Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes
Inadequate coordination chemistry infonnation is available on the hydrazone and thio/carbohydrazone-organoin(IV) complexes as well as the potential biological activities they might have, five series of hydrazone and thio/carbohydrazone ligands and their organotin(IV) complexes were decided to be sy...
Saved in:
Main Author: | |
---|---|
Format: | Thesis |
Language: | English |
Published: |
2009
|
Subjects: | |
Online Access: | http://ir.unimas.my/id/eprint/28960/1/Foo%20Siong.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my-unimas-ir.28960 |
---|---|
record_format |
uketd_dc |
spelling |
my-unimas-ir.289602023-03-28T01:13:08Z Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes 2009 Foo, Siong Wan. QD Chemistry Inadequate coordination chemistry infonnation is available on the hydrazone and thio/carbohydrazone-organoin(IV) complexes as well as the potential biological activities they might have, five series of hydrazone and thio/carbohydrazone ligands and their organotin(IV) complexes were decided to be synthesized. The five ligands namely methyl pyruvate benzhydrazone [HMPB, (1 )], thiophene-2-carboxaldehyde benzhydrazone [HTCB, (2)], carbohydrazone bis(2-hydroxyacetophenone) [H3CBA, (3)], thiocarbohydrazone bis(salicylaldehyde) [H3TCB, (4)] and pyruvic acid thiosemicarbazone [H2PAT, (5)] have been synthesized via condensation reaction. Subsequently, five series of organotin(IV) complexes have been synthesized by direct reactions of RnSnCkn (R= Me, Bu, lBu, Ph; n= 1, 2), base and ligands (1-5) in dry methanol with 1: 1: 1 or 1:2: 1 mole ratio under nitrogen atmosphere. All ligands and their organotin(IV) complexes (6-28) have been characterized by elemental analyses, molar conductivity, UV-visible, FTIR, IH and I3 C NMR spectral studies. Universiti Malaysia Sarawak (UNIMAS) 2009 Thesis http://ir.unimas.my/id/eprint/28960/ http://ir.unimas.my/id/eprint/28960/1/Foo%20Siong.pdf text en validuser masters Universiti Malaysia Sarawak (UNIMAS) Faculty of Resource Science and Technology |
institution |
Universiti Malaysia Sarawak |
collection |
UNIMAS Institutional Repository |
language |
English |
topic |
QD Chemistry |
spellingShingle |
QD Chemistry Foo, Siong Wan. Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
description |
Inadequate coordination chemistry infonnation is available on the hydrazone and thio/carbohydrazone-organoin(IV) complexes as well as the potential biological activities they might have, five series of hydrazone and thio/carbohydrazone ligands and their
organotin(IV) complexes were decided to be synthesized. The five ligands namely methyl pyruvate benzhydrazone [HMPB, (1 )], thiophene-2-carboxaldehyde benzhydrazone
[HTCB, (2)], carbohydrazone bis(2-hydroxyacetophenone) [H3CBA, (3)], thiocarbohydrazone bis(salicylaldehyde) [H3TCB, (4)] and pyruvic acid thiosemicarbazone [H2PAT, (5)] have been synthesized via condensation reaction.
Subsequently, five series of organotin(IV) complexes have been synthesized by direct reactions of RnSnCkn (R= Me, Bu, lBu, Ph; n= 1, 2), base and ligands (1-5) in dry
methanol with 1: 1: 1 or 1:2: 1 mole ratio under nitrogen atmosphere. All ligands and their organotin(IV) complexes (6-28) have been characterized by elemental analyses, molar conductivity, UV-visible, FTIR, IH and I3 C NMR spectral studies. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Foo, Siong Wan. |
author_facet |
Foo, Siong Wan. |
author_sort |
Foo, Siong Wan. |
title |
Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
title_short |
Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
title_full |
Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
title_fullStr |
Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
title_full_unstemmed |
Synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (IV) complexes |
title_sort |
synthesis, characterization and biological activities of hydrazone and thio/ carbohydrazone organotin (iv) complexes |
granting_institution |
Universiti Malaysia Sarawak (UNIMAS) |
granting_department |
Faculty of Resource Science and Technology |
publishDate |
2009 |
url |
http://ir.unimas.my/id/eprint/28960/1/Foo%20Siong.pdf |
_version_ |
1783728366059257856 |