Evidence Of Astrocytic Reactivity During Vestibular Compensation

Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous syst...

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Main Author: Lee, Su Ann
Format: Thesis
Language:English
English
Published: 2003
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Online Access:http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf
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spelling my-upm-ir.112472024-06-13T01:43:11Z Evidence Of Astrocytic Reactivity During Vestibular Compensation 2003-07 Lee, Su Ann Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous system. The present study was conducted to investigate the behavioural changes of mice and the morphological changes and distribution of astrocytes following unilateral labyrinthectomy. Thirty-five mice (Mus musculus) underwent unilateral labyrinthectomy (UL) and fourteen underwent sham-operation. Their behavioural changes following surgical removal of labyrinths, or sham-operation, were observed. The UL groups displayed behavioural changes including head tilt, circular walking, barrel-rolling and extension and flexion of limbs. These behavioural symptoms disappeared within approximately 3 hours. For the sham-operated animals, these symptoms were absent. 2003-07 Thesis http://psasir.upm.edu.my/id/eprint/11247/ http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf text en public masters Universiti Putra Malaysia Faculty of Medicine and Health Science Sulaiman, Mohd Roslan English
institution Universiti Putra Malaysia
collection PSAS Institutional Repository
language English
English
advisor Sulaiman, Mohd Roslan
topic


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Lee, Su Ann
Evidence Of Astrocytic Reactivity During Vestibular Compensation
description Vestibular compensation is the spontaneous disappearance of postural and oculomotor imbalance exhibited by the vestibular system in response to decreased inputs from the labyrinths. Astrocytes in the vestibular nuclei have been reported to have a role in the plasticity of the central nervous system. The present study was conducted to investigate the behavioural changes of mice and the morphological changes and distribution of astrocytes following unilateral labyrinthectomy. Thirty-five mice (Mus musculus) underwent unilateral labyrinthectomy (UL) and fourteen underwent sham-operation. Their behavioural changes following surgical removal of labyrinths, or sham-operation, were observed. The UL groups displayed behavioural changes including head tilt, circular walking, barrel-rolling and extension and flexion of limbs. These behavioural symptoms disappeared within approximately 3 hours. For the sham-operated animals, these symptoms were absent.
format Thesis
qualification_level Master's degree
author Lee, Su Ann
author_facet Lee, Su Ann
author_sort Lee, Su Ann
title Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_short Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_full Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_fullStr Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_full_unstemmed Evidence Of Astrocytic Reactivity During Vestibular Compensation
title_sort evidence of astrocytic reactivity during vestibular compensation
granting_institution Universiti Putra Malaysia
granting_department Faculty of Medicine and Health Science
publishDate 2003
url http://psasir.upm.edu.my/id/eprint/11247/1/FPSK_M_2003_5.pdf
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