Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model

DNA-templated silver nanocluster (AgNC), a new promising fluorescence probe has been gaining importance in recent years. Owing to their special properties such as small in size, photostable and water-soluble, these fluorescence probes are favourable for many diagnostic applications. Due to these adv...

Full description

Saved in:
Bibliographic Details
Main Author: Lee, Shin Yong
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/43663/1/LEE%20SHIN%20YONG.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.43663
record_format uketd_dc
spelling my-usm-ep.436632019-04-12T05:24:52Z Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model 2018-02 Lee, Shin Yong R735-854 Medical education. Medical schools. Research DNA-templated silver nanocluster (AgNC), a new promising fluorescence probe has been gaining importance in recent years. Owing to their special properties such as small in size, photostable and water-soluble, these fluorescence probes are favourable for many diagnostic applications. Due to these advantages, these AgNCs were adapted to develop a method for the identification of regulatory T cells (Tregs) through an intracellular transcription factor called forkhead box P3 (Foxp3). Tregs are crucial mediators of immune homeostasis, exerting suppression on effector cells in autoimmune diseases and promoting the cancer growth. 2018-02 Thesis http://eprints.usm.my/43663/ http://eprints.usm.my/43663/1/LEE%20SHIN%20YONG.pdf application/pdf en public masters Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Lee, Shin Yong
Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
description DNA-templated silver nanocluster (AgNC), a new promising fluorescence probe has been gaining importance in recent years. Owing to their special properties such as small in size, photostable and water-soluble, these fluorescence probes are favourable for many diagnostic applications. Due to these advantages, these AgNCs were adapted to develop a method for the identification of regulatory T cells (Tregs) through an intracellular transcription factor called forkhead box P3 (Foxp3). Tregs are crucial mediators of immune homeostasis, exerting suppression on effector cells in autoimmune diseases and promoting the cancer growth.
format Thesis
qualification_level Master's degree
author Lee, Shin Yong
author_facet Lee, Shin Yong
author_sort Lee, Shin Yong
title Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
title_short Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
title_full Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
title_fullStr Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
title_full_unstemmed Development Of A Silver Nanocluster Probe Against Foxp3 For Live Tregs Sorting : Using MCF-7 As A Model
title_sort development of a silver nanocluster probe against foxp3 for live tregs sorting : using mcf-7 as a model
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2018
url http://eprints.usm.my/43663/1/LEE%20SHIN%20YONG.pdf
_version_ 1747821257915629568