Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus
The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the j...
Saved in:
Main Author: | |
---|---|
Format: | Thesis |
Language: | English English |
Published: |
2000
|
Subjects: | |
Online Access: | http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my-upm-ir.11211 |
---|---|
record_format |
uketd_dc |
spelling |
my-upm-ir.112112024-06-12T04:48:11Z Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus 2000-08 Mohd Taib, Nor Azizah The aim of the research is to develop an effective vaccine against vibriosis. Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive production activity of brackishwater ponds and cage-cultured fish. The pathogenicity study of V alginolyticus was performed by challenging the juvenile seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell concentrations. All the isolates caused mortality to fish at a concentration as low as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by scanning and transmission electron microscopy, revealed the presence of V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In addition, the V .alginolyticus cells were observed in the spleen. These pathological changes showed that V alginolyticus was responsible for the death of the infected seabass. 2000-08 Thesis http://psasir.upm.edu.my/id/eprint/11211/ http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf text en public masters Universiti Putra Malaysia Faculty of Medicine and Health Science Shamsudin, Mariana Nor English |
institution |
Universiti Putra Malaysia |
collection |
PSAS Institutional Repository |
language |
English English |
advisor |
Shamsudin, Mariana Nor |
topic |
|
spellingShingle |
Mohd Taib, Nor Azizah Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
description |
The aim of the research is to develop an effective vaccine against vibriosis.
Vibriosis is a bacterial disease caused by Vibrio spp due to the intensive
production activity of brackishwater ponds and cage-cultured fish. The
pathogenicity study of V alginolyticus was performed by challenging the juvenile
seabass (10±0.75 g) with 5 different isolates of V alginolyticus at different cell
concentrations. All the isolates caused mortality to fish at a concentration as low
as 0.2 optical density (6.28 X 103 CFU/ml). Ultrastructure changes observed by
scanning and transmission electron microscopy, revealed the presence of
V .alginolyticus in the gills, liver, muscle, spleen and kidney of infected fish. In
addition, the V .alginolyticus cells were observed in the spleen. These
pathological changes showed that V alginolyticus was responsible for the death of
the infected seabass. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Mohd Taib, Nor Azizah |
author_facet |
Mohd Taib, Nor Azizah |
author_sort |
Mohd Taib, Nor Azizah |
title |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_short |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_full |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_fullStr |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_full_unstemmed |
Vibriosis Vaccine Development: Pathogenesis, Immunological And Molecular Characterization Of Vibrio Alginolyticus |
title_sort |
vibriosis vaccine development: pathogenesis, immunological and molecular characterization of vibrio alginolyticus |
granting_institution |
Universiti Putra Malaysia |
granting_department |
Faculty of Medicine and Health Science |
publishDate |
2000 |
url |
http://psasir.upm.edu.my/id/eprint/11211/1/FPSK_M_2001_1.pdf |
_version_ |
1804888625112940544 |