Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)

Drug discovery has been a goal of mankind since prehistoric times. Plants continue to be an exceptionally viable source of biologically active natural products. However, only small portion of the higher plants has been phytochemically and pharmacologically investigated. Two separate collections...

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Main Author:	Susidarti, Ratna Asmah
Format:	Thesis
Language:	English English
Published:	2003
Subjects:	Rutaceae. Myrtaceae.
Online Access:	http://psasir.upm.edu.my/id/eprint/9560/1/FSAS_2003_20_A.pdf
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id	my-upm-ir.9560
record_format	uketd_dc
spelling	my-upm-ir.95602012-08-27T07:53:36Z Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae) 2003-03 Susidarti, Ratna Asmah Drug discovery has been a goal of mankind since prehistoric times. Plants continue to be an exceptionally viable source of biologically active natural products. However, only small portion of the higher plants has been phytochemically and pharmacologically investigated. Two separate collections of Micromelum minutum from Sabah and two Eugenia species, E. chlorantha and E. cumingiana collected from the northern forest of Perak were subjected to phytochemical investigation with the isolation of a number of compounds. The structures of these compounds were elucidated by using spectroscopic methods such as IR, UV, NMR, MS and also by comparison with previous reports. The crude extracts, essential oil and isolated compounds from these plant materials were evaluated for their antiinflammatory, cytotoxic and antimicrobial activities using carrageenan-induced rat paw oedema, MTT and disc diffusion methods, respectively. Some isolated compounds showed interesting biological activities. Rutaceae. Myrtaceae. 2003-03 Thesis http://psasir.upm.edu.my/id/eprint/9560/ http://psasir.upm.edu.my/id/eprint/9560/1/FSAS_2003_20_A.pdf application/pdf en public phd doctoral Universiti Putra Malaysia Rutaceae. Myrtaceae. Faculty of Science and Environmental Studies English
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English English
topic	Rutaceae. Myrtaceae.
spellingShingle	Rutaceae. Myrtaceae. Susidarti, Ratna Asmah Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
description	Drug discovery has been a goal of mankind since prehistoric times. Plants continue to be an exceptionally viable source of biologically active natural products. However, only small portion of the higher plants has been phytochemically and pharmacologically investigated. Two separate collections of Micromelum minutum from Sabah and two Eugenia species, E. chlorantha and E. cumingiana collected from the northern forest of Perak were subjected to phytochemical investigation with the isolation of a number of compounds. The structures of these compounds were elucidated by using spectroscopic methods such as IR, UV, NMR, MS and also by comparison with previous reports. The crude extracts, essential oil and isolated compounds from these plant materials were evaluated for their antiinflammatory, cytotoxic and antimicrobial activities using carrageenan-induced rat paw oedema, MTT and disc diffusion methods, respectively. Some isolated compounds showed interesting biological activities.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Susidarti, Ratna Asmah
author_facet	Susidarti, Ratna Asmah
author_sort	Susidarti, Ratna Asmah
title	Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
title_short	Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
title_full	Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
title_fullStr	Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
title_full_unstemmed	Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)
title_sort	chemical constituents and biological activities of micromelum minutum (rutaceae) and two eugenia species (myrtaceae)
granting_institution	Universiti Putra Malaysia
granting_department	Faculty of Science and Environmental Studies
publishDate	2003
url	http://psasir.upm.edu.my/id/eprint/9560/1/FSAS_2003_20_A.pdf
_version_	1747810981036163072

Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)

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