Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.

In 2010, there were 19,337 cases of tuberculosis notified with incidence rate of 66.9 per 100,000 population of which 443 (2.3%) were children. Among factors identified that contributed toward treatment outcome of tuberculosis in children were difficulty in diagnosis and ensuring compliance. This st...

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Main Author:	Adam, Farzaana
Format:	Thesis
Language:	English
Published:	2012
Subjects:	R Medicine (General) RC306-320.5 Tuberculosis
Online Access:	http://eprints.usm.my/60981/1/DR%20FARZAANA%20ADAM%20-%20e.pdf
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id	my-usm-ep.60981
record_format	uketd_dc
spelling	my-usm-ep.609812024-11-20T03:28:41Z Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia. 2012 Adam, Farzaana R Medicine (General) RC306-320.5 Tuberculosis In 2010, there were 19,337 cases of tuberculosis notified with incidence rate of 66.9 per 100,000 population of which 443 (2.3%) were children. Among factors identified that contributed toward treatment outcome of tuberculosis in children were difficulty in diagnosis and ensuring compliance. This study was conducted to determine the treatment outcome of tuberculosis in children for East Coast of Malaysia and identify factors associated with the treatment outcome. A cross sectional study was conducted through review of medical reports from 2009 through 2011 of children less than 15 years old at eight selected hospitals situated in the states of Kelantan, Terengganu and Pahang. Children who did not complete the treatment by the end of the study period were excluded. Successful treatment outcome was defined as cured and completed treatment. Unsuccessful treatment outcome was defined as cases that defaulted, failed treatment or died. There were 93 children diagnosed and treated as tuberculosis of which 53 (57.0%) were from 5 to 14 years of age, 51 (54.8%) were female, 74 (79.6%) were Malay and 30 (32.3%) came from families with monthly household income of less than R.M800. There were 64 (68.8%) with pulmonary tuberculosis, 23 (24.7%) with weight for age less than the 3rd centile, 25 (26.9%) with comorbidities, 49 (52.7%) with contact to tuberculous patient. There were 67 (72.0%) children which completed treatment, 9 (9.7%) cured, 11(11.8%) defaulted, 1 (1.1%) failed treatment and 5 (5.4%) died. These led to 76 (81.7%) with successful treatment outcome and 17 (18.3%) with unsuccessful treatment outcome. Through multiple logistic regression analysis, non Malay race (odds ratio: 5.84; 95% confidence interval: 1.59, 21.49; p = 0.008) and monthly household income of less than RM800 (odds ratio:6.98; 95% confidence interval: 1.85, 26.28; p = 0.004) were factors found to have significant association with unsuccessful treatment outcome. The main factors associated with unsuccessful treatment outcome identified were low household income and Orang Asli as they comprised of 14 (73.7%) of the non-Malay race. 2012 Thesis http://eprints.usm.my/60981/ http://eprints.usm.my/60981/1/DR%20FARZAANA%20ADAM%20-%20e.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General) RC306-320.5 Tuberculosis
spellingShingle	R Medicine (General) RC306-320.5 Tuberculosis Adam, Farzaana Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
description	In 2010, there were 19,337 cases of tuberculosis notified with incidence rate of 66.9 per 100,000 population of which 443 (2.3%) were children. Among factors identified that contributed toward treatment outcome of tuberculosis in children were difficulty in diagnosis and ensuring compliance. This study was conducted to determine the treatment outcome of tuberculosis in children for East Coast of Malaysia and identify factors associated with the treatment outcome. A cross sectional study was conducted through review of medical reports from 2009 through 2011 of children less than 15 years old at eight selected hospitals situated in the states of Kelantan, Terengganu and Pahang. Children who did not complete the treatment by the end of the study period were excluded. Successful treatment outcome was defined as cured and completed treatment. Unsuccessful treatment outcome was defined as cases that defaulted, failed treatment or died. There were 93 children diagnosed and treated as tuberculosis of which 53 (57.0%) were from 5 to 14 years of age, 51 (54.8%) were female, 74 (79.6%) were Malay and 30 (32.3%) came from families with monthly household income of less than R.M800. There were 64 (68.8%) with pulmonary tuberculosis, 23 (24.7%) with weight for age less than the 3rd centile, 25 (26.9%) with comorbidities, 49 (52.7%) with contact to tuberculous patient. There were 67 (72.0%) children which completed treatment, 9 (9.7%) cured, 11(11.8%) defaulted, 1 (1.1%) failed treatment and 5 (5.4%) died. These led to 76 (81.7%) with successful treatment outcome and 17 (18.3%) with unsuccessful treatment outcome. Through multiple logistic regression analysis, non Malay race (odds ratio: 5.84; 95% confidence interval: 1.59, 21.49; p = 0.008) and monthly household income of less than RM800 (odds ratio:6.98; 95% confidence interval: 1.85, 26.28; p = 0.004) were factors found to have significant association with unsuccessful treatment outcome. The main factors associated with unsuccessful treatment outcome identified were low household income and Orang Asli as they comprised of 14 (73.7%) of the non-Malay race.
format	Thesis
qualification_level	Master's degree
author	Adam, Farzaana
author_facet	Adam, Farzaana
author_sort	Adam, Farzaana
title	Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
title_short	Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
title_full	Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
title_fullStr	Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
title_full_unstemmed	Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
title_sort	treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2012
url	http://eprints.usm.my/60981/1/DR%20FARZAANA%20ADAM%20-%20e.pdf
_version_	1818647364637818880

Treatment outcome of tuberculosis in children and its associated factors in east coast of malaysia.

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