Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation an...
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2011
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my-usm-ep.431892019-04-12T05:26:26Z Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena 2011-11 ., Abdul Hamid QD1-999 Chemistry Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS, utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses. 2011-11 Thesis http://eprints.usm.my/43189/ http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Kimia |
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English |
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QD1-999 Chemistry |
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QD1-999 Chemistry ., Abdul Hamid Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
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Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS,
utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as
FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses. |
format |
Thesis |
qualification_name |
Doctor of Philosophy (PhD.) |
qualification_level |
Doctorate |
author |
., Abdul Hamid |
author_facet |
., Abdul Hamid |
author_sort |
., Abdul Hamid |
title |
Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
title_short |
Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
title_full |
Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
title_fullStr |
Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
title_full_unstemmed |
Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
title_sort |
phytochemical and biological investigation on three species of the genus homalomena |
granting_institution |
Universiti Sains Malaysia |
granting_department |
Pusat Pengajian Sains Kimia |
publishDate |
2011 |
url |
http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf |
_version_ |
1747821177295863808 |