Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction

Craniofacial defect is typically unique and depend on the anatomical condition of the patient for which patient specific implant (PSI) is desirable. The FDM based 3D printer could be utilised to cater the needs. However, the commercially available feedstock is bio-incompatible and lack of mechani...

Full description

Saved in:

Bibliographic Details
Main Author:	Abdullah, Abdul Manaf
Format:	Thesis
Language:	English
Published:	2020
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/47883/1/01.%20ABDUL%20MANAF%20BIN%20ABDULLAH-FINAL%20THESIS%20PWD%20P-SGD000217%28R%29-24%20pages.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.47883
record_format	uketd_dc
spelling	my-usm-ep.478832020-11-09T07:15:18Z Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction 2020-06 Abdullah, Abdul Manaf R Medicine Craniofacial defect is typically unique and depend on the anatomical condition of the patient for which patient specific implant (PSI) is desirable. The FDM based 3D printer could be utilised to cater the needs. However, the commercially available feedstock is bio-incompatible and lack of mechanical integrity which hinder the application. This study aimed to develop a new polyamide 6 based filament feedstock aiming for craniofacial reconstruction. Polyamide 6 was compounded with carbon fibre and zinc oxide prior to filament feedstock fabrication and 3D printing processes. The effect of carbon fibre as well as hybrid carbon fibre/zinc oxide incorporation on the physicochemical properties of the compounds as well mechanical and biological properties of the 3D printed parts were assessed. The melting temperature of the composites were not affected by the filler incorporation, however, the melt flow rate, tensile, compressive and surface roughness properties of the PA 6 composites increased appreciably. The composites also exhibited better toughness properties than unfilled PA 6 after 60 days of immersion in simulated body fluid despite of high moisture absorption. The viability of osteoblast cells were more than 70% following treatment with extracted composites at concentrations of 50, 25, 12.5 and 6.25 mg/ml. The composites also demonstrated appreciable antibacterial effect against Grampositive and negative bacteria of Staphylococcus aureus and Pseudomonas aeruginosa. However, the effect was selective and more pronounced in S. aureus. The newly developed polyamide 6 based filament feedstock is compatible to be used with FDM based 3D printer. With enhanced mechanical and biological properties, the developed composites are potential to be used for craniofacial reconstruction. 2020-06 Thesis http://eprints.usm.my/47883/ http://eprints.usm.my/47883/1/01.%20ABDUL%20MANAF%20BIN%20ABDULLAH-FINAL%20THESIS%20PWD%20P-SGD000217%28R%29-24%20pages.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Abdullah, Abdul Manaf Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
description	Craniofacial defect is typically unique and depend on the anatomical condition of the patient for which patient specific implant (PSI) is desirable. The FDM based 3D printer could be utilised to cater the needs. However, the commercially available feedstock is bio-incompatible and lack of mechanical integrity which hinder the application. This study aimed to develop a new polyamide 6 based filament feedstock aiming for craniofacial reconstruction. Polyamide 6 was compounded with carbon fibre and zinc oxide prior to filament feedstock fabrication and 3D printing processes. The effect of carbon fibre as well as hybrid carbon fibre/zinc oxide incorporation on the physicochemical properties of the compounds as well mechanical and biological properties of the 3D printed parts were assessed. The melting temperature of the composites were not affected by the filler incorporation, however, the melt flow rate, tensile, compressive and surface roughness properties of the PA 6 composites increased appreciably. The composites also exhibited better toughness properties than unfilled PA 6 after 60 days of immersion in simulated body fluid despite of high moisture absorption. The viability of osteoblast cells were more than 70% following treatment with extracted composites at concentrations of 50, 25, 12.5 and 6.25 mg/ml. The composites also demonstrated appreciable antibacterial effect against Grampositive and negative bacteria of Staphylococcus aureus and Pseudomonas aeruginosa. However, the effect was selective and more pronounced in S. aureus. The newly developed polyamide 6 based filament feedstock is compatible to be used with FDM based 3D printer. With enhanced mechanical and biological properties, the developed composites are potential to be used for craniofacial reconstruction.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Abdullah, Abdul Manaf
author_facet	Abdullah, Abdul Manaf
author_sort	Abdullah, Abdul Manaf
title	Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
title_short	Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
title_full	Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
title_fullStr	Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
title_full_unstemmed	Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction
title_sort	preparation and characterisation of 3d printed polyamide 6 composites for craniofacial reconstruction
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/47883/1/01.%20ABDUL%20MANAF%20BIN%20ABDULLAH-FINAL%20THESIS%20PWD%20P-SGD000217%28R%29-24%20pages.pdf
_version_	1747821843649134592

Preparation and characterisation of 3D printed polyamide 6 composites for craniofacial reconstruction

Similar Items