The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies

The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies

Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on...

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Main Author: Ab Patar, Mohd Nor Azim
Format: Thesis
Language:English
Published: 2012
Subjects:
R5-920 Medicine (General)
Online Access:http://eprints.usm.my/44845/1/MOHD%20NOR%20AZIM%20AB%20PATAR.pdf
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spelling my-usm-ep.448452019-07-03T07:19:38Z The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies 2012-06 Ab Patar, Mohd Nor Azim R5-920 Medicine (General) Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on the central nervous system. In the present study, Stichopus variegatus (SV) were harvested, processed and extracted in the laboratory and were evaluated on their proliferative activity on rat astrocytes cell lines (in vitro), as well as contusive spinal cord injury in a rat model (in vivo). In vitro analysis of SV extract showed proliferative activity of rat astrocytes cell line at 5 μg/ml and 10 μg/ml. 2012-06 Thesis http://eprints.usm.my/44845/ http://eprints.usm.my/44845/1/MOHD%20NOR%20AZIM%20AB%20PATAR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Ab Patar, Mohd Nor Azim
The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
description Sea cucumbers from Pulau Perhentian, Malaysia are well known as potential marine edible food sources and possess medicinal value to the Malaysian community. Despite the presence of small industries and its usage amongst local folks, there is little work done on its biological activity, especially on the central nervous system. In the present study, Stichopus variegatus (SV) were harvested, processed and extracted in the laboratory and were evaluated on their proliferative activity on rat astrocytes cell lines (in vitro), as well as contusive spinal cord injury in a rat model (in vivo). In vitro analysis of SV extract showed proliferative activity of rat astrocytes cell line at 5 μg/ml and 10 μg/ml.
format Thesis
qualification_level Master's degree
author Ab Patar, Mohd Nor Azim
author_facet Ab Patar, Mohd Nor Azim
author_sort Ab Patar, Mohd Nor Azim
title The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
title_short The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
title_full The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
title_fullStr The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
title_full_unstemmed The Effects Of Stichopus Variegatus Crude Extracts On Acute Contusive Rat Spinal Cord Injury Model : In Vitro And In Vivo Studies
title_sort effects of stichopus variegatus crude extracts on acute contusive rat spinal cord injury model : in vitro and in vivo studies
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2012
url http://eprints.usm.my/44845/1/MOHD%20NOR%20AZIM%20AB%20PATAR.pdf
_version_ 1747821411196469248

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