Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress

Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress

Penuaan dan pendedahan kepada tekanan boleh menyumbang kepada kemerosotan ingatan dan kemurungan manakala stres oksidatif merupakan salah satu mekanisme yang mungkin terlibat. Pencarian penambahbaik fungsi kognitif daripada derivatif produk semulajadi yang mengandungi antioksidan semakin mendapat...

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Main Author: Azman, Khairunnuur Fairuz
Format: Thesis
Language:English
Published: 2016
Subjects:
R5-920 Medicine (General)
Online Access:http://eprints.usm.my/40850/1/Dr._Khairunnuur_Fairuz_Azman_TSTZ.pdf
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spelling my-usm-ep.408502020-05-04T02:16:16Z Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress 2016-05 Azman, Khairunnuur Fairuz R5-920 Medicine (General) Penuaan dan pendedahan kepada tekanan boleh menyumbang kepada kemerosotan ingatan dan kemurungan manakala stres oksidatif merupakan salah satu mekanisme yang mungkin terlibat. Pencarian penambahbaik fungsi kognitif daripada derivatif produk semulajadi yang mengandungi antioksidan semakin mendapat perhatian. Oleh itu, kajian ini bertujuan untuk memeriksa kesan penuaan dan tekanan ke atas prestasi ingatan dan tingkahlaku seperti kemurungan, dan menjelaskan kemungkinan mekanisme sandaran keberkesanan terapeutik madu Tualang dalam menambahbaikkan prestasi ingatan dan simptom kemurungan pada tikus jantan muda dan tua yang terdedah kepada tekanan bunyi bising. Ageing and stress exposure may lead to memory impairment and depression while oxidative stress is thought to be one of the underlying mechanisms involved. The search for cognitive enhancers from natural products derivatives possessing antioxidants has gained much attention. Thus, this study aimed to examine the effects of ageing and stress on memory performance and depressive-like behaviour, and to elucidate the possible mechanisms underlying therapeutic efficacy of Tualang honey in improving memory performance and depressive symptoms in young and old male rats exposed to loud noise stress. 2016-05 Thesis http://eprints.usm.my/40850/ http://eprints.usm.my/40850/1/Dr._Khairunnuur_Fairuz_Azman_TSTZ.pdf application/pdf en public phd doctoral USM Pusat Pengajian Sains Perubatan (School of Medical Sciences)
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Azman, Khairunnuur Fairuz
Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
description Penuaan dan pendedahan kepada tekanan boleh menyumbang kepada kemerosotan ingatan dan kemurungan manakala stres oksidatif merupakan salah satu mekanisme yang mungkin terlibat. Pencarian penambahbaik fungsi kognitif daripada derivatif produk semulajadi yang mengandungi antioksidan semakin mendapat perhatian. Oleh itu, kajian ini bertujuan untuk memeriksa kesan penuaan dan tekanan ke atas prestasi ingatan dan tingkahlaku seperti kemurungan, dan menjelaskan kemungkinan mekanisme sandaran keberkesanan terapeutik madu Tualang dalam menambahbaikkan prestasi ingatan dan simptom kemurungan pada tikus jantan muda dan tua yang terdedah kepada tekanan bunyi bising. Ageing and stress exposure may lead to memory impairment and depression while oxidative stress is thought to be one of the underlying mechanisms involved. The search for cognitive enhancers from natural products derivatives possessing antioxidants has gained much attention. Thus, this study aimed to examine the effects of ageing and stress on memory performance and depressive-like behaviour, and to elucidate the possible mechanisms underlying therapeutic efficacy of Tualang honey in improving memory performance and depressive symptoms in young and old male rats exposed to loud noise stress.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Azman, Khairunnuur Fairuz
author_facet Azman, Khairunnuur Fairuz
author_sort Azman, Khairunnuur Fairuz
title Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
title_short Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
title_full Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
title_fullStr Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
title_full_unstemmed Effects of Tualang Honey on Memory Performance, Depressive-like Behaviour, Histological and Biochemical Changes in Young and Old Male Rats Exposed to Loud Noise Stress
title_sort effects of tualang honey on memory performance, depressive-like behaviour, histological and biochemical changes in young and old male rats exposed to loud noise stress
granting_institution USM
granting_department Pusat Pengajian Sains Perubatan (School of Medical Sciences)
publishDate 2016
url http://eprints.usm.my/40850/1/Dr._Khairunnuur_Fairuz_Azman_TSTZ.pdf
_version_ 1747820833696382976

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