The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study
Porcine based blood thinners namely low molecular heparin (LMWH) drugs are known to be highly potential to prevent the life-threatening event cause by blood clotting or Venous Thromboembolism (VTE). However, its usage was clearly prohibited according to The Muzakarah (discussion) Committee of the Na...
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Universiti Sains Islam Malaysia |
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Blood thinners Molecular heparin (LMWH) Pork -- Detection Swine--Physiology. Pregnant women--Health. |
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Blood thinners Molecular heparin (LMWH) Pork -- Detection Swine--Physiology. Pregnant women--Health. Zizi Azlinda Binti Mohd Yusof The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| description |
Porcine based blood thinners namely low molecular heparin (LMWH) drugs are known to be highly potential to prevent the life-threatening event cause by blood clotting or Venous Thromboembolism (VTE). However, its usage was clearly prohibited according to The Muzakarah (discussion) Committee of the National Council for Islamic Religious Affairs of Malaysia (MCMKI) / JAKIM National Council decision in 2009. Yet, LMWH usage is considered permissible for treatment purposes for critically ill patients in the life-threatening stage/darurah stage. The halal alternative of LMWH, Fondaparinux is recommended to replace LMWH even though the animal derivative-free blood thinner drug has an inadequate / unstable safety profile for pregnant and postpartum women. The MCMKI’s decision to allow exemption of LMWH usage in emergency condition (sighah) creates confusion when prescribed to pregnant and postpartum women. Thus, it has made LMWH a less favorable choice due to the dilemma between its usage and the exceptions in the MCMKI’s statement. This study used qualitative methodology through document analysis techniques and interviews. Twenty-one expertise consisting of ten medical consultants from three departments, namely seven obstetricians and gynaecologists (O&G), a cardiovascular specialist, a hematologist and a family physician. On the other hand, three senior pharmacists and eight shariah experts among muftis and academicians from the public universities were interviewed for this study. The findings of the study revealed that pregnant women undergone physiological changes in which their blood easily clots, and some easily develop massive clotting event (Venous Thromboembolism or VTE) and can be fatal. LMWH is the best preventative medicine for VTE condition, and it should be used during pregnancy and postpartum for those who at risk. Thus, based on the justification of fiqhiyyah methods such as Al-Darar Yuzal and Al-Hajah Tunazzal Manzilah Al-Darurah, the usage of LMWH is permissible from fiqh perspective upon pregnant and postpartum mothers who are indicated. |
| format |
Thesis |
| author |
Zizi Azlinda Binti Mohd Yusof |
| author_facet |
Zizi Azlinda Binti Mohd Yusof |
| author_sort |
Zizi Azlinda Binti Mohd Yusof |
| title |
The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| title_short |
The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| title_full |
The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| title_fullStr |
The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| title_full_unstemmed |
The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study |
| title_sort |
usage of porcine base anticoagulant during pregnancy and puerperium from fiqh perspective: low molecular weight heparin (lmwh) as a case study |
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Universiti Sains Islam Malaysia |
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my-usim-ddms-132832024-05-29T18:26:15Z The Usage Of Porcine Base Anticoagulant During Pregnancy And Puerperium From Fiqh Perspective: Low Molecular Weight Heparin (LMWH) As A Case Study Zizi Azlinda Binti Mohd Yusof Porcine based blood thinners namely low molecular heparin (LMWH) drugs are known to be highly potential to prevent the life-threatening event cause by blood clotting or Venous Thromboembolism (VTE). However, its usage was clearly prohibited according to The Muzakarah (discussion) Committee of the National Council for Islamic Religious Affairs of Malaysia (MCMKI) / JAKIM National Council decision in 2009. Yet, LMWH usage is considered permissible for treatment purposes for critically ill patients in the life-threatening stage/darurah stage. The halal alternative of LMWH, Fondaparinux is recommended to replace LMWH even though the animal derivative-free blood thinner drug has an inadequate / unstable safety profile for pregnant and postpartum women. The MCMKI’s decision to allow exemption of LMWH usage in emergency condition (sighah) creates confusion when prescribed to pregnant and postpartum women. Thus, it has made LMWH a less favorable choice due to the dilemma between its usage and the exceptions in the MCMKI’s statement. This study used qualitative methodology through document analysis techniques and interviews. Twenty-one expertise consisting of ten medical consultants from three departments, namely seven obstetricians and gynaecologists (O&G), a cardiovascular specialist, a hematologist and a family physician. On the other hand, three senior pharmacists and eight shariah experts among muftis and academicians from the public universities were interviewed for this study. The findings of the study revealed that pregnant women undergone physiological changes in which their blood easily clots, and some easily develop massive clotting event (Venous Thromboembolism or VTE) and can be fatal. LMWH is the best preventative medicine for VTE condition, and it should be used during pregnancy and postpartum for those who at risk. Thus, based on the justification of fiqhiyyah methods such as Al-Darar Yuzal and Al-Hajah Tunazzal Manzilah Al-Darurah, the usage of LMWH is permissible from fiqh perspective upon pregnant and postpartum mothers who are indicated. Universiti Sains Islam Malaysia 2021-02 Thesis en_US https://oarep.usim.edu.my/handle/123456789/13283 https://oarep.usim.edu.my/bitstreams/4e880aec-ace8-42c9-bc0e-98e6cf8fd828/download 8a4605be74aa9ea9d79846c1fba20a33 https://oarep.usim.edu.my/bitstreams/79273ec2-dd1b-4382-a660-408b845e091d/download ef420e4cf69d40588c726a20de45fe2e https://oarep.usim.edu.my/bitstreams/108aaca9-a92a-43dd-8f13-20974337be18/download dc7f12257a71786fd026d9370f9e8e19 https://oarep.usim.edu.my/bitstreams/76d873c8-985d-42f5-8433-43a935adb299/download 04a984b655345513759ca71ffa7085bc https://oarep.usim.edu.my/bitstreams/9d50bc42-54d5-496f-a1e9-08e06ef1a1eb/download 5f5f23beb8e6efed79ba89ff12836e0c https://oarep.usim.edu.my/bitstreams/9be677b0-750b-465e-9e08-9895b044d15f/download 03321f4f99bd1c3f4ae99fdf2eed9536 https://oarep.usim.edu.my/bitstreams/c0ff7d8e-518e-4151-bee0-53444c926cb5/download 5f3998c2db635d4a666a0e2a0f96b9dd https://oarep.usim.edu.my/bitstreams/057727fb-86f1-404f-a001-379d247dafa8/download c196fc58f9b07e03dfdb51ab709d592a https://oarep.usim.edu.my/bitstreams/a9ae7993-e8bb-4d37-b12f-25bb107efc8f/download 44642fa086ea7204b0d62e9ee2cd96ba https://oarep.usim.edu.my/bitstreams/5b9f4686-20a1-4ea7-9225-613770a21316/download 7353c7e434e92f3afe307389eed6206b https://oarep.usim.edu.my/bitstreams/eed867d1-8b7f-44c9-8e26-eadc817dbf8b/download 224683385875f6747beaf84392eddff7 https://oarep.usim.edu.my/bitstreams/ee25d87b-f4a2-47cd-88a3-4527784fb45c/download 68b329da9893e34099c7d8ad5cb9c940 https://oarep.usim.edu.my/bitstreams/ad66172e-612e-473e-9a81-dac637c48fd9/download 9e5b0cfabb029e0bf26b60b6eea1628e https://oarep.usim.edu.my/bitstreams/f2e037f2-04ab-41c9-b927-c9f57cbf76e0/download 668fa3344698a4c5fdf9eeeeb48fdc39 https://oarep.usim.edu.my/bitstreams/d396e7f3-c3fc-4cd5-8dc3-0c1606985c1b/download 3f965d06a7a464f06eb5d82559337880 https://oarep.usim.edu.my/bitstreams/a2dacc25-0ae6-442e-ad80-9600c5b12b98/download 35f1269cef4b2952f9d07ce071c999de https://oarep.usim.edu.my/bitstreams/4f54c57a-ddc9-497c-9d6d-89e7dd6997ed/download 79c9c1c30fdace276a9cc67ca0260488 https://oarep.usim.edu.my/bitstreams/628517d9-bf1a-4e88-917e-3382fbe9b18c/download 3c8e1d7d2d1b84fc60e8555da7e8ad89 https://oarep.usim.edu.my/bitstreams/26763366-aaee-4766-8df3-3ffed840f72c/download f1f72731d376aab3f219d467a20892ce https://oarep.usim.edu.my/bitstreams/837edf88-729c-4608-abd1-7afcec5726d2/download 8ee1cf6699e5ead4c3ff5553ae0e706a https://oarep.usim.edu.my/bitstreams/b30a1060-2c8c-438e-89c6-93673bcc7ba8/download e2a31f3f08d45ad48664cb8a5065aab4 Blood thinners Molecular heparin (LMWH) Pork -- Detection Swine--Physiology. Pregnant women--Health. |