Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor

Three-dimensional (3D) printing or additive manufacturing is a promising technology to revolutionise traditional manufacturing methods. Nowadays, numerous studies have utilised 3D printing technology to replace conventional electrodes in the fabrication of electrochemical sensors and biosensors due...

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Main Author: Omar, Muhamad Huzaifah
Format: Thesis
Language:English
Published: 2023
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Online Access:http://eprints.usm.my/60333/1/MUHAMAD%20HUZAIFAH%20BIN%20OMAR%20-%20TESIS%20cut.pdf
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spelling my-usm-ep.603332024-04-02T04:38:47Z Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor 2023-08 Omar, Muhamad Huzaifah QD1-65 General Including alchemy Three-dimensional (3D) printing or additive manufacturing is a promising technology to revolutionise traditional manufacturing methods. Nowadays, numerous studies have utilised 3D printing technology to replace conventional electrodes in the fabrication of electrochemical sensors and biosensors due to its low cost, rapid prototyping, and flexibility in design. The main aim of this study is to explore the 3D-printed electrode’s potential as an electrochemical biosensor for breast cancer gene (BRCA1) detection. The first section focuses on the electrochemical performances of 3D-printed polylactic acid/carbon fiber (PLA/CF) electrodes. A novel electrochemical treatment using the differential pulse voltammetry (DPV) technique in hexaammineruthenium (III) chloride (RuHex) solution is proposed. Electrochemical characterisations revealed that the DPV-RuHex electrochemical treatment significantly improved the electrochemical performance of the 3D PLA/CF electrode. Furthermore, field emission scanning electron microscopy (FESEM) micrographs demonstrated that more PLA layers degraded after the treatment, which increased the electrode’s electroactive surface area. The second part investigates the effect of DPV treatment in RuHex and sodium hydroxide (NaOH) solutions on the 3D-printed PLA/graphene (PLA/G) electrode. The electrochemical analyses revealed no significant difference between the two treatments. 2023-08 Thesis http://eprints.usm.my/60333/ http://eprints.usm.my/60333/1/MUHAMAD%20HUZAIFAH%20BIN%20OMAR%20-%20TESIS%20cut.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Kimia
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic QD1-65 General Including alchemy
spellingShingle QD1-65 General Including alchemy
Omar, Muhamad Huzaifah
Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
description Three-dimensional (3D) printing or additive manufacturing is a promising technology to revolutionise traditional manufacturing methods. Nowadays, numerous studies have utilised 3D printing technology to replace conventional electrodes in the fabrication of electrochemical sensors and biosensors due to its low cost, rapid prototyping, and flexibility in design. The main aim of this study is to explore the 3D-printed electrode’s potential as an electrochemical biosensor for breast cancer gene (BRCA1) detection. The first section focuses on the electrochemical performances of 3D-printed polylactic acid/carbon fiber (PLA/CF) electrodes. A novel electrochemical treatment using the differential pulse voltammetry (DPV) technique in hexaammineruthenium (III) chloride (RuHex) solution is proposed. Electrochemical characterisations revealed that the DPV-RuHex electrochemical treatment significantly improved the electrochemical performance of the 3D PLA/CF electrode. Furthermore, field emission scanning electron microscopy (FESEM) micrographs demonstrated that more PLA layers degraded after the treatment, which increased the electrode’s electroactive surface area. The second part investigates the effect of DPV treatment in RuHex and sodium hydroxide (NaOH) solutions on the 3D-printed PLA/graphene (PLA/G) electrode. The electrochemical analyses revealed no significant difference between the two treatments.
format Thesis
qualification_level Master's degree
author Omar, Muhamad Huzaifah
author_facet Omar, Muhamad Huzaifah
author_sort Omar, Muhamad Huzaifah
title Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
title_short Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
title_full Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
title_fullStr Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
title_full_unstemmed Fabrication Of Three Dimensional (3d)-Printed Electrodes-Based Thermoplastic Carbon Nanomaterials For Electrochemical Breast Cancer Dna Biosensor
title_sort fabrication of three dimensional (3d)-printed electrodes-based thermoplastic carbon nanomaterials for electrochemical breast cancer dna biosensor
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Kimia
publishDate 2023
url http://eprints.usm.my/60333/1/MUHAMAD%20HUZAIFAH%20BIN%20OMAR%20-%20TESIS%20cut.pdf
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