Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv

Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv

M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compare...

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Main Author: Ang, Kai Cheen
Format: Thesis
Language:English
Published: 2011
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf
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spelling my-usm-ep.432262019-04-12T05:26:30Z Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv 2011-09 Ang, Kai Cheen RS1-441 Pharmacy and materia medica M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compared with its avirulent counterpart M. tuberculosis H37Ra. A total of 250 protein spots were visualized by Coomassie blue staining. The protein profiles of the M. tuberculosis H37Rv and M. tuberculosis H37Ra were highly similar (R2~0.70), thirty one spots were found to be differentially expressed at 14, 28 and 50 days cultures, whereby 14 spots were identified from Tris extract and 17 spots were identified from TLB extract. 2011-09 Thesis http://eprints.usm.my/43226/ http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Ang, Kai Cheen
Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
description M. tuberculosis H37Ra, which was discovered in 1935, was derived from the virulent strain H37. In order to identify the factors that are correlated to virulence in M. tuberculosis H37Rv, 2D-gel profile of three virulent strains at culture grown for three time points (14, 28 and 50 days) were compared with its avirulent counterpart M. tuberculosis H37Ra. A total of 250 protein spots were visualized by Coomassie blue staining. The protein profiles of the M. tuberculosis H37Rv and M. tuberculosis H37Ra were highly similar (R2~0.70), thirty one spots were found to be differentially expressed at 14, 28 and 50 days cultures, whereby 14 spots were identified from Tris extract and 17 spots were identified from TLB extract.
format Thesis
qualification_level Master's degree
author Ang, Kai Cheen
author_facet Ang, Kai Cheen
author_sort Ang, Kai Cheen
title Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
title_short Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
title_full Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
title_fullStr Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
title_full_unstemmed Comparison Of Proteomes Of Avirulent Mycobacterium Tuberculosis H37Ra And Virulent Mycobacterium Tuberculosis H37Rv
title_sort comparison of proteomes of avirulent mycobacterium tuberculosis h37ra and virulent mycobacterium tuberculosis h37rv
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2011
url http://eprints.usm.my/43226/1/ANG%20KAI%20CHEEN.pdf
_version_ 1747821181456613376

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