Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these vi...
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2001
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my-unimas-ir.165852023-11-21T05:21:20Z Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections 2001 Wang, Seok Mui RA Public aspects of medicine All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these viruses co-circulate. We have demonstrated that DENV and JEV have unique epitopes on the prM. By detecting prM specific IgG, it is possible to distinguish between DENV and JEV infection. Current approach used in seroanalysis of DENV and JEV infections is based on antigens derived from the whole viral antigens. 2001 Thesis http://ir.unimas.my/id/eprint/16585/ http://ir.unimas.my/id/eprint/16585/1/Wong%20Seok%20ft.pdf text en validuser masters Universiti Malaysia Sarawak, (UNIMAS) Institute of Health and Community Medicine. |
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Universiti Malaysia Sarawak |
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UNIMAS Institutional Repository |
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English |
topic |
RA Public aspects of medicine |
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RA Public aspects of medicine Wang, Seok Mui Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
description |
All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these viruses co-circulate. We have demonstrated that DENV and JEV have unique epitopes on the prM. By detecting prM specific IgG, it is possible to distinguish between DENV and JEV infection. Current approach used in seroanalysis of DENV and JEV infections is based on antigens derived from the whole viral antigens. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Wang, Seok Mui |
author_facet |
Wang, Seok Mui |
author_sort |
Wang, Seok Mui |
title |
Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
title_short |
Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
title_full |
Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
title_fullStr |
Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
title_full_unstemmed |
Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections |
title_sort |
cloning and expression of prm and it's use to distinguish host immune responses against dengue virus and japanese encephalitis virus infections |
granting_institution |
Universiti Malaysia Sarawak, (UNIMAS) |
granting_department |
Institute of Health and Community Medicine. |
publishDate |
2001 |
url |
http://ir.unimas.my/id/eprint/16585/1/Wong%20Seok%20ft.pdf |
_version_ |
1783728199316799488 |