Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.

Objective To evaluate the effectiveness and the adverse effect of Duphaston 40mg daily and Duphaston 20mg daily in threatened miscarriage. Methodology This is a prospective randomized controlled trial conducted at Hospital USM, Kubang Kerian Kelantan from 1st of March 2009 until 30th March 2010. A t...

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Main Author:	Abd Rahim, Rahimah
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RG Gynecology and obstetrics
Online Access:	http://eprints.usm.my/38097/1/Pages_from_Rahimah_Abd_Rahim-RG_GYNECOLOGY.pdf
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id	my-usm-ep.38097
record_format	uketd_dc
spelling	my-usm-ep.380972019-04-12T05:26:35Z Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm. 2011-05 Abd Rahim, Rahimah RG Gynecology and obstetrics Objective To evaluate the effectiveness and the adverse effect of Duphaston 40mg daily and Duphaston 20mg daily in threatened miscarriage. Methodology This is a prospective randomized controlled trial conducted at Hospital USM, Kubang Kerian Kelantan from 1st of March 2009 until 30th March 2010. A total of 130 patients were studied, 65 patients in Group A for those who is taking Duphaston 20mg daily and the other 65 patients in Group B on Duphaston 40mg daily. Besides the effectiveness, the side effect of the two different dosage of Duphaston is also evaluated. The successful of the pregnancy is measured by continuity of the pregnancy beyond 20weeks of gestation. Result was analysed with Chi-square and Fisher’s Exact test to determine the statistical significant. The test considered significant if p value < 0.05. Results There were higher successful pregnancy in Group B (Duphaston 40mg daily) compared to Group A (Duphaston 20mg daily) (86.7% versus 81.7%). But this is not statistically significant as the p value in multivariate analysis is 0.50 ( p> 0.05). There were no significant differences in adverse effect of the two different dosage of Duphaston. Conclusion Duphaston 40mg daily was not associated with higher chances of successful pregnancy in threatened miscarriage (p = 0.50 in multivariate analysis). There were also no significant differences of adverse effect of the drugs in between the two groups. 2011-05 Thesis http://eprints.usm.my/38097/ http://eprints.usm.my/38097/1/Pages_from_Rahimah_Abd_Rahim-RG_GYNECOLOGY.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RG Gynecology and obstetrics
spellingShingle	RG Gynecology and obstetrics Abd Rahim, Rahimah Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
description	Objective To evaluate the effectiveness and the adverse effect of Duphaston 40mg daily and Duphaston 20mg daily in threatened miscarriage. Methodology This is a prospective randomized controlled trial conducted at Hospital USM, Kubang Kerian Kelantan from 1st of March 2009 until 30th March 2010. A total of 130 patients were studied, 65 patients in Group A for those who is taking Duphaston 20mg daily and the other 65 patients in Group B on Duphaston 40mg daily. Besides the effectiveness, the side effect of the two different dosage of Duphaston is also evaluated. The successful of the pregnancy is measured by continuity of the pregnancy beyond 20weeks of gestation. Result was analysed with Chi-square and Fisher’s Exact test to determine the statistical significant. The test considered significant if p value < 0.05. Results There were higher successful pregnancy in Group B (Duphaston 40mg daily) compared to Group A (Duphaston 20mg daily) (86.7% versus 81.7%). But this is not statistically significant as the p value in multivariate analysis is 0.50 ( p> 0.05). There were no significant differences in adverse effect of the two different dosage of Duphaston. Conclusion Duphaston 40mg daily was not associated with higher chances of successful pregnancy in threatened miscarriage (p = 0.50 in multivariate analysis). There were also no significant differences of adverse effect of the drugs in between the two groups.
format	Thesis
qualification_level	Master's degree
author	Abd Rahim, Rahimah
author_facet	Abd Rahim, Rahimah
author_sort	Abd Rahim, Rahimah
title	Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
title_short	Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
title_full	Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
title_fullStr	Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
title_full_unstemmed	Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
title_sort	comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2011
url	http://eprints.usm.my/38097/1/Pages_from_Rahimah_Abd_Rahim-RG_GYNECOLOGY.pdf
_version_	1747820682709827584

Comparative study of dydrogesterone dosage of the duphaston 40mg daily and duphaston 20mg daily in the outcome of pregnancy with threatened miscarriage in husm.

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