α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan
Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada vaskular ginjal untuk mengawal tekanan darah. Hypertension is a ma...
Saved in:
Main Author: | |
---|---|
Format: | Thesis |
Language: | English |
Published: |
2016
|
Subjects: | |
Online Access: | http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my-usm-ep.32669 |
---|---|
record_format |
uketd_dc |
spelling |
my-usm-ep.326692019-04-12T05:25:21Z α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan 2016-05 Yen, Pei Pei RS1-441 Pharmacy and materia medica Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada vaskular ginjal untuk mengawal tekanan darah. Hypertension is a major cause of morbidity and mortality from renal impairment. An increase of sodium intake contributes to the pathogenesis of hypertension. α1-adrenoceptors modulate renal vascular tone in the regulation of blood pressure. This study was undertaken to investigate the effects of tempol and losartan on renal function and haemodynamics in Sprague Dawley (SD) rats fed with normal diet, SD rats fed with high sodium diet, DOCA-salt treated rats fed with normal diet and DOCA-salt treated rats fed with high sodium diet. 2016-05 Thesis http://eprints.usm.my/32669/ http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi |
institution |
Universiti Sains Malaysia |
collection |
USM Institutional Repository |
language |
English |
topic |
RS1-441 Pharmacy and materia medica |
spellingShingle |
RS1-441 Pharmacy and materia medica Yen, Pei Pei α1-Adrenoceptors And At1 Receptors In The Modulation Of Renal Hemodynamics In High Salt And Doca Models Of Hypertensive Rats Treated With Tempol And Losartan |
description |
Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait
rapat dengan kerosakan ginjal. Pengambilan garam lebihan menyumbang kepada
pathogenesis hipertensi. Reseptor adrenergik-α1 menyumbang kepada modulasi nada
vaskular ginjal untuk mengawal tekanan darah.
Hypertension is a major cause of morbidity and mortality from renal
impairment. An increase of sodium intake contributes to the pathogenesis of
hypertension. α1-adrenoceptors modulate renal vascular tone in the regulation of
blood pressure. This study was undertaken to investigate the effects of tempol and
losartan on renal function and haemodynamics in Sprague Dawley (SD) rats fed with
normal diet, SD rats fed with high sodium diet, DOCA-salt treated rats fed with
normal diet and DOCA-salt treated rats fed with high sodium diet. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Yen, Pei Pei |
author_facet |
Yen, Pei Pei |
author_sort |
Yen, Pei Pei |
title |
α1-Adrenoceptors And At1 Receptors In
The Modulation Of Renal
Hemodynamics In High Salt And Doca
Models Of Hypertensive Rats Treated
With Tempol And Losartan |
title_short |
α1-Adrenoceptors And At1 Receptors In
The Modulation Of Renal
Hemodynamics In High Salt And Doca
Models Of Hypertensive Rats Treated
With Tempol And Losartan |
title_full |
α1-Adrenoceptors And At1 Receptors In
The Modulation Of Renal
Hemodynamics In High Salt And Doca
Models Of Hypertensive Rats Treated
With Tempol And Losartan |
title_fullStr |
α1-Adrenoceptors And At1 Receptors In
The Modulation Of Renal
Hemodynamics In High Salt And Doca
Models Of Hypertensive Rats Treated
With Tempol And Losartan |
title_full_unstemmed |
α1-Adrenoceptors And At1 Receptors In
The Modulation Of Renal
Hemodynamics In High Salt And Doca
Models Of Hypertensive Rats Treated
With Tempol And Losartan |
title_sort |
α1-adrenoceptors and at1 receptors in
the modulation of renal
hemodynamics in high salt and doca
models of hypertensive rats treated
with tempol and losartan |
granting_institution |
Universiti Sains Malaysia |
granting_department |
Pusat Pengajian Sains Farmasi |
publishDate |
2016 |
url |
http://eprints.usm.my/32669/1/Yen_Pei_Pei.pdf |
_version_ |
1747820574582767616 |