Artificial joints Ultrahigh molecular weight polyethylene Polyethylene Fillers (Materials) Polymeric composites Photovoltaic power systems PIC microcontrollers Renewable energy sources Pattern recognition systems Capsicum annuum Image processing Image processing -- Digital techniques Herbs Code division multiple access Telecommunication systems. Optical communication Computer network Solder and soldering Hot air solder levelling (HASL) Solder Solder joint Carbonization Bamboo activated carbon (AC) Gigantochloa Scortechiini (Bamboo) Carbonized bamboo Activated carbon (AC) Composite materials Protein Electron beam Chitin Corncorb Joints -- Range of motion Leg Tracking (Engineering) Eye tracking Friction stir welding Aluminum Copper alloys Alloys Crying in infants Signal processing Neural networks (Computer science) Wavelets (Mathematics) Wigner distribution Mobile robots Gas distribution Smell Emotion recognition Emotional intelligence Facial expression Indoor air quality Detectors Infrared array detectors Brain-computer interfaces Electroencephalography Chairs for people with disabilities Artificial intelligence Thermoelectric cooling Hybrid Thermoelectric Refrigerator (H-TER) Vaccines carrier Facial expression Emotion recognition Pattern recognition systems Human-computer interaction Composite materials Protein Fillers (Materials) Polyethylene Polylactic acid Nypa palm Metals -- Microstructure Materials -- Mechanical properties Metals -- Mechanical properties Powder metallurgy |
spellingShingle |
Microfluids Nanowires Biosensors Nano Lab-On-Chip Nanotechnology Hematite Solar energy Photo-Anode film Photo-electrochemical (PEC) Photo-Anode film -- Design and construction Hydrogen (H2) Optical fiber communication Optical communication Optical data processing Laser communication systems Optical switches Pressure transducers Natural rubber FBG sensor Microelectromechanical systems Optical fiber communication Fibrous composites Glass fibers Composite materials Napier fibres Natural fiber Spline theory Information visualization Curves Surfaces Computer graphics Three-dimensional imaging Shapes Thermoplastics Polyethylene Polypropylene Polymers Recycled polypropylene (rPP) Recycled high density polyethylene (rHDPE) Polymer blends Thermoplastic composites Thermoplastics Fillers (Materials) Biocomposite Cocoa pod husk (CPH) Polypropylene (PP) Photovoltaic power systems Renewable energy sources Heat -- Transmission Gas air conditioning Photovoltaic (PV) Cooling system Microgrids (Smart power grids) Microgrid Power sharing Central controller Fuzzy mathematics Fuzzy logic Kaolin Concrete masonry Bricks Geopolymer masonry brick Geopolymer Electric insulators and insulation Partial discharge (PD) Artificial neural network (ANN) Muscle EMG signals Electromyography (EMG) Body posture Solah Rubber -- Recycling Microfluids Microfluids Microfluids Recycled rubber blends Ethylene propylene diene monomer (EPDM) Recycled acrylonitrile butadiene rubber (rNBR) Greenhouse plants Wireless sensor networks Computer science Greenhouse -- Monitoring and management system Internet of Things (IoT) Microfluids Data encryption (Computer science) Cryptography Encryption Self-consolidating concrete Concrete Limestone powder Self-Compacting Concrete (SCC) Fisheries Fish feeds Catfish Fish Feed Nutrients African catfish (Clarias gariepinus) Polyanilines Nanofibers Ammonia Nanostructured polyaniline (PANI) Chemiresistor sensor Vehicular ad hoc networks (Computer networks) Vehicular Ad Hoc Networks (VANET) Networks Routing protocol Polymeric composites Fiber-reinforced plastics Hybrid composites Composites Hybrid Fibre-Reinforced Polymer (FRP) Cultivated mushroom Pleurotus Lyophilization Pleurotus pulmonarius Wound healing Wounds and injuries Hypertrophic scars Headgear Pressure garment Code division multiple access Optical communication Optical Code-Division Multiple-Access System (OCDMA) Noise Optical network Transformations (Mathematics) Differential equations Integral transforms Ordinary differential Equations (ODEs) Fuzzy Sumudu transform (FST) Fuzzy numbers Graphene Microfluids Antenna radiation patterns Antennas (Electronics) Graphene Oxide Chitosan Chitin Polyethylene oxide Graphite Detectors Composite materials Cellulose -- Biodegradation Coconut shell (CS) Biocomposite films Cellulose composites Biocomposites Tissue Scaffolds Tissue engineering Scaffolding Starch Dielectrics nHA/starch Biomedical engineering Biodegradable plastics Polyethylene Biocomposites Plastics Rambutan peel Blood sugar Diabetes Blood glucose Diabetic patient Ultra-wideband devices Solder and soldering Powder Metallurgy Sintering Soldering technology Solders Heuristic algorithms Routing protocols (Computer network protocols) Microfluids Arc Routing Problem Capacitated Arc Routing Problem (MCARP) Aggregates (Building materials) Inorganic Polymers Mud volcanoes Microfluids Geopolymers Lightweight aggregate Electrolytes Magnesium phosphate Dielectrics Liquid dielectrics Optical glass Hydrogel Body mass index (BMI) Obesity Speech recognition BMI prediction Face detection Emotion recognition Intelligent real-time facial expression recognition system -- Design and construction Intelligent real-time facial expression recognition system Polymeric composites Fibers Kenaf Hybrid composites Composites Natural fiber Swarm intelligence Robotics Odour Gas sensing Gas source localization Agricultural waste Citric acid Silica Oil palm ash Heat -- Transmission Fire detection Classifier Automatic Fire Detection Indoor Air Quality (IAQ) Harumanis mango Optical communication Harumanis Harumanis -- Quality inspection Machine Vision Detectors Phishing Network security Phishing Detection System Hotel industry Tourism management Brand image Advertisement Tourism -- Bangladesh Wireless communication systems Orthogonal Frequency-Division Multiplexing (OFDM) Wireless Foamed materials Polyurethanes Kenaf Polyurethane foam (PUF) Fibers Kenaf fibers Composites Natural fiber Polyethylene Palm kernel shell (PKS) Composites Thermoplastic Recycled acrylonitrile butadiene rubber (NBRr) Polypropylene (PP) Polyethylene Bedpan Thermoplastic Polyvinyl Chloride Polymer Thalassemia Red blood cells (RBC) Image enhancement Blood disease Glass fibers Glass fibre reinforced epoxy (GRE) Pipes Composites Composite pipe Wired glove system -- Design and construction Wired glove system GloveMAP Dataglove Power rectifier Power Rectifier (P-i-N rectifier) Diode Polymeric composites Geopolymers Kaolin Coating Geopolymer coating White clay Biomedical materials Hydrothermal Bonded T-Joint Adhesive joint Hydrothermal effect Organizational performance Banking institutions -- Jordan Accounting information systems (AIS) Jordanian banking sector Nanoparticles Escherichia coli Sensors Escherichia coli O157:H7 (E.coli O157:H7) -- Detection Stock exchange Earnings management (EM) Jordanian capital market Corporate governance Electrolytic reduction Carbon dioxide Formate Cathode Soil stabilization Soil mechanics Geopolymerization Photovoltaic power generation Renewable resource integration Energy development Renewable energy Photovoltaic Maximum Power Point Tracking (MPPT) Concrete beams Reinforced concrete Reinforced concrete construction Concrete Ultra High Performance Concrete (UHPC) Photovoltaic power systems Wind power Renewable energy sources Photovoltaic cooling system Wind power generation Epoxy resins Foam rubber Rubber Toluene Epoxy Polymer foam Human resource management Banking institutions Banking institutions -- Jordan Organizational behavior Total quality management (TQM) Organizational performance Blood-vessels Stenosis Arteries -- Stenosis Atherosclerosis Cardiovascular system Microelectromechanical systems Injection molding of plastics Concrete -- Expansion and contraction Materials -- Mechanical properties Metal oxide semiconductor field-effect transistors Ultra-shallow junction Junctionless Transistor Biodegradable plastics Biodegradable products Polyolefins Sewage disposal Microfluids Cerbera Sea Mango Solder and soldering Tin alloys SnPb solders Magnesium alloys Powder Metallurgy Digital images Image analysis Field programmable gate arrays Antenna arrays MIMO systems Bacteria detection Electric nose Diabetic Fibrous composites Thermoplastic composites Thermoplastics Composite materials Composite Materials Glass fibers Fibrous composites GRE composite pipes Antifungal agents Phytochemicals Cerbera Crops -- Postharvest losses -- Prevention Fibers Polyethylene Polylactic acid Solder and soldering Carbon composites Tin Copper Powder Metallurgy Materials -- Mechanical properties Composite materials Thermoplastics Reinforced plastics Rice husk Linear Low Density Polyethylene (LLDPE) Ground penetrating radar Microwave imaging Imaging systems Radar Orthogonal frequency division multiplexing Digital modulation Wireless LANs Wireless communication systems Artificial joints Ultrahigh molecular weight polyethylene Polyethylene Fillers (Materials) Polymeric composites Photovoltaic power systems PIC microcontrollers Renewable energy sources Pattern recognition systems Capsicum annuum Image processing Image processing -- Digital techniques Herbs Code division multiple access Telecommunication systems. Optical communication Computer network Solder and soldering Hot air solder levelling (HASL) Solder Solder joint Carbonization Bamboo activated carbon (AC) Gigantochloa Scortechiini (Bamboo) Carbonized bamboo Activated carbon (AC) Composite materials Protein Electron beam Chitin Corncorb Joints -- Range of motion Leg Tracking (Engineering) Eye tracking Friction stir welding Aluminum Copper alloys Alloys Crying in infants Signal processing Neural networks (Computer science) Wavelets (Mathematics) Wigner distribution Mobile robots Gas distribution Smell Emotion recognition Emotional intelligence Facial expression Indoor air quality Detectors Infrared array detectors Brain-computer interfaces Electroencephalography Chairs for people with disabilities Artificial intelligence Thermoelectric cooling Hybrid Thermoelectric Refrigerator (H-TER) Vaccines carrier Facial expression Emotion recognition Pattern recognition systems Human-computer interaction Composite materials Protein Fillers (Materials) Polyethylene Polylactic acid Nypa palm Metals -- Microstructure Materials -- Mechanical properties Metals -- Mechanical properties Powder metallurgy Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
description |
Lab-on-chip fabricated with one-dimensional nanowires offer excellent electrical properties where bio molecular analysis at very low concentrations is becoming increasingly relevant for medical and research communities. Good number of techniques and promising results has been established for detecting small concentrations; however, for high-throughput measurements and label-free detection are still area of fresh investigation. Many research groups have reported high level of bio recognition by using semiconductor nanowire. The semiconductors silicon nanowire biosensor utilizes a Nano wire between two conducting materials. The nanowire has its atoms concentrated on its surface. Thus, any small changes in the charges present on the nanowire will cause a change in the flow of current. In this thesis, a simulation study coupled with experimental approach to explain the change in wire surface behavior as function of the surface charge. The linear behavior of the conductivity to increase the sensitivity of a semiconducting nanowire biosensor is ascertained. The silicon wire should be between 5 to 20nm to allow mean distance between atoms, the oxide should be as thin as possible for optimum surface integrity, and the functional layer should be
thin and have a high dielectric constant. The ionic concentration of the electrolyte should be kept low in order to have a large Debye screening length. To confirm these theoretical results, Silicon nanowire of ≈ 15nm was fabricated using conventional
photolithography coupled with dry etching process. To determine the capability of the device, it subjected to various pH values and to achieve this, the device is being operated based on the principle of Field Effect Transistor (FET). The surface of the
device is hole dominated (p-type material). |
format |
Thesis |
title |
Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
title_short |
Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
title_full |
Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
title_fullStr |
Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
title_full_unstemmed |
Development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
title_sort |
development of silicon nanowire lab-on-chip microfluidics integrated biosensor for low concentration bio-molecules detection |
granting_institution |
Universiti Malaysia Perlis (UniMAP) |
granting_department |
Institute of Nano Electronic Engineering |
url |
http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72704/4/Tijani%20Adam.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77067/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77067/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77067/4/Muhammad%20Hafiz%20A%20Rahim.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77081/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77081/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77081/4/Mohd%20Farizal.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77975/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77975/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77975/4/Siti%20Fatimah%20Harun.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72832/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72832/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72832/4/Mohd%20Ridzuan.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77083/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77083/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77083/4/Anas%20Khalaf.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77082/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77082/2/Full%20text.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/77082/4/Siti%20Mariam%20Atiqah.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72706/1/Page%201-24.pdf http://dspace.unimap.edu.my:80/xmlui/bitstream/123456789/72706/2/Full%20text.pdf 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