Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men

Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men

INTRODUCTION: Proper immune function and healthy bone is required for maintaining daily routine of an individual. To date, no study has been carried out to investigate possible benefits of Moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover mar...

Full description

Saved in:
Bibliographic Details
Main Author: Muin, Maziana Abdul
Format: Thesis
Language:English
Published: 2018
Subjects:
R Medicine
Online Access:http://eprints.usm.my/46231/1/Dr.%20Maziana%20Abdul%20Muin-24%20pages.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.46231
record_format uketd_dc
spelling my-usm-ep.462312020-02-16T03:27:45Z Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men 2018-05 Muin, Maziana Abdul R Medicine INTRODUCTION: Proper immune function and healthy bone is required for maintaining daily routine of an individual. To date, no study has been carried out to investigate possible benefits of Moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men. PURPOSE: Therefore, the present study was carried out to determine the effects of Moringa oleifera supplementation combined with resistance exercise (MOEx) compared to Moringa oleifera supplementation alone (MO), resistance exercise alone (Ex) and control (C) groups on immune responses and bone turnover markers among young men. METHODS: Forty sedentary young men (age: 22.1 ± 1.3 years old) were recruited and were randomised into four separate groups: placebo without exercise control (C), resistance exercise alone (Ex), Moringa oleifera supplementation alone (MO) and resistance exercise with Moringa oleifera supplementation (MOEx). Participants in the Ex and MOEx groups performed resistance exercise 3 times per week for 6 weeks which consisted of 10 different exercises. Participants were required to perform 3 sets of 10-15 repetitions of resistance exercise per set. Participants in the MO and MOEx groups consumed Moringa oleifera (300 mg of 100% Moringa oleifera leaf powder each capsule) and participants in the C and Ex groups consumed placebo twice daily for 6 weeks. Participants’ body height, weight, blood pressure andresting heart rate were measured at pre- and post-tests. Blood samples were collected at pre- and post-tests after an overnight fast. Blood samples were used to analyse total WBC, lymphocytes, monocyte, T lymphocyte (CD3+, CD4+ and CD8+) and B lymphocyte (CD19+) counts. Blood samples were also used to analyse concentrations of alkaline phosphatase (ALP), osteocalcin (OC) and cross-linked C-terminal telopeptide of collagen alpha-1 (1CTP). A mixed analysis of variance (ANOVA) was performed to determine the significance of the differences between and within groups. RESULTS: It was found that combination of resistance exercise and Moringa oleifera did not significantly (p > 0.05) induce better effects on immune responses and bone turnover markers concentration compared to control, resistance exercise alone, and MO supplementation alone. CONCLUSION: Six weeks of combined MO supplementation and resistance exercise did not significantly enhance immune responses and bone turnover markers among sedentary young men. 2018-05 Thesis http://eprints.usm.my/46231/ http://eprints.usm.my/46231/1/Dr.%20Maziana%20Abdul%20Muin-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine
spellingShingle R Medicine
Muin, Maziana Abdul
Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
description INTRODUCTION: Proper immune function and healthy bone is required for maintaining daily routine of an individual. To date, no study has been carried out to investigate possible benefits of Moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men. PURPOSE: Therefore, the present study was carried out to determine the effects of Moringa oleifera supplementation combined with resistance exercise (MOEx) compared to Moringa oleifera supplementation alone (MO), resistance exercise alone (Ex) and control (C) groups on immune responses and bone turnover markers among young men. METHODS: Forty sedentary young men (age: 22.1 ± 1.3 years old) were recruited and were randomised into four separate groups: placebo without exercise control (C), resistance exercise alone (Ex), Moringa oleifera supplementation alone (MO) and resistance exercise with Moringa oleifera supplementation (MOEx). Participants in the Ex and MOEx groups performed resistance exercise 3 times per week for 6 weeks which consisted of 10 different exercises. Participants were required to perform 3 sets of 10-15 repetitions of resistance exercise per set. Participants in the MO and MOEx groups consumed Moringa oleifera (300 mg of 100% Moringa oleifera leaf powder each capsule) and participants in the C and Ex groups consumed placebo twice daily for 6 weeks. Participants’ body height, weight, blood pressure andresting heart rate were measured at pre- and post-tests. Blood samples were collected at pre- and post-tests after an overnight fast. Blood samples were used to analyse total WBC, lymphocytes, monocyte, T lymphocyte (CD3+, CD4+ and CD8+) and B lymphocyte (CD19+) counts. Blood samples were also used to analyse concentrations of alkaline phosphatase (ALP), osteocalcin (OC) and cross-linked C-terminal telopeptide of collagen alpha-1 (1CTP). A mixed analysis of variance (ANOVA) was performed to determine the significance of the differences between and within groups. RESULTS: It was found that combination of resistance exercise and Moringa oleifera did not significantly (p > 0.05) induce better effects on immune responses and bone turnover markers concentration compared to control, resistance exercise alone, and MO supplementation alone. CONCLUSION: Six weeks of combined MO supplementation and resistance exercise did not significantly enhance immune responses and bone turnover markers among sedentary young men.
format Thesis
qualification_level Master's degree
author Muin, Maziana Abdul
author_facet Muin, Maziana Abdul
author_sort Muin, Maziana Abdul
title Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
title_short Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
title_full Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
title_fullStr Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
title_full_unstemmed Effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
title_sort effects of moringa oleifera supplementation combined with resistance exercise on immune responses and bone turnover markers among young men
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2018
url http://eprints.usm.my/46231/1/Dr.%20Maziana%20Abdul%20Muin-24%20pages.pdf
_version_ 1747821632875921408

Similar Items