Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women

This study aimed to investigate the effects of lactobacilli probiotics in preventing the recurrences of vulvovaginal candidiasis (VVC) in 78 pregnant women with VVC (probiotic, n = 39; placebo, n = 39) and the potential benefits on quality of life. The lactobacilli probiotic (SynForU-HerCare; two...

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Main Author: Ang, Xin Yee
Format: Thesis
Language:English
Published: 2022
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Online Access:http://eprints.usm.my/59664/1/24%20Pages%20from%20ANG%20XIN%20YEE%20-%20TESIS.pdf
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spelling my-usm-ep.596642023-12-13T01:21:07Z Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women 2022-09 Ang, Xin Yee T1-995 Technology(General) This study aimed to investigate the effects of lactobacilli probiotics in preventing the recurrences of vulvovaginal candidiasis (VVC) in 78 pregnant women with VVC (probiotic, n = 39; placebo, n = 39) and the potential benefits on quality of life. The lactobacilli probiotic (SynForU-HerCare; two capsules/day of 9.5 log CFU/capsule) or placebo was administered for 8-weeks in a randomized, double-blind, and placebo-controlled study. Subjects were assessed for vaginal and gut health conditions at week-0, 4, and 8 via questionnaires and analyzed vaginal microbiota and inflammatory changes. The vulvovaginal symptom questionnaire covered vulvovaginal symptoms and quality of life. Probiotic group was exhibited the reduction of irritation (P=0.023) and discharge (P=0.011) starting week-4 and continued after week-8 (P<0.05) as compared to the placebo. Probiotic group was exhibited the reduction of concern about symptoms after week-4 (P=0.010) and continued after week-8 (P=0.001), accompanied by reduced impairment of daily activities (P=0.012) and continued after week-8 (P=0.026). Probiotic group was exhibited the reduction of recurrences of both emotional and social stress compared to the placebo at both week-4 and week-8 (P<0.05). Probiotic group showed higher defecation times per week at week-4 (P=0.010) and week-8 (P=0.001) compared to the placebo group. 2022-09 Thesis http://eprints.usm.my/59664/ http://eprints.usm.my/59664/1/24%20Pages%20from%20ANG%20XIN%20YEE%20-%20TESIS.pdf application/pdf en public masters Perpustakaan Hamzah Sendut Pusat Pengajian Teknologi Industri
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic T1-995 Technology(General)
spellingShingle T1-995 Technology(General)
Ang, Xin Yee
Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
description This study aimed to investigate the effects of lactobacilli probiotics in preventing the recurrences of vulvovaginal candidiasis (VVC) in 78 pregnant women with VVC (probiotic, n = 39; placebo, n = 39) and the potential benefits on quality of life. The lactobacilli probiotic (SynForU-HerCare; two capsules/day of 9.5 log CFU/capsule) or placebo was administered for 8-weeks in a randomized, double-blind, and placebo-controlled study. Subjects were assessed for vaginal and gut health conditions at week-0, 4, and 8 via questionnaires and analyzed vaginal microbiota and inflammatory changes. The vulvovaginal symptom questionnaire covered vulvovaginal symptoms and quality of life. Probiotic group was exhibited the reduction of irritation (P=0.023) and discharge (P=0.011) starting week-4 and continued after week-8 (P<0.05) as compared to the placebo. Probiotic group was exhibited the reduction of concern about symptoms after week-4 (P=0.010) and continued after week-8 (P=0.001), accompanied by reduced impairment of daily activities (P=0.012) and continued after week-8 (P=0.026). Probiotic group was exhibited the reduction of recurrences of both emotional and social stress compared to the placebo at both week-4 and week-8 (P<0.05). Probiotic group showed higher defecation times per week at week-4 (P=0.010) and week-8 (P=0.001) compared to the placebo group.
format Thesis
qualification_level Master's degree
author Ang, Xin Yee
author_facet Ang, Xin Yee
author_sort Ang, Xin Yee
title Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
title_short Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
title_full Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
title_fullStr Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
title_full_unstemmed Effects Of Lactobacillus Spp. Against Vaginal Candidiasis In Pregnant Women
title_sort effects of lactobacillus spp. against vaginal candidiasis in pregnant women
granting_institution Perpustakaan Hamzah Sendut
granting_department Pusat Pengajian Teknologi Industri
publishDate 2022
url http://eprints.usm.my/59664/1/24%20Pages%20from%20ANG%20XIN%20YEE%20-%20TESIS.pdf
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