Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial

Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare t...

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Main Author:	Helmi, Muhd Alwi Muhd
Format:	Thesis
Language:	English
Published:	2020
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf
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spelling	my-usm-ep.503062021-10-18T05:52:42Z Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial 2020 Helmi, Muhd Alwi Muhd R Medicine Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between Continuous Glucose Monitoring System (CGMS) and Self-Monitoring Blood Glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children. 2020 Thesis http://eprints.usm.my/50306/ http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Helmi, Muhd Alwi Muhd Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
description	Background A single centre, randomized, parallel-group controlled trial was conducted involving twenty-two type one Diabetes Mellitus (T1DM) patients with the mean age of 13.8 years assigned to either intervention or control group. Objectives The primary and secondary objectives were to compare the glycaemic control and frequency of hypoglycaemia between Continuous Glucose Monitoring System (CGMS) and Self-Monitoring Blood Glucose (SMBG). Intervention All respondents wore the CGMS device at the beginning of the study. Intervention group (n=11) had their insulin adjusted based on the CGMS data, while the control group (n=11) were based on SMBG. Monthly average blood sugar level (BSL) and monthly mean hypoglycemic events per week (HE/wk) were measured at baseline, first month, the second month, and third month. HbA1c levels were measured at baseline and in the third month. Results The baseline characteristics were similar. The data were analysed using repeated measure analysis of variance (ANOVA). The mean difference of HbA1c within the group was not statistically significant with p=0.322. There were significant differences in the monthly mean HE/wk within and between groups, p=0.004, and p=0.037. Conclusion In conclusion, CGMS is equivalent to SMBG in optimising glycaemic control but is more effective in detecting hypoglycaemia in children.
format	Thesis
qualification_level	Master's degree
author	Helmi, Muhd Alwi Muhd
author_facet	Helmi, Muhd Alwi Muhd
author_sort	Helmi, Muhd Alwi Muhd
title	Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_short	Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_full	Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_fullStr	Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_full_unstemmed	Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial
title_sort	continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (rosec) : a randomized controlled trial
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/50306/1/Muhd%20Alwi%20Muhd%20Helmi-24%20pages.pdf
_version_	1747822031964995584

Continuous glucose monitoring system versus self-monitoring blood glucose in type 1 diabetes children (RoSEC) : a randomized controlled trial

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