The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema

Objective: To compare the efficacy and safety of intravitreal triamcinolone injection to laser photocoagulation in the primary treatment of diabetic macular oedema. Methodology: Forty patients with newly diagnosed diabetic macular oedema were randomized into 2 groups 20 in 4mg intravitreal triamc...

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Main Author:	Mustafa, Norlaili
Format:	Thesis
Language:	English
Published:	2008
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/50831/1/DR.%20NORLAILI%20BINTI%20MUSTAFA-24%20pages.pdf
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spelling	my-usm-ep.508312021-12-06T08:53:44Z The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema 2008 Mustafa, Norlaili R Medicine Objective: To compare the efficacy and safety of intravitreal triamcinolone injection to laser photocoagulation in the primary treatment of diabetic macular oedema. Methodology: Forty patients with newly diagnosed diabetic macular oedema were randomized into 2 groups 20 in 4mg intravitreal triamcinolone acetonide (IVT A) injection of and 20 in laser photocoagulation group. Evaluation was done at three months and the macular oedema was quantified using HRT II. Intraocular pressure elevation, lenticular opacity and endophthalmitis were observed. Results: Mean visual acuity for IVTA group was 0.935(0.223) at baseline and 0.405(0.223) at three months, p<0.01. Mean visual acuity for laser group was 0.795(0.315) at baseline and 0.525(0.289) at three months, p<0.01. However, there was no statistically significant difference between the two groups, p=0.151. Mean macular oedema index for IVTA group was 2.539 (0.914) at baseline and 1.753 (0.577) at three months, p<0.01. Mean macular oedema index for laser group was 2.139 (0.577) at baseline and 1.711(0.472) at three months, p<0.01. However, there was no statistically significant difference between the two groups (p=0.811 ). The mean intraocular pressure was statistically significant pre and post IVT A injection (p=0.032). There was no significant cataract progression at three months in both groups, p=0.688 and no incidence of endophthalmitis post IVT A injection at three months review. Conclusion: Both IVT A and laser photocoagulation demonstrate good outcome as primary treatment in diabetic macular oedema patients. The IVTA is a relatively safe procedure. 2008 Thesis http://eprints.usm.my/50831/ http://eprints.usm.my/50831/1/DR.%20NORLAILI%20BINTI%20MUSTAFA-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Mustafa, Norlaili The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
description	Objective: To compare the efficacy and safety of intravitreal triamcinolone injection to laser photocoagulation in the primary treatment of diabetic macular oedema. Methodology: Forty patients with newly diagnosed diabetic macular oedema were randomized into 2 groups 20 in 4mg intravitreal triamcinolone acetonide (IVT A) injection of and 20 in laser photocoagulation group. Evaluation was done at three months and the macular oedema was quantified using HRT II. Intraocular pressure elevation, lenticular opacity and endophthalmitis were observed. Results: Mean visual acuity for IVTA group was 0.935(0.223) at baseline and 0.405(0.223) at three months, p<0.01. Mean visual acuity for laser group was 0.795(0.315) at baseline and 0.525(0.289) at three months, p<0.01. However, there was no statistically significant difference between the two groups, p=0.151. Mean macular oedema index for IVTA group was 2.539 (0.914) at baseline and 1.753 (0.577) at three months, p<0.01. Mean macular oedema index for laser group was 2.139 (0.577) at baseline and 1.711(0.472) at three months, p<0.01. However, there was no statistically significant difference between the two groups (p=0.811 ). The mean intraocular pressure was statistically significant pre and post IVT A injection (p=0.032). There was no significant cataract progression at three months in both groups, p=0.688 and no incidence of endophthalmitis post IVT A injection at three months review. Conclusion: Both IVT A and laser photocoagulation demonstrate good outcome as primary treatment in diabetic macular oedema patients. The IVTA is a relatively safe procedure.
format	Thesis
qualification_level	Master's degree
author	Mustafa, Norlaili
author_facet	Mustafa, Norlaili
author_sort	Mustafa, Norlaili
title	The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
title_short	The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
title_full	The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
title_fullStr	The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
title_full_unstemmed	The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
title_sort	efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2008
url	http://eprints.usm.my/50831/1/DR.%20NORLAILI%20BINTI%20MUSTAFA-24%20pages.pdf
_version_	1747822046669176832

The efficacy of intravitreal triamcinolone versus aser photocoagulation in the primary treament of diabetic macular oedema

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