A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns

A Randomised Control Trial comparing the effects of Honey versus Sucrose as analgesia during routine venepuncture in newbom To dctennine the effectiveness and short term side effects of honey as analgesia in comparison to sucrose during routine venepuncture in newborn. A total of 78 tenn neonates...

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Main Author: Khanisa, Md Khalid
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.usm.my/55111/1/DR%20KHANISA%20MD%20KHALID%20-%2024%20pages.pdf
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spelling my-usm-ep.551112022-10-04T06:35:33Z A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns 2011 Khanisa, Md Khalid R Medicine (General) A Randomised Control Trial comparing the effects of Honey versus Sucrose as analgesia during routine venepuncture in newbom To dctennine the effectiveness and short term side effects of honey as analgesia in comparison to sucrose during routine venepuncture in newborn. A total of 78 tenn neonates were recmited from the Neonatal Intensive Care Unit and Special Care Nursery of Hospital Universiti Sains Malaysia. These neonates were randomized into two equal sized group receiving either 2 ml of oral 24% sucrose or 2 ml of Tualang honey 2 minutes prior to venepuncture. The whole procedure was videotaped. The degree of pain score using PIPP and duration of crying time were determined twice by two independent observer. The Mann Whitney U test was used to compare the pain scores and duration of cry between the study groups while the Wilcoxon sign rank test was used to compare differences within each group. The result showed no significant differences in the demographic characteristics of the neonates. The median values of PIPP at 30 seconds and 150 seconds were comparable (p value = 0.871) between both groups (median PIPP sucrose = 5, 3 median PIPP for honey = 5, 2 respectively). The median PIPP score within each group was significantly higher (p value= 0.00) at 30 seconds (median =5) compared to at 150 seconds (median = 2.5). The duration of audible cry after venepuncture was not statistically significant {p=0.803) in neonates receiving honey (median= 5.5 seconds) compared to neonates receiving 24% sucrose (median = 4 seconds). No neonates developed hyperglycemia, diarrhea or glycosuria in this study. The result showed no significant differences in the demographic characteristics of the neonates. The median values of PIPP at 30 seconds and 150 seconds were comparable (p value = 0.871) between both groups (median PIPP sucrose = 5, 3 median PIPP for honey = 5, 2 respectively). The median PIPP score within each group was significantly higher (p value= 0.00) at 30 seconds (median =5) compared to at 150 seconds (median = 2.5). The duration of audible cry after venepuncture was not statistically significant {p=0.803) in neonates receiving honey (median= 5.5 seconds) compared to neonates receiving 24% sucrose (median = 4 seconds). No neonates developed hyperglycemia, diarrhea or glycosuria in this study. 2011 Thesis http://eprints.usm.my/55111/ http://eprints.usm.my/55111/1/DR%20KHANISA%20MD%20KHALID%20-%2024%20pages.pdf application/pdf en public masters Pusat Pengajian Sains Perubatan PPSP Universiti Sains Malaysia
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Khanisa, Md Khalid
A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
description A Randomised Control Trial comparing the effects of Honey versus Sucrose as analgesia during routine venepuncture in newbom To dctennine the effectiveness and short term side effects of honey as analgesia in comparison to sucrose during routine venepuncture in newborn. A total of 78 tenn neonates were recmited from the Neonatal Intensive Care Unit and Special Care Nursery of Hospital Universiti Sains Malaysia. These neonates were randomized into two equal sized group receiving either 2 ml of oral 24% sucrose or 2 ml of Tualang honey 2 minutes prior to venepuncture. The whole procedure was videotaped. The degree of pain score using PIPP and duration of crying time were determined twice by two independent observer. The Mann Whitney U test was used to compare the pain scores and duration of cry between the study groups while the Wilcoxon sign rank test was used to compare differences within each group. The result showed no significant differences in the demographic characteristics of the neonates. The median values of PIPP at 30 seconds and 150 seconds were comparable (p value = 0.871) between both groups (median PIPP sucrose = 5, 3 median PIPP for honey = 5, 2 respectively). The median PIPP score within each group was significantly higher (p value= 0.00) at 30 seconds (median =5) compared to at 150 seconds (median = 2.5). The duration of audible cry after venepuncture was not statistically significant {p=0.803) in neonates receiving honey (median= 5.5 seconds) compared to neonates receiving 24% sucrose (median = 4 seconds). No neonates developed hyperglycemia, diarrhea or glycosuria in this study. The result showed no significant differences in the demographic characteristics of the neonates. The median values of PIPP at 30 seconds and 150 seconds were comparable (p value = 0.871) between both groups (median PIPP sucrose = 5, 3 median PIPP for honey = 5, 2 respectively). The median PIPP score within each group was significantly higher (p value= 0.00) at 30 seconds (median =5) compared to at 150 seconds (median = 2.5). The duration of audible cry after venepuncture was not statistically significant {p=0.803) in neonates receiving honey (median= 5.5 seconds) compared to neonates receiving 24% sucrose (median = 4 seconds). No neonates developed hyperglycemia, diarrhea or glycosuria in this study.
format Thesis
qualification_level Master's degree
author Khanisa, Md Khalid
author_facet Khanisa, Md Khalid
author_sort Khanisa, Md Khalid
title A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
title_short A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
title_full A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
title_fullStr A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
title_full_unstemmed A randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
title_sort randomised controlled trial comparing the effects of honey versus sucrose as an analgesia during routine venepuncture in newborns
granting_institution Pusat Pengajian Sains Perubatan
granting_department PPSP Universiti Sains Malaysia
publishDate 2011
url http://eprints.usm.my/55111/1/DR%20KHANISA%20MD%20KHALID%20-%2024%20pages.pdf
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