Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection

Polypyrrole-Tannin (PPy/TA) nanocomposite was prepared in the presence of cationic surfactant, cetyltrimethylammonium bromide (CTAB) using the chemical polymerization method. The resulting PPy/TA/CTAB nanocomposite was used to modify screen printed carbon electrode (SPCE) for developing a dopamin...

Full description

Saved in:

Bibliographic Details
Main Author:	Mohd Azli, Nor Farhana Waheeda
Format:	Thesis
Language:	English
Published:	2018
Subjects:	Polymerization Nanocomposites (Materials) Dopamine
Online Access:	http://psasir.upm.edu.my/id/eprint/83650/1/FS%202019%2015%20-%20ir.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-upm-ir.83650
record_format	uketd_dc
spelling	my-upm-ir.836502022-01-05T04:40:43Z Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection 2018-11 Mohd Azli, Nor Farhana Waheeda Polypyrrole-Tannin (PPy/TA) nanocomposite was prepared in the presence of cationic surfactant, cetyltrimethylammonium bromide (CTAB) using the chemical polymerization method. The resulting PPy/TA/CTAB nanocomposite was used to modify screen printed carbon electrode (SPCE) for developing a dopamine (DA) biosensor. The presence of TA was able to repel the interference molecules (AA and UA) in DA detection, while CTAB act as a soft-template in tailoring the nanostructure of PPy. The electrochemical properties of the modified electrode were studied via cyclic voltammetry (CV) and SPCE/PPy/TA/CTAB-modified electrode revealed a higher current response compared to modified electrode of SPCE/PPy and SPCE/PPy/TA. The results obtained from Electrochemical Impedance Spectroscopy (EIS) exhibited a lower value of charge transfer resistance (Rct) for the SPCE/PPy/TA/CTAB-modified electrode indicating an enhancement in the electron transfer rate. The Fourier-Transform Infrared (FTIR) spectra of nanocomposite displayed the typical characteristic peaks of TA and CTAB which are evidences of the incorporation of these components into PPy. Electron Microscopy (TEM) revealed a rod-like structure with a lumpy surface for PPy/TA/CTAB nanocomposite, justifying the highest current response for the modified electrode. Brunauer-Emmet-Teller (BET) measurement displayed a surface area of 23.5 m2/g for PPy/TA/CTAB nanocomposite. Response Surface Methodology (RSM) has been applied to optimize the selected parameters and conditions in order to maximize the biosensor’s performance and its sensitivity. Amperometry and Differential Pulse Voltammetry (DPV) analysis were employed for all electrochemical measurements and dopamine detection in two different ranges of 0.1–2 μM and 2–50 μM. The good adhesion of nanocomposite on the electrode surface, as well as the high surface area and porosity of the modified electrode, enhanced the diffusion of DA molecules inside the matrix. Amperometry analysis of the SPCE/PPy/TA/CTAB modified electrode displayed a good sensitivity of 0.039 μA (μM)−1 towards dopamine with the limit of detection (LOD) of 2.9×10−7 M. The modified biosensor also excludes the interfering species of ascorbic acid (AA) and uric acid (UA) which makes the sensor suitable for DA determination. This biosensor showed an acceptable reproducibility and repeatability with low relative standard deviations (RSD) of 4.8% and 4.4%, respectively. The current response remained about 81.5% of the original value after 21 days indicating an accepted stability over time. Polymerization Nanocomposites (Materials) Dopamine 2018-11 Thesis http://psasir.upm.edu.my/id/eprint/83650/ http://psasir.upm.edu.my/id/eprint/83650/1/FS%202019%2015%20-%20ir.pdf text en public masters Universiti Putra Malaysia Polymerization Nanocomposites (Materials) Dopamine M. Abdi, Mahnaz
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
advisor	M. Abdi, Mahnaz
topic	Polymerization Nanocomposites (Materials) Dopamine
spellingShingle	Polymerization Nanocomposites (Materials) Dopamine Mohd Azli, Nor Farhana Waheeda Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
description	Polypyrrole-Tannin (PPy/TA) nanocomposite was prepared in the presence of cationic surfactant, cetyltrimethylammonium bromide (CTAB) using the chemical polymerization method. The resulting PPy/TA/CTAB nanocomposite was used to modify screen printed carbon electrode (SPCE) for developing a dopamine (DA) biosensor. The presence of TA was able to repel the interference molecules (AA and UA) in DA detection, while CTAB act as a soft-template in tailoring the nanostructure of PPy. The electrochemical properties of the modified electrode were studied via cyclic voltammetry (CV) and SPCE/PPy/TA/CTAB-modified electrode revealed a higher current response compared to modified electrode of SPCE/PPy and SPCE/PPy/TA. The results obtained from Electrochemical Impedance Spectroscopy (EIS) exhibited a lower value of charge transfer resistance (Rct) for the SPCE/PPy/TA/CTAB-modified electrode indicating an enhancement in the electron transfer rate. The Fourier-Transform Infrared (FTIR) spectra of nanocomposite displayed the typical characteristic peaks of TA and CTAB which are evidences of the incorporation of these components into PPy. Electron Microscopy (TEM) revealed a rod-like structure with a lumpy surface for PPy/TA/CTAB nanocomposite, justifying the highest current response for the modified electrode. Brunauer-Emmet-Teller (BET) measurement displayed a surface area of 23.5 m2/g for PPy/TA/CTAB nanocomposite. Response Surface Methodology (RSM) has been applied to optimize the selected parameters and conditions in order to maximize the biosensor’s performance and its sensitivity. Amperometry and Differential Pulse Voltammetry (DPV) analysis were employed for all electrochemical measurements and dopamine detection in two different ranges of 0.1–2 μM and 2–50 μM. The good adhesion of nanocomposite on the electrode surface, as well as the high surface area and porosity of the modified electrode, enhanced the diffusion of DA molecules inside the matrix. Amperometry analysis of the SPCE/PPy/TA/CTAB modified electrode displayed a good sensitivity of 0.039 μA (μM)−1 towards dopamine with the limit of detection (LOD) of 2.9×10−7 M. The modified biosensor also excludes the interfering species of ascorbic acid (AA) and uric acid (UA) which makes the sensor suitable for DA determination. This biosensor showed an acceptable reproducibility and repeatability with low relative standard deviations (RSD) of 4.8% and 4.4%, respectively. The current response remained about 81.5% of the original value after 21 days indicating an accepted stability over time.
format	Thesis
qualification_level	Master's degree
author	Mohd Azli, Nor Farhana Waheeda
author_facet	Mohd Azli, Nor Farhana Waheeda
author_sort	Mohd Azli, Nor Farhana Waheeda
title	Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
title_short	Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
title_full	Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
title_fullStr	Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
title_full_unstemmed	Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
title_sort	synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection
granting_institution	Universiti Putra Malaysia
publishDate	2018
url	http://psasir.upm.edu.my/id/eprint/83650/1/FS%202019%2015%20-%20ir.pdf
_version_	1747813405598679040

Synthesis of polypyrrole/tannin/cetyltrimethylammonium bromide nanocomposites for dopamine detection

Similar Items