Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves

Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and sti...

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Main Author:	Farsi, Elham
Format:	Thesis
Language:	English
Published:	2017
Subjects:	L7-991 Education (General)
Online Access:	http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf
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id	my-usm-ep.45376
record_format	uketd_dc
spelling	my-usm-ep.453762019-09-11T01:15:56Z Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves 2017-01 Farsi, Elham L7-991 Education (General) Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity. 2017-01 Thesis http://eprints.usm.my/45376/ http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Ilmu Pendidikan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	L7-991 Education (General)
spellingShingle	L7-991 Education (General) Farsi, Elham Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
description	Cisplatin is an effective chemotherapeutic agent for solid tumors. However, it also induces dose-dependent progressive and irreversible nephrotoxicity. Cisplatin has multiple intracellular effects, which includes causing direct cytotoxicity with reactive oxygen species, activating apoptosis, and stimulating inflammation, events of which cause vascular and tubular dysfunction. Animal models have demonstrated that cisplatin-induced renal toxicity is characterized by a rapid loss of glomerular filtration, polyuria, hyperkalemia, hypernatremia, and azotemia. Recently, much attention has been given to the possible role of herbal medicine in protecting against cisplatin-induced renal toxicity.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Farsi, Elham
author_facet	Farsi, Elham
author_sort	Farsi, Elham
title	Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_short	Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_full	Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_fullStr	Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_full_unstemmed	Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves
title_sort	nephroprotective effect of clinacanhus nutans, orthosiphon stamineus, and syzyguim camponulatum leaves against cisplatin-induced nephrotoxcity; and safety asseement of clinacathus nutans leaves
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Ilmu Pendidikan
publishDate	2017
url	http://eprints.usm.my/45376/1/ELHAM%20FARSI.pdf
_version_	1747821497454428160

Nephroprotective Effect Of Clinacanhus Nutans, Orthosiphon Stamineus, And Syzyguim Camponulatum Leaves Against Cisplatin-Induced Nephrotoxcity; And Safety Asseement Of Clinacathus Nutans Leaves

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