Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women

The role of dietary glycemic index (GI) and glycemic load (GL) intake in GDM incidence is uncertain. This prospective cohort study was conducted to determine the contribution of calculated dietary GI and GL towards the incidence of GDM among healthy pregnant women in Seremban district. Pregnan...

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Main Author:	Hasbullah, Farah Yasmin
Format:	Thesis
Language:	English
Published:	2016
Subjects:	Glycemic Index Diabetes Mellitus Dietary Carbohydrates
Online Access:	http://psasir.upm.edu.my/id/eprint/85551/1/FPSK%28M%29%202016%2083%20ir.pdf
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spelling	my-upm-ir.855512021-12-14T02:02:37Z Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women 2016-04 Hasbullah, Farah Yasmin The role of dietary glycemic index (GI) and glycemic load (GL) intake in GDM incidence is uncertain. This prospective cohort study was conducted to determine the contribution of calculated dietary GI and GL towards the incidence of GDM among healthy pregnant women in Seremban district. Pregnant women were recruited in the first trimester and were followed-up until their second trimester. GDM was diagnosed during the second trimester of pregnancy using International Diabetes in Pregnancy Study Groups (IADPSG) criteria. Primary outcome was GDM incidence whereas calculated dietary GI and GL were the primary independent variables. Dietary intake and selected established risk factors including maternal age, ethnicity, family history of diabetes mellitus (DM), history of GDM, and pre-pregnancy body mass index (BMI) acted as covariates to dietary GI and GL. These risk factors were obtained through interviews or medical records. Food intake, dietary GI and GI were assessed using food frequency questionnaire (FFQ). Independent t-test was used to compare the differences between GDM and non-GDM respondents. Binary logistic regression was used to determine the contribution of calculated dietary GI and GL towards GDM incidence. The number of respondents recruited was 347, with a response rate of 78.9%. Data analysis was performed for respondents who completed the assessments during the second trimester (n = 294). In this cohort, the incidence of GDM was 11.6%. GDM respondents tended to have a history of GDM and be overweight or obese. GDM respondents had significantly lower carbohydrate, dietary GI and GL intakes during the first trimester. Dietary GI and GL intake during the first trimester significantly predicted GDM incidence in a crude odds ratio. After adjusting for confounders, only dietary GI intake during the first trimester was a significant contributor towards GDM incidence; however, the association was negative (β = -0.186, OR 0.830, p = 0.035). The negative relationship could possibly be due to dietary misreporting or the invalidity of the method used in assessing dietary GI intake. Dietary GL was positively associated with GDM incidence during both trimesters, but the association was not significant. In conclusion, dietary GI significantly contributed towards GDM incidence, in addition to other established risk factors including pre-pregnancy BMI and history of GDM. However, failing to demonstrate positive links between dietary GI intake and GDM incidence was unexpected which warrants future investigation. Glycemic Index Diabetes Mellitus Dietary Carbohydrates 2016-04 Thesis http://psasir.upm.edu.my/id/eprint/85551/ http://psasir.upm.edu.my/id/eprint/85551/1/FPSK%28M%29%202016%2083%20ir.pdf text en public masters Universiti Putra Malaysia Glycemic Index Diabetes Mellitus Dietary Carbohydrates Mohd. Yusof, Barakatun Nisak
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
advisor	Mohd. Yusof, Barakatun Nisak
topic	Glycemic Index Diabetes Mellitus Dietary Carbohydrates
spellingShingle	Glycemic Index Diabetes Mellitus Dietary Carbohydrates Hasbullah, Farah Yasmin Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
description	The role of dietary glycemic index (GI) and glycemic load (GL) intake in GDM incidence is uncertain. This prospective cohort study was conducted to determine the contribution of calculated dietary GI and GL towards the incidence of GDM among healthy pregnant women in Seremban district. Pregnant women were recruited in the first trimester and were followed-up until their second trimester. GDM was diagnosed during the second trimester of pregnancy using International Diabetes in Pregnancy Study Groups (IADPSG) criteria. Primary outcome was GDM incidence whereas calculated dietary GI and GL were the primary independent variables. Dietary intake and selected established risk factors including maternal age, ethnicity, family history of diabetes mellitus (DM), history of GDM, and pre-pregnancy body mass index (BMI) acted as covariates to dietary GI and GL. These risk factors were obtained through interviews or medical records. Food intake, dietary GI and GI were assessed using food frequency questionnaire (FFQ). Independent t-test was used to compare the differences between GDM and non-GDM respondents. Binary logistic regression was used to determine the contribution of calculated dietary GI and GL towards GDM incidence. The number of respondents recruited was 347, with a response rate of 78.9%. Data analysis was performed for respondents who completed the assessments during the second trimester (n = 294). In this cohort, the incidence of GDM was 11.6%. GDM respondents tended to have a history of GDM and be overweight or obese. GDM respondents had significantly lower carbohydrate, dietary GI and GL intakes during the first trimester. Dietary GI and GL intake during the first trimester significantly predicted GDM incidence in a crude odds ratio. After adjusting for confounders, only dietary GI intake during the first trimester was a significant contributor towards GDM incidence; however, the association was negative (β = -0.186, OR 0.830, p = 0.035). The negative relationship could possibly be due to dietary misreporting or the invalidity of the method used in assessing dietary GI intake. Dietary GL was positively associated with GDM incidence during both trimesters, but the association was not significant. In conclusion, dietary GI significantly contributed towards GDM incidence, in addition to other established risk factors including pre-pregnancy BMI and history of GDM. However, failing to demonstrate positive links between dietary GI intake and GDM incidence was unexpected which warrants future investigation.
format	Thesis
qualification_level	Master's degree
author	Hasbullah, Farah Yasmin
author_facet	Hasbullah, Farah Yasmin
author_sort	Hasbullah, Farah Yasmin
title	Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
title_short	Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
title_full	Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
title_fullStr	Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
title_full_unstemmed	Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
title_sort	calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women
granting_institution	Universiti Putra Malaysia
publishDate	2016
url	http://psasir.upm.edu.my/id/eprint/85551/1/FPSK%28M%29%202016%2083%20ir.pdf
_version_	1747813558785146880

Calculated dietary glycemic index, glycemic load and incidence of gestational diabetes mellitus in healthy pregnant women

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