α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan

Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada vaskular ginjal untuk mengawal tekanan darah. Hypertension is a ma...

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Main Author: Yen, Pei Pei
Format: Thesis
Language:English
Published: 2016
Subjects:
Online Access:http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf
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spelling my-usm-ep.326692019-04-12T05:25:21Z α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan 2016-05 Yen, Pei Pei RS1-441 Pharmacy and materia medica Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada vaskular ginjal untuk mengawal tekanan darah. Hypertension is a major cause of morbidity and mortality from renal impairment. An increase of sodium intake contributes to the pathogenesis of hypertension. α1-adrenoceptors modulate renal vascular tone in the regulation of blood pressure. This study was undertaken to investigate the effects of tempol and losartan on renal function and haemodynamics in Sprague Dawley (SD) rats fed with normal diet, SD rats fed with high sodium diet, DOCA-salt treated rats fed with normal diet and DOCA-salt treated rats fed with high sodium diet. 2016-05 Thesis http://eprints.usm.my/32669/ http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Yen, Pei Pei
α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
description Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada vaskular ginjal untuk mengawal tekanan darah. Hypertension is a major cause of morbidity and mortality from renal impairment. An increase of sodium intake contributes to the pathogenesis of hypertension. α1-adrenoceptors modulate renal vascular tone in the regulation of blood pressure. This study was undertaken to investigate the effects of tempol and losartan on renal function and haemodynamics in Sprague Dawley (SD) rats fed with normal diet, SD rats fed with high sodium diet, DOCA-salt treated rats fed with normal diet and DOCA-salt treated rats fed with high sodium diet.
format Thesis
qualification_level Master's degree
author Yen, Pei Pei
author_facet Yen, Pei Pei
author_sort Yen, Pei Pei
title α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
title_short α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
title_full α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
title_fullStr α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
title_full_unstemmed α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
title_sort α1-adrenoceptors and at1 receptors in the modulation of renal hemodynamics in high salt and doca models of hypertensive rats treated with tempol and losartan
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2016
url http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf
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