Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep
The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin exper...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English English |
| Published: |
2001
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
my-upm-ir.11224 |
|---|---|
| record_format |
uketd_dc |
| spelling |
my-upm-ir.112242024-06-12T08:34:30Z Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep 2001-02 Ab. Hamid, Hasiah The protective effect of phenobarbitone and griseofulvin against signal grass (B. decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment and twenty-seven animals were used in griseofulvin experiment. Grazing on signal grass significantly decreased the concentration of cytochrome P-4S0 and the activity of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4- hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and kidney of sheep. The concentration of cytochrome P-4S0 was determined in microsomal fraction according to the method of Omura and Sato (1964a) as described by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4- hydroxylase were determined using Mazel, 1971 method by estimating the 2001-02 Thesis http://psasir.upm.edu.my/id/eprint/11224/ http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf text en public masters Universiti Putra Malaysia Faculty of Medicine and Health Science Abdullah, Abdul Salam English |
| institution |
Universiti Putra Malaysia |
| collection |
PSAS Institutional Repository |
| language |
English English |
| advisor |
Abdullah, Abdul Salam |
| topic |
|
| spellingShingle |
Ab. Hamid, Hasiah Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| description |
The protective effect of phenobarbitone and griseofulvin against signal grass (B.
decumbens) toxicity were studied in fifty-three Wiltshire x Malin (Indigenous
Malaysian) male sheep. Twenty-six animals were used in phenobarbitone experiment
and twenty-seven animals were used in griseofulvin experiment. Grazing on signal
grass significantly decreased the concentration of cytochrome P-4S0 and the activity
of drug metabolizing enzyme, viz. aminopyrine-N-demethylase, aniline-4-
hydroxylase, UDP-glucuronyltransferase and glutathione-S-transferase in liver and
kidney of sheep. The concentration of cytochrome P-4S0 was determined in
microsomal fraction according to the method of Omura and Sato (1964a) as described
by Mazel (1971). The activities of aminopyrine-N-demethylase and aniline-4-
hydroxylase were determined using Mazel, 1971 method by estimating the |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Ab. Hamid, Hasiah |
| author_facet |
Ab. Hamid, Hasiah |
| author_sort |
Ab. Hamid, Hasiah |
| title |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_short |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_full |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_fullStr |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_full_unstemmed |
Protective Effect Of Phenorbarbitone And Griseofulvin Againt Signal Grass (Brachiaria Decumbens)Toxiciti In Sheep |
| title_sort |
protective effect of phenorbarbitone and griseofulvin againt signal grass (brachiaria decumbens)toxiciti in sheep |
| granting_institution |
Universiti Putra Malaysia |
| granting_department |
Faculty of Medicine and Health Science |
| publishDate |
2001 |
| url |
http://psasir.upm.edu.my/id/eprint/11224/1/FPSK_M_2001_11.pdf |
| _version_ |
1804888627631620096 |