Identification of Protein Kinase Inhibitory Activities Fromstreptomyces Strain H7372 for Potential Use As Anti-Canceragent
Aberrations in the phospbatidylinositol3-kinase (PI3K)IAkt pathway have been found in a wide spectrum of human cancers. Activation of Akt and inactivation of the downstream substrates such as GSK-3P, BAD and Forkhead family (FKHR) proteins are relevant to promote cell survival, proliferation and...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2007
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/6438/1/FPSK%28M%29_2007_18.pdf |
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