Review of CHESS score in SAH patients in local Malaysian population

Background and Objective Chronic hydrocephalus caused by subarachnoid hemorrhage is a reversible and treatable condition. To date, existing clinical scores for predicting the development of posthemorrhagic hydrocephalus are few and difficult to apply in the clinical settings. Chronic Hydrocephal...

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Main Author:	Sze-Voon, Yee
Format:	Thesis
Language:	English
Published:	2018
Subjects:	R Medicine
Online Access:	http://eprints.usm.my/56776/1/Dr.%20Yee%20Sze-Voon-24%20pages.pdf
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spelling	my-usm-ep.567762023-02-08T07:57:12Z Review of CHESS score in SAH patients in local Malaysian population 2018 Sze-Voon, Yee R Medicine Background and Objective Chronic hydrocephalus caused by subarachnoid hemorrhage is a reversible and treatable condition. To date, existing clinical scores for predicting the development of posthemorrhagic hydrocephalus are few and difficult to apply in the clinical settings. Chronic Hydrocephalus Ensuing Subarachnoid Hemorrhage Score (CHESS) was first published in 2015. Although it showed promising results, no external validation has been done outside Europe. We designed this study to validate the accuracy and reliability of CHESS score and to also look for other factors that may cause post-hemorrhagic shunt dependent hydrocephalus. Methods A total of 130 patients with acute subarachnoid haemorrhage from 2 tertiary neurosurgery centres in Malaysia were analysed using the parameters in CHESS score. The CHESS score was applied retrospectively and the results were compared with the patients’ clinical data of development of shunt-dependent hydrocephalus. Results were analysed using binary logistic regression analysis and Goodness-of-Fit test to determine the predictive value and its distribution with the original data. Results Thirty one percent of the studied population developed shunt-dependent hydrocephalus (n=41). CHESS score showed a OR of 2.184 with p value of 0.000 and 2 other risk factors were found to be strongly related to development of shunt-dependent hydrocephalus i.e. early infarct in CT brain (OR 0.182 ; p value 0.004) and Fisher grade >3 (OR 1.986; p value of 0.047). However, the population distribution of CHESS score is not consistent with the data of the original author. Conclusion CHESS score is a reliable tool in early prediction of shunt-dependent hydrocephalus post subarachnoid haemorrhage in Malaysia. 2018 Thesis http://eprints.usm.my/56776/ http://eprints.usm.my/56776/1/Dr.%20Yee%20Sze-Voon-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine
spellingShingle	R Medicine Sze-Voon, Yee Review of CHESS score in SAH patients in local Malaysian population
description	Background and Objective Chronic hydrocephalus caused by subarachnoid hemorrhage is a reversible and treatable condition. To date, existing clinical scores for predicting the development of posthemorrhagic hydrocephalus are few and difficult to apply in the clinical settings. Chronic Hydrocephalus Ensuing Subarachnoid Hemorrhage Score (CHESS) was first published in 2015. Although it showed promising results, no external validation has been done outside Europe. We designed this study to validate the accuracy and reliability of CHESS score and to also look for other factors that may cause post-hemorrhagic shunt dependent hydrocephalus. Methods A total of 130 patients with acute subarachnoid haemorrhage from 2 tertiary neurosurgery centres in Malaysia were analysed using the parameters in CHESS score. The CHESS score was applied retrospectively and the results were compared with the patients’ clinical data of development of shunt-dependent hydrocephalus. Results were analysed using binary logistic regression analysis and Goodness-of-Fit test to determine the predictive value and its distribution with the original data. Results Thirty one percent of the studied population developed shunt-dependent hydrocephalus (n=41). CHESS score showed a OR of 2.184 with p value of 0.000 and 2 other risk factors were found to be strongly related to development of shunt-dependent hydrocephalus i.e. early infarct in CT brain (OR 0.182 ; p value 0.004) and Fisher grade >3 (OR 1.986; p value of 0.047). However, the population distribution of CHESS score is not consistent with the data of the original author. Conclusion CHESS score is a reliable tool in early prediction of shunt-dependent hydrocephalus post subarachnoid haemorrhage in Malaysia.
format	Thesis
qualification_level	Master's degree
author	Sze-Voon, Yee
author_facet	Sze-Voon, Yee
author_sort	Sze-Voon, Yee
title	Review of CHESS score in SAH patients in local Malaysian population
title_short	Review of CHESS score in SAH patients in local Malaysian population
title_full	Review of CHESS score in SAH patients in local Malaysian population
title_fullStr	Review of CHESS score in SAH patients in local Malaysian population
title_full_unstemmed	Review of CHESS score in SAH patients in local Malaysian population
title_sort	review of chess score in sah patients in local malaysian population
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2018
url	http://eprints.usm.my/56776/1/Dr.%20Yee%20Sze-Voon-24%20pages.pdf
_version_	1776101171217301504

Review of CHESS score in SAH patients in local Malaysian population

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