Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect

Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia s...

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Main Author:	Torey, Angeline Torey Ayah
Format:	Thesis
Language:	English
Published:	2012
Subjects:	R735-854 Medical education Medical schools Research
Online Access:	http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf
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id	my-usm-ep.44778
record_format	uketd_dc
spelling	my-usm-ep.447782019-07-01T02:23:57Z Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect 2012-07 Torey, Angeline Torey Ayah R735-854 Medical education. Medical schools. Research Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia spectabilis leaves was evaluated against biofilm-forming C. albicans with the mechanisms of action. The leaf extract was first standardized in terms of authenticity, assay and chemical constituent analysis. Then the antifungal activity of the extract against C. albicans was established by using the disk diffusion and minimum inhibitory concentration (MIC) assay using the broth macrodilution method. 2012-07 Thesis http://eprints.usm.my/44778/ http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf application/pdf en public masters Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R735-854 Medical education Medical schools Research
spellingShingle	R735-854 Medical education Medical schools Research Torey, Angeline Torey Ayah Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
description	Candida albicans in its biofilm mode of growth is increasingly attracting interest in its role in human infections due to the development of resistance to commonly-used antibiotics or phenotypic adaptation within the biofilm. Hence, in this study the inhibitory effect of methanol extract of Cassia spectabilis leaves was evaluated against biofilm-forming C. albicans with the mechanisms of action. The leaf extract was first standardized in terms of authenticity, assay and chemical constituent analysis. Then the antifungal activity of the extract against C. albicans was established by using the disk diffusion and minimum inhibitory concentration (MIC) assay using the broth macrodilution method.
format	Thesis
qualification_level	Master's degree
author	Torey, Angeline Torey Ayah
author_facet	Torey, Angeline Torey Ayah
author_sort	Torey, Angeline Torey Ayah
title	Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_short	Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_full	Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_fullStr	Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_full_unstemmed	Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect
title_sort	possible mechanisms of action and inhibition of biofilm by cassia spectabilis (dc.) methanol leaf extract on candida albicans cells and the cytotoxicity effect
granting_institution	Universiti Sains Malaysia
granting_department	Institut Penyelidikan Perubatan Molekul
publishDate	2012
url	http://eprints.usm.my/44778/1/ANGELINE%20TOREY%20AYAH%20TOREY.pdf
_version_	1747821396598194176

Possible Mechanisms Of Action And Inhibition Of Biofilm By Cassia Spectabilis (DC.) Methanol Leaf Extract On Candida Albicans Cells And The Cytotoxicity Effect

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