A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes

Introduction: The incidence of twin pregnancy is increasing worldwide1, and so does in Malaysia. It is associated with a higher risk of morbidity and mortality throughout pregnancy to both mother and fetus. This study aims to determine the maternal and fetal characteristic of twin pregnancies in Hos...

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Main Author:	Nor, Nurliza Md
Format:	Thesis
Language:	English
Published:	2020
Subjects:	RG551-591 Pregnancy
Online Access:	http://eprints.usm.my/57330/1/DR%20NURLIZA%20BINTI%20MD%20NOR-24%20pages.pdf
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spelling	my-usm-ep.573302023-11-21T06:27:53Z A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes 2020 Nor, Nurliza Md RG551-591 Pregnancy Introduction: The incidence of twin pregnancy is increasing worldwide1, and so does in Malaysia. It is associated with a higher risk of morbidity and mortality throughout pregnancy to both mother and fetus. This study aims to determine the maternal and fetal characteristic of twin pregnancies in Hospital Sultan Ismail Johor Bahru (HSIJB) and to observe the association between the gestational age at delivery and the delivery outcomes in uncomplicated twin pregnancies. Methodology: This is a retrospective observational study of women with uncomplicated monochorionic and dichorionic twin pregnancies delivered at 36 completed weeks or beyond from January 2009 until December 2018 in HSIJB. The data is divided into 36 weeks group, 37 weeks group, and ≥38 weeks group. The maternal demographic and pregnancy characteristics were observed. The primary outcome was neonatal composite morbidity, which was defined as having one or more of the following: neonatal intensive care unit's admission, low Apgar score, the requirement of mechanical ventilator support, respiratory distress syndrome, and stillbirth or perinatal/ neonatal mortality. The optimal gestational age for delivery according to chorionicity is determine based on the neonatal composite morbidity. Results: A total of 949 sets of twins delivered at HSIJB over ten years, from which 360 women with uncomplicated twin pregnancies and 720 neonatal outcomes were eligible for the study (144 DCDA and 216 MCDA). In DCDA twins, the composite morbidity was least in the 37 weeks group, followed by the ≥ 38 weeks group and then 36 weeks group. On the contrary, more composite morbidity wasseen in the MCDA twinning group at 36 weeks group, followed by the 37 weeks group and later in ≥ 38 weeks group. However, the association between the gestational age at delivery with composite morbidity in MCDA twin were insignificant. Conclusion: Our data suggest that the optimal gestational age for delivery in uncomplicated DCDA twins was at 37 weeks and MCDA twins at ≥38 weeks. 2020 Thesis http://eprints.usm.my/57330/ http://eprints.usm.my/57330/1/DR%20NURLIZA%20BINTI%20MD%20NOR-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RG551-591 Pregnancy
spellingShingle	RG551-591 Pregnancy Nor, Nurliza Md A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
description	Introduction: The incidence of twin pregnancy is increasing worldwide1, and so does in Malaysia. It is associated with a higher risk of morbidity and mortality throughout pregnancy to both mother and fetus. This study aims to determine the maternal and fetal characteristic of twin pregnancies in Hospital Sultan Ismail Johor Bahru (HSIJB) and to observe the association between the gestational age at delivery and the delivery outcomes in uncomplicated twin pregnancies. Methodology: This is a retrospective observational study of women with uncomplicated monochorionic and dichorionic twin pregnancies delivered at 36 completed weeks or beyond from January 2009 until December 2018 in HSIJB. The data is divided into 36 weeks group, 37 weeks group, and ≥38 weeks group. The maternal demographic and pregnancy characteristics were observed. The primary outcome was neonatal composite morbidity, which was defined as having one or more of the following: neonatal intensive care unit's admission, low Apgar score, the requirement of mechanical ventilator support, respiratory distress syndrome, and stillbirth or perinatal/ neonatal mortality. The optimal gestational age for delivery according to chorionicity is determine based on the neonatal composite morbidity. Results: A total of 949 sets of twins delivered at HSIJB over ten years, from which 360 women with uncomplicated twin pregnancies and 720 neonatal outcomes were eligible for the study (144 DCDA and 216 MCDA). In DCDA twins, the composite morbidity was least in the 37 weeks group, followed by the ≥ 38 weeks group and then 36 weeks group. On the contrary, more composite morbidity wasseen in the MCDA twinning group at 36 weeks group, followed by the 37 weeks group and later in ≥ 38 weeks group. However, the association between the gestational age at delivery with composite morbidity in MCDA twin were insignificant. Conclusion: Our data suggest that the optimal gestational age for delivery in uncomplicated DCDA twins was at 37 weeks and MCDA twins at ≥38 weeks.
format	Thesis
qualification_level	Master's degree
author	Nor, Nurliza Md
author_facet	Nor, Nurliza Md
author_sort	Nor, Nurliza Md
title	A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
title_short	A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
title_full	A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
title_fullStr	A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
title_full_unstemmed	A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes
title_sort	retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in hospital sultan ismail johor bahru : the association between gestational age at delivery and the neonatal outcomes
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2020
url	http://eprints.usm.my/57330/1/DR%20NURLIZA%20BINTI%20MD%20NOR-24%20pages.pdf
_version_	1794024022119284736

A retrospective study (2009-2018) on the outcome of uncomplicated twin pregnancies in Hospital Sultan Ismail Johor Bahru : the association between gestational age at delivery and the neonatal outcomes

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