Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections

All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these vi...

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Main Author:	Wang, Seok Mui
Format:	Thesis
Language:	English
Published:	2001
Subjects:	RA Public aspects of medicine
Online Access:	http://ir.unimas.my/id/eprint/16585/1/Wong%20Seok%20ft.pdf
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id	my-unimas-ir.16585
record_format	uketd_dc
spelling	my-unimas-ir.165852023-11-21T05:21:20Z Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections 2001 Wang, Seok Mui RA Public aspects of medicine All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these viruses co-circulate. We have demonstrated that DENV and JEV have unique epitopes on the prM. By detecting prM specific IgG, it is possible to distinguish between DENV and JEV infection. Current approach used in seroanalysis of DENV and JEV infections is based on antigens derived from the whole viral antigens. 2001 Thesis http://ir.unimas.my/id/eprint/16585/ http://ir.unimas.my/id/eprint/16585/1/Wong%20Seok%20ft.pdf text en validuser masters Universiti Malaysia Sarawak, (UNIMAS) Institute of Health and Community Medicine.
institution	Universiti Malaysia Sarawak
collection	UNIMAS Institutional Repository
language	English
topic	RA Public aspects of medicine
spellingShingle	RA Public aspects of medicine Wang, Seok Mui Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
description	All flaviviruses share common epitopes on the envelope protein (E) that results in extensive crossreactions in serological tests. /this makes it difficult to distinguish between immune responses against dengue virus (DENV) and Japanese encephalitis virus (JEV), particularly in regions where these viruses co-circulate. We have demonstrated that DENV and JEV have unique epitopes on the prM. By detecting prM specific IgG, it is possible to distinguish between DENV and JEV infection. Current approach used in seroanalysis of DENV and JEV infections is based on antigens derived from the whole viral antigens.
format	Thesis
qualification_level	Master's degree
author	Wang, Seok Mui
author_facet	Wang, Seok Mui
author_sort	Wang, Seok Mui
title	Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
title_short	Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
title_full	Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
title_fullStr	Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
title_full_unstemmed	Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections
title_sort	cloning and expression of prm and it's use to distinguish host immune responses against dengue virus and japanese encephalitis virus infections
granting_institution	Universiti Malaysia Sarawak, (UNIMAS)
granting_department	Institute of Health and Community Medicine.
publishDate	2001
url	http://ir.unimas.my/id/eprint/16585/1/Wong%20Seok%20ft.pdf
_version_	1783728199316799488

Cloning and expression of prM and it's use to distinguish host immune responses against dengue virus and Japanese encephalitis virus infections

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