Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties

Ziziphus mauritiana L. derived from Rhamnaceae family plant (known as Bidara tree in Malaysia) has been consumed by Malaysian through processing the fruit into pickles or eating it fresh, while the leaves are frequently used in traditional medicine, particularly in Islamic medicine. Although the...

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Main Author:	Zahari, Nur Syuhada
Format:	Thesis
Language:	English
Published:	2021
Subjects:	Indian jujube Fiber in human nutrition Hypoglycemic agents
Online Access:	http://psasir.upm.edu.my/id/eprint/113816/1/113816.pdf
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id	my-upm-ir.113816
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spelling	my-upm-ir.1138162024-11-27T04:00:02Z Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties 2021-06 Zahari, Nur Syuhada Ziziphus mauritiana L. derived from Rhamnaceae family plant (known as Bidara tree in Malaysia) has been consumed by Malaysian through processing the fruit into pickles or eating it fresh, while the leaves are frequently used in traditional medicine, particularly in Islamic medicine. Although the Z. mauritiana L. plant rich in macronutrients, micronutrients, and phytochemicals that offer health benefits, yet, it is still considered underutilized in Malaysia due to a lack of scientific information about the health promoting effect of its fiber. In other countries, Z. mauritiana L. also used widely as traditional medicine and recently researchers start to study scientifically the health benefits of this plant especially in Asian country. The purpose of the study was therefore to explore the physicochemical properties relevant to the nutritional quality of one of the sources of dietary fiber (mucilage) necessary for the maintenance of population health in the community, especially in treating diabetes mellitus. Additionally, the potent phenolic content and α-amylase and α-glucosidase enzyme inhibitory activity were also investigated. The extraction yield of mucilage was investigated from Z. mauritiana L. fruit pulp and leaves where the preliminary screening has shown that the higher mucilage yield was obtained from the leaves with 1.24%, while the mucilage from the pulp yielded 0.34%. The mucilage of Z. mauritiana L. leaves with good hydration properties of swelling capacity (6.87 ± 0.23 mL/g), water holding capacity (3.960 ± 0.200 g/g), oil holding capacity (0.507 ± 0.083 g/g), and its emulsifying properties including emulsifying activity (56.0 ± 4.00%) and emulsifying stability (70.87 ± 2.31%) indicate that it may have the capability in regulating postprandial hyperglycemia. Fourier transform infrared spectroscopy (FTIR) demonstrated the band of functional group characteristics of dietary fiber while scanning electron microscopy (SEM) analysis revealed the structural characteristic of the extracted Z. mauritiana L. mucilage. Glucose dialysis retardation index (GDRI) analysis on Z. mauritiana L. leaves dietary fiber showed decreasing effect overtime at minutes 60 (from 70.94 to 62.57%). The phytochemical analysis has shown that the total phenolic content of the fiber extract was 6.13 mg GAE/g dry sample extract while the total flavonoid content was 83.00 mg QE/g dry sample extract. In vitro studies exhibit excellent α- amylase and α-glucosidase inhibition activity with an IC50 of 138.3 μg/mL and 11.04 μg/mL, respectively as compared to one of synthetic drugs used for treating diabetes, acarbose. These features make the crude Z. mauritiana L. mucilaginous extract a remarkable candidate for functional food and nutraceutical dietary fiber especially in associated with antidiabetes Indian jujube Fiber in human nutrition Hypoglycemic agents 2021-06 Thesis http://psasir.upm.edu.my/id/eprint/113816/ http://psasir.upm.edu.my/id/eprint/113816/1/113816.pdf text en public masters Universiti Putra Malaysia Indian jujube Fiber in human nutrition Hypoglycemic agents Zaidan, Uswatun Hasanah
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
advisor	Zaidan, Uswatun Hasanah
topic	Indian jujube Fiber in human nutrition Hypoglycemic agents
spellingShingle	Indian jujube Fiber in human nutrition Hypoglycemic agents Zahari, Nur Syuhada Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
description	Ziziphus mauritiana L. derived from Rhamnaceae family plant (known as Bidara tree in Malaysia) has been consumed by Malaysian through processing the fruit into pickles or eating it fresh, while the leaves are frequently used in traditional medicine, particularly in Islamic medicine. Although the Z. mauritiana L. plant rich in macronutrients, micronutrients, and phytochemicals that offer health benefits, yet, it is still considered underutilized in Malaysia due to a lack of scientific information about the health promoting effect of its fiber. In other countries, Z. mauritiana L. also used widely as traditional medicine and recently researchers start to study scientifically the health benefits of this plant especially in Asian country. The purpose of the study was therefore to explore the physicochemical properties relevant to the nutritional quality of one of the sources of dietary fiber (mucilage) necessary for the maintenance of population health in the community, especially in treating diabetes mellitus. Additionally, the potent phenolic content and α-amylase and α-glucosidase enzyme inhibitory activity were also investigated. The extraction yield of mucilage was investigated from Z. mauritiana L. fruit pulp and leaves where the preliminary screening has shown that the higher mucilage yield was obtained from the leaves with 1.24%, while the mucilage from the pulp yielded 0.34%. The mucilage of Z. mauritiana L. leaves with good hydration properties of swelling capacity (6.87 ± 0.23 mL/g), water holding capacity (3.960 ± 0.200 g/g), oil holding capacity (0.507 ± 0.083 g/g), and its emulsifying properties including emulsifying activity (56.0 ± 4.00%) and emulsifying stability (70.87 ± 2.31%) indicate that it may have the capability in regulating postprandial hyperglycemia. Fourier transform infrared spectroscopy (FTIR) demonstrated the band of functional group characteristics of dietary fiber while scanning electron microscopy (SEM) analysis revealed the structural characteristic of the extracted Z. mauritiana L. mucilage. Glucose dialysis retardation index (GDRI) analysis on Z. mauritiana L. leaves dietary fiber showed decreasing effect overtime at minutes 60 (from 70.94 to 62.57%). The phytochemical analysis has shown that the total phenolic content of the fiber extract was 6.13 mg GAE/g dry sample extract while the total flavonoid content was 83.00 mg QE/g dry sample extract. In vitro studies exhibit excellent α- amylase and α-glucosidase inhibition activity with an IC50 of 138.3 μg/mL and 11.04 μg/mL, respectively as compared to one of synthetic drugs used for treating diabetes, acarbose. These features make the crude Z. mauritiana L. mucilaginous extract a remarkable candidate for functional food and nutraceutical dietary fiber especially in associated with antidiabetes
format	Thesis
qualification_level	Master's degree
author	Zahari, Nur Syuhada
author_facet	Zahari, Nur Syuhada
author_sort	Zahari, Nur Syuhada
title	Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
title_short	Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
title_full	Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
title_fullStr	Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
title_full_unstemmed	Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties
title_sort	biofunctional characteristics of dietary fiber extracted from malaysian ziziphus mauritiana l. leaves and its association in vitro antidiabetics properties
granting_institution	Universiti Putra Malaysia
publishDate	2021
url	http://psasir.upm.edu.my/id/eprint/113816/1/113816.pdf
_version_	1818586165785133056

Biofunctional characteristics of dietary fiber extracted from Malaysian Ziziphus mauritiana L. leaves and its association in vitro antidiabetics properties

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