Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi
Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for fur...
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my-usm-ep.450752019-07-26T01:25:56Z Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi 2014-12 Kumar, Thiviyaa M. Othaya R735-854 Medical education. Medical schools. Research Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by LocaRNA software. 2014-12 Thesis http://eprints.usm.my/45075/ http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju |
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English |
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R735-854 Medical education Medical schools Research |
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R735-854 Medical education Medical schools Research Kumar, Thiviyaa M. Othaya Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| description |
Non-protein-coding RNAs (npcRNAs) are RNA molecules that do not encode for proteins but are involved in modulating a myriad of cell regulatory processes, including bacterial drug resistance mechanisms. In this study, a novel npcRNA, StyR-3; discovered from the genome of S. Typhi was selected for further characterization via bioinformatics and experimental-based approaches. This 144-nt intergenic npcRNA is located in the ramRA regulon of S. Typhi Ty2. The bioinformatics-based characterization showed that it is highly conserved among Salmonella species; besides having a stable secondary structure as was predicted by
LocaRNA software. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Kumar, Thiviyaa M. Othaya |
| author_facet |
Kumar, Thiviyaa M. Othaya |
| author_sort |
Kumar, Thiviyaa M. Othaya |
| title |
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_short |
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_full |
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_fullStr |
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_full_unstemmed |
Functional Characterization Of Styr-3 Non-Protein-Coding Rna (npcRNA) In Salmonella enterica serovar Typhi |
| title_sort |
functional characterization of styr-3 non-protein-coding rna (npcrna) in salmonella enterica serovar typhi |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Institut Perubatan & Pergigian Termaju |
| publishDate |
2014 |
| url |
http://eprints.usm.my/45075/1/THIVIYAA%20M.%20OTHAYA%20KUMAR.pdf |
| _version_ |
1747821451181817856 |